ID   A0A226E0W4_FOLCA        Unreviewed;       461 AA.
AC   A0A226E0W4;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Signal transducer and transcription activator {ECO:0000313|EMBL:OXA50607.1};
GN   ORFNames=Fcan01_14349 {ECO:0000313|EMBL:OXA50607.1};
OS   Folsomia candida (Springtail).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC   Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX   NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA50607.1, ECO:0000313|Proteomes:UP000198287};
RN   [1] {ECO:0000313|EMBL:OXA50607.1, ECO:0000313|Proteomes:UP000198287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VU population {ECO:0000313|EMBL:OXA50607.1,
RC   ECO:0000313|Proteomes:UP000198287};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OXA50607.1};
RA   Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT   "The genome of Folsomia candida.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transcription factor STAT family.
CC       {ECO:0000256|ARBA:ARBA00005586}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXA50607.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LNIX01000008; OXA50607.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A226E0W4; -.
DR   STRING; 158441.A0A226E0W4; -.
DR   Proteomes; UP000198287; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.238.10; EF-hand; 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR001217; STAT.
DR   InterPro; IPR048988; STAT_linker.
DR   PANTHER; PTHR11801; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; 1.
DR   PANTHER; PTHR11801:SF43; SIGNAL TRANSDUCER AND TRANSCRIPTION ACTIVATOR; 1.
DR   Pfam; PF21354; STAT_linker; 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW   SH2 domain {ECO:0000256|ARBA:ARBA00022999}.
FT   DOMAIN          242..304
FT                   /note="Signal transducer and activator of transcription
FT                   linker"
FT                   /evidence="ECO:0000259|Pfam:PF21354"
SQ   SEQUENCE   461 AA;  52699 MW;  FB21560FF970C3B2 CRC64;
     MDNGDFRHEF NQLEHEIDGL DFQMKNWNTN QRRLNWTGRI TDANDLTGFE AFAVVARNIE
     TRLRHTVQIL KNMMQLHTQD EEGITPFQRA IHATQKLIHT SLIFTNQPNK YLSSAGTAEK
     TIRIKSLLFH YRFGSVSPNG SGTQVVRCCI IDEPIAEMVA TSSTGDITEE QVAFKFNNVV
     SETQDFNNNQ YEIVFREFAE MTRFHAAGFH RLSNPFILTT NVSLYHDAWS TLLWDVNFAP
     LHRTPFAVPA EVSWLHFIEA IDNDFSNAGR RLSDQNKEYL KTKLATRSTD GQDVVTRDRF
     CNETPLKFVI SGERKDVTLA NWLFNILKLL MNPPPVILRE WIENKVTGFI STSELEAALT
     ASAVGTFMIR FSENVKGAVT MQFKVQRQDN SVGLAKFGPF TEAMLRSHNS SLGYIIRTCP
     QLRILYPDIR VEEAFPIGQD QLGEDDKILV ALGYKRNQFN L
//