ID A0A226DMC1_FOLCA Unreviewed; 1387 AA.
AC A0A226DMC1;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Leucine-rich repeat-containing protein 24 {ECO:0000313|EMBL:OXA46329.1};
GN ORFNames=Fcan01_18570 {ECO:0000313|EMBL:OXA46329.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA46329.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA46329.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA46329.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA46329.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA46329.1}.
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DR EMBL; LNIX01000015; OXA46329.1; -; Genomic_DNA.
DR STRING; 158441.A0A226DMC1; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45842:SF12; KEKKON 5, ISOFORM A; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00369; LRR_TYP; 5.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 346..463
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 547..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 652..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 719..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 813..836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 914..1016
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1030..1081
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1178..1279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1299..1387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..633
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..703
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..1006
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1034..1055
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1225..1249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1305..1319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1354..1373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1387 AA; 149927 MW; 7DE95A65382774A6 CRC64;
MRNNEHQLGG RDGESGDATK LKKKASSHKR IWHPHSESCC AGAIMKSPPL SGPPPSPVKF
PLGRGGGGGM LPRSLTSWRT LWPGLVVVAF LLVFCLGSVG GTEDWTLQCP TGCKCTWVSG
KKTADCRGSH WTSIPSGLSA EVQVLEMGGI TIKYLPKDAF KQVGLVNLQK VFLQNCRIER
IDRDAFRDLT IMIELDLSGN LVSGIEMETF ESNVRLRELK LSKNPLTKLT GSSFPPLMYL
KLLDLSDCQL STLPKKAFEK LSVLESLSLS GNRFTYLSRE LLKPLTKLKS LQLAGNPWKC
DCRLKTLRDW VIQKNLFQHH TRCAEPAIVS NFAWDQLVSL DFSCRPEIVS VQINGKPTDA
LLVHTDIGSD ITLQCLVRGN PPPDLKWVRD GQVLTNNSRS YGKSYYLHIG GEEGWELEDP
YSNTDDYRGR WVNLTIQKTD PEDAGEYTCV GSNSGGVVEK NLTLNFQDVP SGAGVGHGLG
GLAAGAYRDT GWIWILITTL AVLVFATTLI TLVCFCSRRR RVKTTRAQDL KNDGKLNGGG
SGYIECPNLS SSTSSKSSKL DPQLTKIRDS PTSSAPTPRF SSGGDPPPSS LQHLRNSASS
SPSSHQQQHH QQSQTHPPCP TSSLAQTGRH GKSVTVPCSA DVELTYRINP MHCTNNSPAN
SGGGGGMGGT YTRRPTRCTF QREDSSNSTS NGPSSSSTFC DSSGQYQPIF HHEMIELHPP
SNSSPGSRIG VLDPVTPSSQ NSGTTYFHHH HHHPSPYNNP SAEMILVSQQ ADEKEIVLPP
PLQFGPSRNT ACCTNMQQQY EHCCGGYVQQ NHGHHHHPHV HPHNNNSPYP QNNEKSTRFE
NDNLVVMSRT TECQIPSPPS SLVPVHSFCP SNYASISRSM RLPEKVPPPP PQRDLTTYAT
LSCNYNPLVD KAAHLSSAQQ QQSPSGSSSS YNTRAFEQQQ QKHNNCSERE NNSMKCGDQE
ESRSSQQPIL TQNQITKETQ TGGGGGGEDQ PNQRQLLLTP SSRSPGSGKV GDEDGTTMLL
MKEKYLVGPD ARSQSVDIIT SSPYPGENGS VYRPSSAQMM APPPPSHALT GGPHGGGPSS
EYPDLLDLPH TRFQESPAPS TTSTLPDSTR MLITPQGLNP SIVVNPSRLG YNHPQAIYSN
GGGGRPSFGL PFSPAEQPAF VPAGMRPGYV TLPRRHRVPS WSPGPSSNFD PASSPMGPPS
PTGSAATISL PFVKARPKYD NLGPRTTADG SSRLSLDNLP GNGGTSTPNF HPHPGLIGGT
LGRHNVLRST PTPSMLGQPI SHFAPIQEVE HISSPVEVDN DEEAPISTPS DKHKPSTKTD
RTPTPSGSRG SSPTKGKKVP PKPPPKPVKK NVNANPAEIS NGVVTTTPPE KINDPSTAIA
GDDGTEV
//
