ID A0A226EN20_FOLCA Unreviewed; 3430 AA.
AC A0A226EN20;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Vacuolar protein sorting-associated protein 13D {ECO:0000313|EMBL:OXA58191.1};
GN ORFNames=Fcan01_06998 {ECO:0000313|EMBL:OXA58191.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA58191.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA58191.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA58191.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA58191.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA58191.1}.
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DR EMBL; LNIX01000003; OXA58191.1; -; Genomic_DNA.
DR STRING; 158441.A0A226EN20; -.
DR OMA; HINIRDA; -.
DR OrthoDB; 3473362at2759; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd14270; UBA; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR026847; VPS13.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031646; VPS13_extend_chorein.
DR InterPro; IPR031642; VPS13_mid_RBG.
DR InterPro; IPR009543; VPS13_VAB.
DR PANTHER; PTHR16166:SF141; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13D; 1.
DR PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16908; VPS13_ext_chorein; 1.
DR Pfam; PF16910; VPS13_mid_rpt; 1.
DR Pfam; PF06650; VPS13_VAB; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1713..1761
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 1131..1153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1435..1454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1765..1803
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1131..1147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1767..1781
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3430 AA; 385144 MW; 033FC19E90BAE16E CRC64;
MWETFISWYI NNYLGHYVEN LNSQQLSLAL SKGELELENV PLKKNIFRSW GLPVDVKSGV
VGRIKIEFNI LKYFRNEPVL ISIEDVCLVA GPVNLAELDP LEEEALAHES KMSALDAHEG
RWKAQFDLQQ QTNNSSYYSS LYVSSMRIGA SIVTKVVENL QLNVTNVHIR FEYENEKSNH
TVAFGVTLQG LNVQSCDPKW NPLSSSSTNV SDSSFKTLRM SNLGIYCDTK AERLSDFKLE
ELKIAMCKPL SSHIYVLSPV SAEARVAKNN STLPLASLSK PRFDVHLSLE KVPLQLSDSQ
YTHTFRLYKS LRKLDRNCRL RHYRPFSNVK ENIKEWWLYA SQAVLSLRGF RRRKKLKTWD
EMLHRARDNR DYVHAYQGHL TEEVLSSEAT KLKDRMELEL HYDDIVQLRQ VAMQRIEQMN
KAPEVSGKSQ PVVEPNMTTT SAPNSTNDPG QGIQEIHGVT PTEEQQEGVK AASSGVLAWF
FPSWGYYTQA TDQPDSLTNV NSQLLHGVSS SSLADRSMSE TDFDEAILGE MRAFGQDALL
ARFNFTLNEG SVLLNKNKGP FLDLNFGGVS LELSLKPRSG SHKLQMRLSS LMLKDATTNS
CILAPHSVDP LSYLANVSAD PLFNLVYEMK PHKKAGHRVT VSTKPMDLVL YPTTWDEVGR
FFSVKDEEDY LEIPYNGYEA MKQKTKEELQ VYWDRLVHSR ISKSSGDDGR SSWEIYMDIF
APQITIYGYA TKEDGNKKTE TISRTTPQDQ PTSQESAVII DLGRFKFTNL HIDDKIVLPP
DDNKEYEEWS DDDDENEEFL TPCSSPVPER LVIEDSSLLT SPRHSVSETG ESIVYQNQTE
GIESFGGSLD KIHAIFYKKY SLEITDVQVI VFDGKSGKKT SWKTTHFKGT SMMHLVDRFS
