ID   A0A226EHE8_FOLCA        Unreviewed;       518 AA.
AC   A0A226EHE8;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=E3 ubiquitin-protein ligase SINAT4 {ECO:0000313|EMBL:OXA57012.1};
GN   ORFNames=Fcan01_07687 {ECO:0000313|EMBL:OXA57012.1};
OS   Folsomia candida (Springtail).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC   Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX   NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA57012.1, ECO:0000313|Proteomes:UP000198287};
RN   [1] {ECO:0000313|EMBL:OXA57012.1, ECO:0000313|Proteomes:UP000198287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VU population {ECO:0000313|EMBL:OXA57012.1,
RC   ECO:0000313|Proteomes:UP000198287};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OXA57012.1};
RA   Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT   "The genome of Folsomia candida.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXA57012.1}.
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DR   EMBL; LNIX01000003; OXA57012.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A226EHE8; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000198287; Unassembled WGS sequence.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR004162; SINA-like_animal.
DR   InterPro; IPR008974; TRAF-like.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR013010; Znf_SIAH.
DR   PANTHER; PTHR45877; E3 UBIQUITIN-PROTEIN LIGASE SIAH2; 1.
DR   PANTHER; PTHR45877:SF2; E3 UBIQUITIN-PROTEIN LIGASE SINA-RELATED; 1.
DR   Pfam; PF21361; Sina_ZnF; 1.
DR   SUPFAM; SSF49599; TRAF domain-like; 1.
DR   PROSITE; PS51081; ZF_SIAH; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00455};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00455};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00455}.
FT   DOMAIN          94..152
FT                   /note="SIAH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51081"
FT   REGION          484..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   518 AA;  58080 MW;  21BC5C4461381DC3 CRC64;
     MQSEDIGYGP NCATWGFPIE AIKAESDADL QKIYTSLECP VCHQFPKTGQ NIYSCKLNRH
     MICEACLPES RICPACQDTI SSEKSFAVET CISNFIIPCK YKFEGCHEII RAENVNEHLS
     NCTYRPIACV MAKCNEIVPF TQLFKHLLQA HAEKVNGIED LNTAIVEFWI EGDVNATARY
     PPFFLTCYDC VFLHMCVSTI HGTWVWCQVC ASDEEAKRFK VEMKMENIES GLSIQWIGPV
     HSVRKSVKEI IASGQVFVIN SKEIRNPFLF KKTNDHKNFW KTEVFIHQLS HKLPTQVFKY
     LETHDLKKNS LSKPRDNSWM YQVEQNPQNA AILTTKPPEP VPISGPGQTT EDIQRISSTE
     TLFKEMDAKH IAEIQGDTSQ VETVAPPEIL PVEEPPPPVN DIITEQVATL GSPEIPSSPQ
     QISLNDETET INTAEKVDDM LPTDQVTSTQ IQPQIDEAVD QIALESLPQM SSVEEIDISA
     TLDTATPAAQ ITNDDSNLLP NSEAEKPSMD GQQQENDT
//