ID A0A226DW08_FOLCA Unreviewed; 1726 AA.
AC A0A226DW08;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Phthiocerol synthesis polyketide synthase type I PpsD {ECO:0000313|EMBL:OXA49665.1};
GN ORFNames=Fcan01_15638 {ECO:0000313|EMBL:OXA49665.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA49665.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA49665.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA49665.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA49665.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA49665.1}.
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DR EMBL; LNIX01000010; OXA49665.1; -; Genomic_DNA.
DR STRING; 158441.A0A226DW08; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198287}.
FT DOMAIN 13..431
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 1726 AA; 191227 MW; 087B264776ADFC13 CRC64;
MSPDIEVPGK TLNEPIAIVG VAFRLPGASD GVTLWKNLMS ATDSVDFVPR DRWTSEKGCH
GLTKEHRSFR AGFIDGDVDK FDATFWGLSP LELGFIDPQA RLLLQLSWEA LESAGITPGS
LRGTSAAVLM GIWRDEYKDL VVSSSSVIGG EELRRYMGCS IGSSASRIAQ CFGMTGPTEG
IELGCASSSY AIGAAMRHLR NRRTNLALAG GANLILKPCK TDDFQGVVSP TSRSKVFQED
ADGFARAEGG IVYVLKRVTD AIKDGDNILG LIRGFGSSQD GLTRNFGTPT IGGEREAMLV
ALEDAEVNPE DIGWVEMHGT GTRVGDPTEV AATRIAYQIS SGERGHPLTV TSIKANIGHT
EGVSGAASLL KVLLAMKHGF IPPQLLTADL NHGIDFNGLV IPRTAVHWDG PLAGISSFGI
TGTNTHMISV GALAELGRKH VEALKLLELE DGDDQLAAYC YTASTCRHHF DEYRSIATGR
NLFELLKSLR SNNYELNNMT NFQHNTIRIK PTRPTSISFL FPGQGCQYIG MGLELYNSCA
TYRRHFDEVN SHFIDIGGID LLEWIRDGKD IPFYPQLSIF AVEYALLNMW KEWGVTPNLC
VVGHSSGEVM AAMAVGVLNL ATAVRLLVFT RQTLINEVEP GQMVALMTDE AMTLQMINQY
AERCFMENKS ESSWIDISAL NSYNQTVVSG PVETSKKFST FVITYYSTKT SLLKFVDNAF
HSRSFGKASN TFETNLEKLD FPERNRGVKY ISSMYRRELD DSENLDISYW SKLFTKPVKF
VGSAAAATTS VGAKLFLEIS PHPTLAPLMK DNCPQNDLIC IPSLMKDAEN WITLLNAIST
LYLHRVELDW SRIWISLFGE DILRNKVSHL LPTYPFQNEG PFWFSPLTTL SQDSEVVHRN
KIIHPLLGSM PAVPKFDEIN RITIFETSPG YVEMGFAVAT LLGKTEKFNN IKLSKVEIKT
VLSLDVKSDI QTNVVYDGEG FNISISSRGD HTEGMWTLHA SLNAKVITPD VYTIKPEKHL
GNFTGESLPS PYPESLRAGV VTPIFDTDGF GSFMVHPIIL DALLQITLLA QQDSLTTLRV
PVAISEFELV CSASGNIGKN TCARQIRAQA GINSSTLFIQ GADLKWRTLA SMTNLRTIST
TTKAVRRTIE GSNEMSDRKD HDQLLPLFVE EWVKDDQLVN YSQSICEQFS SCKTISRPAA
EIQDYKLISS YIGKCVAETL NLLGFSDFTH NQLITRCDIA LHLGLSHLAP NFLARLLKYA
GQAGLLKEYS LTEYIVLPYS DCLTHNLLAT NYDKHLPEDW AFVEFYTSKL TSFLSGTESI
LPYLFPPSLP SLEPPNQIVS NETSVNTNFS AERFYSATIA SYLTEDFIVV FTSFLKDNGQ
RLRILEVGAG TGSATRELLH HLRDSSSTYT FTDISINFLN RAEASLPHVP GDLEKDALVQ
VFENETFNVI IANNVLHATT DINRVVENLR LLLSPKGNIF IAEQLHPSAF VHIIFGHCKG
YWLFNDGIRS DHCLIDGDAW KLVLQSVGYG EVSIVENKDF HFGIIIATNK EDVSPPPSFI
VIASSDQDQF ANQLVASNKE YATLYNISEA NIVIHPENKI VYCFPQVLKD NIPALNQVRK
QLEHFLRFSR ALVSVGRVEL ILVSHGLIPV GDTEARYPVA GAIRGFSRTL ANEMLELDIT
WVDLDDDEST MQQIQEVVAE IRNKGTLRNR DSDPFVTVSF EYNCLH
//
