ID A0A226DJG7_FOLCA Unreviewed; 478 AA.
AC A0A226DJG7;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN ORFNames=Fcan01_19568 {ECO:0000313|EMBL:OXA45665.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA45665.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA45665.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA45665.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA45665.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA45665.1}.
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DR EMBL; LNIX01000017; OXA45665.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226DJG7; -.
DR STRING; 158441.A0A226DJG7; -.
DR OMA; SCDILCC; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008253; F:5'-nucleotidase activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19334; Wnt_Wnt2_like; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006434; Pyrimidine_nucleotidase_eu.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF05822; UMPH-1; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..478
FT /note="Protein Wnt"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011991081"
SQ SEQUENCE 478 AA; 53880 MW; 69E429E167EB34C8 CRC64;
MSALRLLLIF SLTGPFLPGV EGSAWWVSFF AGSGNFLGFS FPVFRKKTKK SNPRLSEKFG
VQCVTGYLSR YFTQFDTLAV NEHHKNFCKV VPHLNKRQRE ICNKNSDLVR VIGDGVKDGV
SECQYQFRYQ KWNCSTFRND PTLFGKSLVR GGSRESALLQ AMHSSSAIYK LAKACSKGHP
GCGCSTEISN GQIRNASRYD ARFKWDGCDQ VVKFSTNFVR RFIDAAELRV SDAKAKFNLH
NNRVGRIIVR KKLKKVCKCH GLSGSCSMRT CWSTLPSFRE IGDALRGKYD AGVEVIFTPS
GSNVIPVRAG HRKLTKVNLI FYDMSPDYCR PNFGQGSVGT KGRPCLDASD GEESCDILCC
RQKYEIVKVR YSQRCNCTFT WCCQVSCQTC NGTRFQFNKN ENALRHSTYF AELQSRRNAL
LLGDSLGDVH MDHGMPSSHK EEGVVLKIGF LNDKVLEDDQ SFKLMQLILS RIIKDAKQ
//