INLQLERRLV YSEDPLWPAL TLMGTLPKLT FHLNEVKMLT LRSVLSAFST KLQNPRQDSS
DISFFSGSQL NLADTERPDF RLSETLMTRN PYKSFGNLFV AEFAIHNVSV DLQSEDIRGP
VIKVKALHLK LAKTRKHRAK EDATCELKSR CQDYFSVEGR LGSLEIQDTS LYYGLYPVKF
AFQGDQALDF DYELNGSDGK FRLNMSSIVV VHTNRFYTEF MSLWNSLFGQ PPSSAQQGHQ
SNDNDDRLSP PAEPGYNNTR VMLDIQAGAP VILLPYSSTS EKMLVADLGH LSVRNKFVED
IEGLVINYII VDLIEMDLYS GELSPRVGAA LDNRKQWNLH RGWSVIKTQD SSSFLRQQCQ
LNLKVGRVFE GNLGDSVAAT RVEGVLSTLH CTIDHEKYKL IRGLLAHNIG ENIGSPEEEP
TVMNYQQGTS NSKPHHIGTH RQGESPTKVD LNIQLDLINV TLEVVKHPGD KLGRVEFIKS
KFTFQSNNDG SKDVDLASQE IVICDSRFED IDNAREAENV NIFTNILQQS VTFPISSSSK
QQPESSSSHN PTIHGSAEVP LQAEIHYRMT QRGSNVTIIL NNMRLMVILD WWMEVRDFLG
QEIPQPPEIT AIWEEHLERT KNAHHLLERS RVVSNPVTVS TGIVTRRAPV LDLPDSVFEL
KINISNCELV AVEKASVWDT NALILKASAA LGYRPHLERP ICCNILQCEL FSCILGLESE
TALSILDPTN IQLDIVRQTE AESKGILDAT LSLANSGKIL KIQSPNLNLR LSYYDMKMFL
RLMDKFSKDA QVHFLKSSSF EIETSPLASP TNIMDDLSFQ SFATFEIDQL VLMGFTIDEA
IQALEETHGC LEDAVFFLTS TAGRPDKKIK SQSDRKTSRD NSLSAKSLAS SEAPSLPHEK
ETAGGSMSAI QGIEVKCSCL SLCVIDDCKD SDVPVLEISV QQLELYQNYL DNLTSADCVL
SGDYYNRALS GWEPFLEPWK CNVKWKKNLL GQLDDYSPSC EFPSRAPEFE IMVSSRVTME
LNVTSSLLNL YKIVSSNWTE DYHLVKNDKR RAPFIPFALK NETGSRLWFC TSISNNEEVF
RQQQKATTGC SSGTTSWTEV AHGAVQTFSF EGRGKLRHRN THQLKTHQLS IRVDGWNEIS
VSVDRVGTYF RVAKPETSLR RYGGYMELPP TRLVLEVGLQ GSAQKIVTIR SALMIKNSLP
NPVELKLENT IVYPSFERAQ TGGSMVVQVR PGASYPVPLH SVWAHMWIRP VIPDNPPRTY
LYCTKALLVG SSQEGLRECR PMSPEDQSQS YRFCAAVKRN EFPADSDDII PKNSLPSIVQ
LMSMSNRANF ITLLSPFKLV NLLPHEISYE IKRQNIHGRI PPGKHDSMSN VDTSEPIEIH
YQIDNFAQVM IVSVNPKSNT LIQRIKIQDA LKRTLMLTIK ILKEDGGVLS VQLSCPSWIV
NKSGLPLVCK QDGISGEAAG QFQEHEVGRM VTPLMMSFAD QDGSESLIFR VGTGLHKDSK
PFWCRSILCQ NGLRVRKLVV AHCNNTPQSV YMVGVEIKNG TGRYQDTKLV IVSPRFVVDN
RSTYKIQISQ RAFATSFFDA KAEKTHLTLP AGSNLPFHWP RLDKEQLLCV RLKDVAGSSW
SGGFPVDNVD SFHINIRDAD GNCYFLRVEI VIQGPSYFLI FSDTTQLPPP FRIDNFSKVP
LIFHQTCLGE ERLKITARPE SSLPYALDEP TQLAHLTIAA PGGTSVVVNM DDLRYMSHLT
YENFFYIGFT ATFPVDGSIG RSGMESLELV LDVEGVNVIL TKKEQGKRSQ LWRVSAEGLI
EHEGSSPPRD LTRPQKEGTM LVLDISGSAP LPTQCVPLQL RKPDRRRIST QHWEFTSDGK
MKCKMYENLY VQAKDGFGGT NAVGSWQLWS EVVLGPSQPV CYIRTESGIP AEQAIARQKL
RAGSGILSLG IETDGPTRVL RIIDVEHPPR RQLLHHTFEE NDYNTTPKYR VKVELPAGVG
ISVVACNPRE ELLYGRFSGF ALEWTDTKNS QILKASVMNL QVDNQLLESE KSAVIYIPSG
SPSETIDDFS LYHQQPALCL YWESMKSNLN ARVFKVWELM VKPISLIIEE RLLLKLCMWW
GFGQQVKNLD MLQQSDFEVQ KALTSTASTN TRRYYFAILK LIFNQVKLSV LTTSKLPVQL
AALKRRLGLT LIRFEDAIVD FDSFEKHHPF ETFEFLCALV VKHYRDELVS QAGIILGSTD
ILGNPLGFVN DVSEGVSLMI YEGSVGALVK NVAHGLSNSA AKVTGTLGEG LGKTILDDRH
EEERRRIKED HAGSSGEYLY AGLKGFGHGL IGGVTSVVSQ SYEGVANEGF AGLFTGLTKG
LVGTITKPAV GVLDLATGAA SAIRDSSKTS SRMIPHRLRP TRVAIGNGGL LPVYSEVSSR
GQELLFDLND KNFNELYIAC ETLKSGPNQD LRIMISSEAI TVFRPNKGNP VLLKVHLSEL
IECQMAHSAK EKTPYIELVR ILPDVQAPGR PQVICENEQV AKRVVQQVNY AKALYEETRH
SQIVVNENDE
//
