ID   A0A226DMJ5_FOLCA        Unreviewed;      1248 AA.
AC   A0A226DMJ5;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   22-FEB-2023, entry version 22.
DE   SubName: Full=Dedicator of cytokinesis protein 9 {ECO:0000313|EMBL:OXA46765.1};
GN   ORFNames=Fcan01_18464 {ECO:0000313|EMBL:OXA46765.1};
OS   Folsomia candida (Springtail).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC   Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX   NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA46765.1, ECO:0000313|Proteomes:UP000198287};
RN   [1] {ECO:0000313|EMBL:OXA46765.1, ECO:0000313|Proteomes:UP000198287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VU population {ECO:0000313|EMBL:OXA46765.1,
RC   ECO:0000313|Proteomes:UP000198287};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OXA46765.1};
RA   Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT   "The genome of Folsomia candida.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00984}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXA46765.1}.
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DR   EMBL; LNIX01000014; OXA46765.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A226DMJ5; -.
DR   STRING; 158441.A0A226DMJ5; -.
DR   Proteomes; UP000198287; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 1.20.58.740; -; 1.
DR   Gene3D; 1.25.40.410; -; 1.
DR   InterPro; IPR026791; DOCK.
DR   InterPro; IPR043161; DOCK_C_lobe_A.
DR   InterPro; IPR043162; DOCK_C_lobe_C.
DR   InterPro; IPR027357; DOCKER_dom.
DR   InterPro; IPR046769; DOCKER_Lobe_A.
DR   InterPro; IPR046770; DOCKER_Lobe_B.
DR   InterPro; IPR046773; DOCKER_Lobe_C.
DR   PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR   PANTHER; PTHR23317:SF76; LD20667P; 1.
DR   Pfam; PF06920; DHR-2_Lobe_A; 1.
DR   Pfam; PF20422; DHR-2_Lobe_B; 1.
DR   Pfam; PF20421; DHR-2_Lobe_C; 1.
DR   PROSITE; PS51651; DOCKER; 1.
PE   3: Inferred from homology;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198287}.
FT   DOMAIN          819..1233
FT                   /note="DOCKER"
FT                   /evidence="ECO:0000259|PROSITE:PS51651"
FT   REGION          391..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          524..573
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..573
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1248 AA;  139495 MW;  DF0720B396C0F3D4 CRC64;
     MKGMRFLKIA ESVVHKSAFG YFLNDTLIDA WIDLFETGDG ATIASSLEHS RNLFSMIVKS
     IAVQGIKSPA NPEESKLVKL VQLFTSEIVH RCQSGDQTLS RGANENEIAF ISALLSVVSQ
     RHVVFAAINA YLACFGPGDS HKVQDFKFNM LQSLVEHPLF LELNSAEGDE EYTRLEHCLW
     CKRHFLAATV MKQCRSGLGE VTNVRCQALK VIMIGLARHE SCDSTHPMWI PWLRVVCDNL
     HRITKVVNHS SRCSSVSTVL SATTSTLVHQ ALIKSISGQN HEGHNHGASC SQHSREGSQI
     SNTINLSTIT PRHPLLGTES SRSSSLSLNV PNGVSPSISQ NSSMVNINAI GNGESISAGD
     RLSVDRMSFG SVNNCDYLDA ISAIKTSNPA ASTIVPSTTG GSDTDTIVNE GGSNGSGETQ
     SEGDPDSQSM KRVANATIGD ADKSNIVQRR YDRLADDETR PLLVGGLYIL KKMGNDRLRI
     FWNRSSTQER ASLLQMVLLA CVQFTNARKN STITKTKIVG ISVPPPTMPP SPRSAVPNKK
     WSSLPSKTTE ESAVDGNPVE MTSPSRKTSN TSPFDSFNEW KTLNTETTFV CIDTLSNLCS
     ACKGEDNEMR EVIRTSLNVA KAAEDTRAML STLQNLAQVE ELAAIVFAKG NEDLTHQLFC
     ELLTGFGTSY LIHICVLILG KLFMNDPNRT TSQSLFAISS LSLDQVFVHN FRKALNLLER
     NMSVNDRSSF MLSITEKLSF IDVSEADGTT YSKANTLVLS GSQPVSNGII KNKLMRTVST
     TALDLSNRLS TVMNSLWVLK ACTNEYRIPE VYLKLANSYA YYAKGRLRIE TFDSLKSEHL
     NKKKYSEALM CELHVAARLA RQTTTSAEIK RVMLGISRNL RDEFEEEADD NQEEADYTEE
     LIDRMEQCVH LCEKSERYEV MLEVYRMLVD IQESTSDHAA LEHYYTQMAR ACGLIQKKRE
     RFHGTYYRVA FYRPKKQCTS RPMEVFIYKE PNVTSLMEIC GKVETAENVI IISGEVDQLP
     DDDHIYATIT HVSPLPSSSP RRKLWSEDFR RHQNISKFTY DTPFAVKSHD KISIDNKAAV
     HQQWKRRTTV TTEYTFPAVV SRLRVVESTE EDLSPIIVAI DDMQRRVLEL RSEFNSGCIK
     RIQLRLQGSI SVQVNQGPLA YVRAFLEKEN EYPASDIHKL KAIYRDFVEC CRELLIKNAA
     MILPEQVDYQ TQLETDYVRL CQVLNPYIGL GHLELGVNRM SRASVSSY
//