ID A0A226ES74_FOLCA Unreviewed; 2121 AA.
AC A0A226ES74;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 22-FEB-2023, entry version 17.
DE SubName: Full=GTPase-activating protein CdGAPr {ECO:0000313|EMBL:OXA60007.1};
GN ORFNames=Fcan01_05455 {ECO:0000313|EMBL:OXA60007.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA60007.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA60007.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA60007.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA60007.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA60007.1}.
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DR EMBL; LNIX01000002; OXA60007.1; -; Genomic_DNA.
DR STRING; 158441.A0A226ES74; -.
DR OMA; SGIWEAS; -.
DR OrthoDB; 2913909at2759; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd11835; SH3_ARHGAP32_33; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15729; CDC42 GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15729:SF10; GTPASE-ACTIVATING PROTEIN CDGAPR; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 254..316
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 387..579
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 839..899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 928..998
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1350..1382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1402..1434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1446..1469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1600..1623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1683..1719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1787..1854
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1906..1932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1955..1988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..879
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 932..948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 968..995
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1350..1364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1413..1434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1686..1719
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1787..1848
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1955..1981
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2121 AA; 233330 MW; CBB3868BC53BB169 CRC64;
MSGSMVEVMS SSTTPRMGRR SMALSDIDPK YVSQSGIWEA SEVETSRGSI RIQHLTAVSA
AAASSRASSA SMGSACGGGI SGAISSASSG ITAGGGGASN NPRFPKLEEC AHFHYDCVEL
PQLKIRIRDD PSKPISVTGD ENQDKCAFSI EVVAGGQSWA IRRTHNNIQM LDSQLHRCVW
DRTFSLLEKV HQESAVDQLQ QQHNGCWEFV TNYLARLNQL PTSAITCGTV LSWLELDNRG
RHIVSSDESA INTPAVAAAC AVKKYVAQAA DEISFEVGEM ISVIDMPPPE DSNWWRGKRG
FQVGFFPRDY VQVIGDKIPA GLPIVPSVRK LQRLSVSSSS TTSSVPDKPV LRKHGKLIAF
FRSFILSRPS RRRLKQSGIL RERVFSCDLA EHLLNTGNDI PTVLRSCAEF IEKHGIVDGV
YRLSGITSNI QKLRNAFDED KIPNLESDMA IKQDIHAVSS LLKMFFREFP NPLCTYQLYE
KFVSAAKESD QERLFKMREV VHELPPPHYR TLEYLMKHLS RVAERSSDTG MTHKNLAIVW
APNLIRCKEL ETGGVNALKG IGVQAVVTEY LIRHADLIFN DKLPTNFPTT TTVLTQKSSG
SSRPKSLAIS SPIKLMSLEE AQDKARDDRK FIDVGGGPSS LPPKYHTVID LPSSRRAGLK
NKRSPMGWKH FFSRNRSFNA SKPQRKAFTP GDITVITKNM PQPGPQGMQT NWTGRLRPLR
PVKSVESLVS PPLYNTATGS GAGHGNESSA ILRDQHSESV IMEEMESSLS RSSPATPVAA
DVVFHPLPAN SIDARCLQSK THNRSISHDS YFEFGEFRNS NNVYIDDTLE EETMSQSSKL
SLDLSGSEIG SNVTSPVKAA GCSLRSKSEE RERSRKEPFK SPITPPPSAA STMHPSDSYQ
NALSDENIVV TKRNSTATSP IFFKSQARPS KWRDSEVQTS QLKLSDVGVS TEEESGIYGT
GTRKGVDSST SMDEELGRYE LDKNSSFDES SEMSTPEKEQ FLSSISTNII YSPLVNEISS
MSSAEHINLL HSTSSISSTS TQKLSVNSNR SSKSVDDAFT TTSSANVCLF VCPLYEAGVT
NEDLIGRPAA HQDVFNQCQA ANDDVVVLVE TTNSVAQEAS SSEIADYSDL NSNTSKDLSH
IAVNNNPVEN KYENDSIGKI DELTTASNIL TTAKTIPPQS KEICHIYENE RIYQNEPVAP
SRKKLAVSSE TLSSKSSSSS VLHPNNVTTT STQLESFSQQ NQISEEKSGA VLEFEQIIMI
KPKAKEPLPL TCIDVNAAYT DCIGEEHYEN ISESHYEGNI YEDIDSESDK QQREGKYRGT
NSCRYEAVSS PPIKPSDTFA VSLSSTGCGT GGRLKDNSAP SSFYPPQDLP AEENWDDHDD
GDYESVRFQK VDDKLIPHHY SEIEEKTAST TALDDNNDDS KSGSTPSHSR TDEMITYLEV
QTPSFKLRTD SLEDNNKSEE QSSYESVGLK NSETIDDVNS PISVDEVIHF IDSPLVVENP
VYSLEMEGIN PEDIETMHKT QMQCSRGAGG AEEDDGDFDV SINESVSLSL SVEEDKSNTT
HGKPMQLKSQ NLKLLGRCNS APLTETKVDF VITDVYRQSD DRPSSTLVND QQKHQQNKNN
NDNLTLFKLP LNKRLSEPSL LQFNVNSNSL TIKTDENNAT AWKLTDAKRL ANRKSSVKEL
LSKFESRDST PSPTNTSFSN HFNTLPHVHN NNKDTQGSLV PGLPKPVSQN SLKVSVRGSG
SAVIGRNKNT DALGGFGGTG TGSGRFQHHR FSMGDILLGQ SMSESDDLNS VCSHSPSPKN
SMIRSDTFPE LRSANSRVPT ASKENLDLSA SLDRNSQSQG NLLNDNNDAS PLVPEKGAQN
ALRIAMSAVD MNDPNTRERI EKYKEERRSF LRQKITSEIN SECTQKPCIA TTTTEEGEKE
ESPSTLSPAD VESCNSEVLS NRLNANDNDS YISTISNTTR SNSSSTQVTT FTSNNKSPSD
SPRKRAFSED IPQAFSNSYF TKTKSIKTEP EFTKYSEESS TTKSTITQGI KIHEKIALWT
LQKKEISKST LSCAEISSNK SSTDSSHKPF VKPILRREVT TSSISSVELS KCKLNVARVE
NSSNGGKKIK DMAAFFEAKK F
//
