ID A0A226ENM8_FOLCA Unreviewed; 1766 AA.
AC A0A226ENM8;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=ATP-binding cassette sub-family A member 3 {ECO:0000313|EMBL:OXA58411.1};
GN ORFNames=Fcan01_07774 {ECO:0000313|EMBL:OXA58411.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA58411.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA58411.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA58411.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA58411.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA58411.1}.
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DR EMBL; LNIX01000003; OXA58411.1; -; Genomic_DNA.
DR OMA; YAIYIND; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF250; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 3; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:OXA58411.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 290..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 963..983
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1141..1161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1181..1208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1220..1242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1254..1273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1352..1369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 565..813
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1421..1651
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1766 AA; 199911 MW; F6D4DFC349B893DC CRC64;
MGIRTNNSRS WTIRHSHAPP ENVPPSRTSS WEKFRLLLWK NYKIQIRHNV QTVTEILLPL
LFTAVLLIVR NVVPSTFVKE PTIYKPITIE GHPPDIVQTS CDQIYYTPRH PVVDALMQKV
NNQYFLSQRL AYNFTGFATE EELVHAYIQS ANNSLVNSTS DFEPTAPVLA GVIFTNKFND
GSFPNDIKYT LRFPATQRSE FDLISERFGA QPVWYTELLY PLFQFLGPRA KNQIGGGLPG
YHEEGFLYLQ YAIDRTLTRE FLNSSELENY NKYDIRLQRY PYPSFIDDKY ILALQGWLPL
IIMMSFIYPA INIAKSIVYE KETRLKEYMK IMGIPNIYHV GAWYVKSQSF LVIAAGLMTL
LLKVEFFSTQ NLAIFPKADG YVVFLIFLVF TFSLICFSFF IASLFSHSNA AATAAGVLWF
VLYVPYGFLR PRYNLLPRKT KLFSCFLTNM GISFACQIIC MLEGTGVGAQ WSNIFQGSGP
DDDFSMGDCL IMMIANGVVY LISALYIEAV RPGEFGVPLP FYFPFTKSFW TSKSWTYESN
HEIETSSDVP ADFFEAEPKD KFPGIQIKGL TKIYDNGKVA LRNLSLNFYQ GEITAFLGHN
GAGMKNKLSF NSMILKSNSA IKFSGKTTTM SILSGLFPPT SGTALINNCD IRNDINSARS
SLDDDQANDR LTVEEHLRFY CLMKGCKDSN VAIEINRMIK ALGLEDKRNA QSYTLSGGMK
RKLSVGISFC GGSKIVILDE PSSGQDVGAR RSTWDLIKSE KINRTIVLTT HYMEEADVLG
DRIAVMCNGE IQCCGTSLFL KKKYGGGYHL IIVKDENCDV DKITQVIRKT IADVEVDQDV
GAELSYTLPD GKSHLFPEMF EELEDRKREL RISSLGASNT TMEEVFIRVG RKVEAKILEQ
YPQEENERKL SVSLTIDNNE LATASKTHLY NDEPLRNVGM ALKMQQLRAM VIKKLIYGFR
NRMLLMTQMG IPLLYLILIL IVVKNLPGIS NSAPHKFTLQ RYEKLGSTIT TVKCPVDEFI
CKSYKAYVLK NHLIELVGQN QSFIDYMLEK ENEDLVSVNL RYIVGFEQRQ VKETEKSEYR
QLVGFFNNQP FHAPPLSLNF ISNALLSPTN HTITITNHPF PVGSIDSLKK AGTFYTLGFQ
IGNNIALGMS FLAASFSVFI ITEKETRSKH IQFVSGLEYP LYWTANFIVD FIQFIIPCFG
TMVILFLFQI EEFMSLYMQL NLLLLFVCYG LAVIPLMYLA SFAFTVPSSG FTRLVLLNIF
TGMASILTVV MIQTREFQLE SLADTLNSIF LIFPNYALGM GIVQLSTNFQ FARDCVRFNL
EFVCPAFPSS VCCSKLKPNF LDWERTGIGK NIACLTAACC VYFVILFIWE SRVWTKFLQW
NSKIGNSSVT ADEGLEDADV VKEKKKMEET NLTQLFKENT LVVRNLTKYY DKFLAVDHIN
LGVQRGECFG LLGVNGAGKT STFKMLTGDL SISEGEAYIC SKSVRRELKQ VHEVVGYCPQ
FDALIDSMTG RETIALYARL RGIQESYIDH LTNCLGEMLL FSQYMDKRVG SYSGGNKRKL
STAIALIGSP PVIFLDEMTT GMDPVARRHM WTAISRIRDS GTSIILTSHS MNECEALCTR
IAIMVNGTFR CLNSIQELKN KFGEGYTLIA QTSPKGISES EPFTRETQEF GRRRSSHMSM
KKLRSSQGWE SELEGLRTFI EESYPGSQLK DIHPGFVHYH IPSQGVTWGS LFRKMEMAKQ
KFGLDAYSLG QSTLEQIFLA FTKAQN
//
