ID A0A226EH00_FOLCA Unreviewed; 1467 AA.
AC A0A226EH00;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 {ECO:0000313|EMBL:OXA56021.1};
GN ORFNames=Fcan01_09607 {ECO:0000313|EMBL:OXA56021.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA56021.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA56021.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA56021.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA56021.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA56021.1}.
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DR EMBL; LNIX01000004; OXA56021.1; -; Genomic_DNA.
DR STRING; 158441.A0A226EH00; -.
DR OMA; KCENTND; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198287}.
FT DOMAIN 697..885
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 278..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1300..1336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1301..1336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1467 AA; 162847 MW; D1E577530ECD429E CRC64;
MTSLHNVESA PACLSQVSTT TAVSSSGISN NNSHDRSASG AVIVSPFWGR CTMSNRQVYI
LKGEISLLTA SLRRTPQQRW SSQQDLKGDF PLVKQLQALK ESLNINTKAA LSKISQDANY
FLVPFLDIIR SEDTSGPVTA LALSAIEKFI LNDLVNEGNG GTSAAEAITD AVIHAHFVST
DSSSDEIVLM KILQVLHRLF VCPLGALLSN ESVCELMQSC FRMCFIERAN ELLRKSAETA
LNDMVRLLFM RVKEFPVSTG KKTKILDPTL ELAVEVAREE TNKTEDSNID PVVATPSTES
EPSETPNIVH TQVPADGGEN NIEQVETITP SEGNNASLQN SSSDIHTPEP PVPSTTTSQI
PVINIVHPTP TQDSNNRNMN PNVVEFKNKR GIRFTTASDK SLEKIEEVEA DNSQQHHGAD
TGEEPLLKQM NTPYGIPCVR ELVRFLVSLI NPHEKQNSET MIHLGLKLLL IAVESDMEAI
AMHPPLQAIF KNELVKNLIA LLSYNSPNNN GSIILLTVLR ILFIIFDSMR MDMKYQLEVF
ITRLMEIIGD GQQNPININQ NQQSRWMYEQ RELALDYLTQ LWKLPTFVTE LYLNYDCDLF
CSNLFEDLTK LLSKNAFPMQ TGINSIHLLC LEGLASILDG IESHCTTRLN STSSGVNTSS
SSSSDESNSS VFYHDYEPGE VKLEKSDESG QLPTHEQLMA IRHKKKLYHT GSDQFNQNAS
KGIAFLQTNG ILSTPLDPAE VAQFLRDNPL LDKKTIGDYI SALKRGDILR EFVKAFDFKG
TRIDEALRLF LETFRLPGES PLISNILENF AEVWTCANDN PFVNVDAAYT LSYAVIMLNV
DQHNTNVKAQ CMTWEQFKKN LKGVNGGQEF DPEMLNQIYN AIKSDEIVMP AEHTGVLKEN
YLWKMLLRRG STSRSKFLCP KTDEGLYDHD LFSLSWGPIV AALSFIFDKT TDAAIVNKTI
TGFRKCATIS AHYGMSDVFD NLVISLCKFT TLISGNPDLG SNIKAQNASH TVFQLVHRHG
GILREGWKNF IDCLVSLFKM QTLPKMLTDA EDFTEPSGRV SLVRNTQTVT PRPETGLFSS
LYSYIALSTS DNSPGSKSNL DEEEVKKKTV TLIRECHPEL LLSESKFLPL DSLNELIKNL
IYASPVPENN LSRRKDYDED SVVFVLEVLI KICIQNRDRV MVFWDPLREH LFSMIVASAT
CDMQYLLERS TVGLLRLALR LMRKEDICGI VLQSLKILLY LRPSSIIHLS QQISFGLHEI
LKTTAANIHT TEDWTIIFAL LEYVGAGKVP SGPLTAVSVD VAPPSQPQLQ PSGSDSAINN
STLKSLGGSG LQHSQSQDPI AIPLSTEYSS GSDRGYTSDS ELEIRSTASN EHRLSGVSPA
QSWILLTHSQ TPEDTPLVTP PSSSPSKVAK TLVQERQQIN FTPDPKALMK SCETLSFLVR
DAAHITPDNF TICVAAIKSF VDACLGR
//
