ID A0A226DUH1_FOLCA Unreviewed; 266 AA.
AC A0A226DUH1;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Eukaryotic translation initiation factor 2-alpha kinase 1 {ECO:0000313|EMBL:OXA48883.1};
GN ORFNames=Fcan01_16469 {ECO:0000313|EMBL:OXA48883.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA48883.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA48883.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA48883.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA48883.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA48883.1}.
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DR EMBL; LNIX01000011; OXA48883.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226DUH1; -.
DR STRING; 158441.A0A226DUH1; -.
DR OrthoDB; 8734at2759; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0017148; P:negative regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01670; Death; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR11042; EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED; 1.
DR Pfam; PF00531; Death; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Initiation factor {ECO:0000313|EMBL:OXA48883.1};
KW Kinase {ECO:0000313|EMBL:OXA48883.1};
KW Protein biosynthesis {ECO:0000313|EMBL:OXA48883.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW Transferase {ECO:0000313|EMBL:OXA48883.1}.
FT DOMAIN 22..96
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT DOMAIN 129..266
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 266 AA; 30289 MW; 0C4157FAAE6D91BC CRC64;
MAEPVNLEHI KVLLQDTTFL NEWKQVSDAL GIPARDLFSM NSKLNSGNAT MYDVIQWMLE
TWRGRNGNDV ATVAKLISVL ESEDLRNAAD LLKDFSKRSA ASTPQTRPIP IEMSTQDNAA
SEGMQQRNLV VLERLDQGTL SEVFKVRSIF DNKEYAIKRI SVGQFLLLTK TSGAADAFEF
FSKFMREVLV MAKLPEHPNI VAYREAWFEG TLQQTLTEWL RRPESMPPPT PVLKDAPKRQ
IVVTEAEKNT FMCIKMELMD TNLSQW
//
