ID A0A226DHA4_FOLCA Unreviewed; 505 AA.
AC A0A226DHA4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Thyroid hormone receptor beta {ECO:0000313|EMBL:OXA44613.1};
GN ORFNames=Fcan01_20461 {ECO:0000313|EMBL:OXA44613.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA44613.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA44613.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA44613.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA44613.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA44613.1}.
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DR EMBL; LNIX01000019; OXA44613.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226DHA4; -.
DR STRING; 158441.A0A226DHA4; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR24082; NUCLEAR HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24082:SF482; RETINOID X RECEPTOR; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:OXA44613.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 29..112
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 138..379
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
SQ SEQUENCE 505 AA; 57654 MW; 93DCB6F3BFB9EDE2 CRC64;
MEKGLQRNNI EKHQGYYTGK KSKRNSIRDM LCNVCGDKAR SHNYGGITCN SCRSFFQHFV
LKNFIIFKNM DSINDCKFQG NCAINQVTRR NCTICRFYKC VKIGMEPAWV VSDYQRTEKL
KQGKLSSIPS PDYKLNDEDS AKIADMLKYY NTACELIPYN FPIRAKDEKL TVKKLQILLI
GGMSVSIRRF VCFANMIPEF KRLSLHDQTN LLRRSVTEMD ILRNAVLFDV EKRTWSHVIG
SEKHPIVHFD EFLGIWPEDV LEIGYNIYKR LKSHAPDESS IMLLIVVVLF SDYGGGEACS
EFEDSPAINA AQEHYAALLE KYLKFVHGET KGRLAFPRLL CHLMEITQAS LFHQGAPLNL
SDHQVDKMHQ HLLELQRVVN PSSLENNKTF QGREDFRGEK ECCRKRLRSA KPPVSSDNEQ
TEVNQGQNFP SLIHNFACPP GEWGIKPYFF EKGPHVGVKK AFMRRMPKLV TNPLDSLVAD
VSGLSISCND AKEEEFIGTN GTNGS
//
