ID   A0A226ETA4_FOLCA        Unreviewed;      1368 AA.
AC   A0A226ETA4;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Intron-binding protein aquarius {ECO:0000313|EMBL:OXA60041.1};
GN   ORFNames=Fcan01_05690 {ECO:0000313|EMBL:OXA60041.1};
OS   Folsomia candida (Springtail).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC   Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX   NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA60041.1, ECO:0000313|Proteomes:UP000198287};
RN   [1] {ECO:0000313|EMBL:OXA60041.1, ECO:0000313|Proteomes:UP000198287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VU population {ECO:0000313|EMBL:OXA60041.1,
RC   ECO:0000313|Proteomes:UP000198287};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OXA60041.1};
RA   Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT   "The genome of Folsomia candida.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR038901}.
CC   -!- SIMILARITY: Belongs to the CWF11 family.
CC       {ECO:0000256|PIRNR:PIRNR038901}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXA60041.1}.
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DR   EMBL; LNIX01000002; OXA60041.1; -; Genomic_DNA.
DR   STRING; 158441.A0A226ETA4; -.
DR   OMA; RGRENNF; -.
DR   Proteomes; UP000198287; Unassembled WGS sequence.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   CDD; cd17935; EEXXQc_AQR; 1.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR048966; Aquarius_b-barrel.
DR   InterPro; IPR048967; Aquarius_insert.
DR   InterPro; IPR032174; Aquarius_N.
DR   InterPro; IPR026300; CWF11_fam.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF5; RNA HELICASE AQUARIUS; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF16399; Aquarius_N_1st; 2.
DR   Pfam; PF21143; Aquarius_N_2nd; 1.
DR   Pfam; PF21144; Aquarius_N_3rd; 1.
DR   PIRSF; PIRSF038901; AQR_cwf11; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   mRNA processing {ECO:0000256|PIRNR:PIRNR038901};
KW   mRNA splicing {ECO:0000256|PIRNR:PIRNR038901};
KW   Nucleus {ECO:0000256|PIRNR:PIRNR038901};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198287}.
FT   DOMAIN          29..219
FT                   /note="RNA helicase aquarius N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16399"
FT   DOMAIN          225..363
FT                   /note="RNA helicase aquarius N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16399"
FT   DOMAIN          443..547
FT                   /note="RNA helicase aquarius beta-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF21143"
FT   DOMAIN          635..706
FT                   /note="RNA helicase aquarius insertion"
FT                   /evidence="ECO:0000259|Pfam:PF21144"
FT   DOMAIN          716..1019
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          1028..1218
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   REGION          1340..1368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1368 AA;  158174 MW;  3D0458F5ECC96260 CRC64;
     MVKLNTATAK TRSRSRAFIP TVDAINQDKI TQLSQKYWAS NSSDPHLPFD QSVVDDLYIN
     EVVQSSFHTR RIALLEISQY LENYLWPNFD PANSTFSHIM SMVCMVNEKH REGVPVWKAF
     EGDADKFGKF IYRVLEGLLE EGSVSLKEGC SMMLFLQCAF SSLEIDLVRK QIQTLVSLHV
     WHCLSEGRRE DEFRRYPKWK KYWKSLLKKE ENENDDKKLL NQFYLLIDDL HLIVKCQMNQ
     ILEHGDGHLF SQLLDRLKFY ANFEICNESG DPMTELEVMN EHYKKITSLQ QTVFQKFSEL
     RQFALSNVNS VDTKAAIMKS FKSLNFDELK ELAGCINLID NVKKEDVSVQ FLLEALVFRY
     ERRVSQIKRL NSMALYPTEE VIWDENVVPA DYHSASGQVL ALPKLNLQFL TLHDYLLRNF
     DLFRLESTYQ IRQDIEDAVF RLKPWRAEDG STLFNGWARM ASPVVRFAVI QVAKPNLGEN
     RPSRVRADVT VNLNVRTNIK QEWELLRKHD ACFLVTVKPP NPQPPSKYDF KGDFISQVGL
     VCVRECWMLM VESLKRVLTL ALIYLVTHEL LELFWDVYET FNIFLRRKPK ENNFKCVLET
     IRDLMNINCV VPDWLHDVIL GYGDPKSAHY SELPNKLNKL DFNDTFLDVN HAIASFPNYK
     PEMKGSSTSR PIRVTFEGDD GQDSEKKVVV IEPYTILSRG PYPTNQPNLN KIQFTPTQVE
     AIRSGMQPGL TLVVGPPGTG KTDVATQIIS NIYHNFPDQR TLVVTHSNQA LNQLFEKVIA
     LDVDERHLLR LGHGEEELET EKDFSRYGRV NYVLAKRLDL LVEVEKLQKS LNVCGDVAYT
     CETSGFFFVH HVLPNWERFL IKVKAANASV EGNVEVIGQS FPFDKFFADA PQPLFKSKSY
     EQDMEIAEGC FRYIKRIFEQ LDEFRAFELL RTGLDRSRYL LVKEAKIIAM TCTHAALKRR
     ELVDLIFQYD NILMEESAQI LEIETFIPLL LQNPEQGRIR LKRWIMIGDH HQLPPVIKNM
     AFQKYGNMEQ SLFARFVRLG VPAVELDAQG RARPSIAQLF QWRYKKLGNL PHVASQPEYL
     LANPGFAYDY QLINVADFNG VGESEPSPYF FQNLAEAEYV VATYMYMRML GYPAEKITIL
     TTYNGQKALI KDIIAAKCAK SLLIGEPHKV STVDKYQGQQ NDYILLSLVR TKTVGHLRDA
     RRLIVALSRA RLGLYIFARI PLFANCFEMT PAFSILSKRP DKLHLHEREF FPTERKADVK
     FHEDPVVIKD MQHMAQFVYD IYMTKLDVYR KEEAEKKEKL LQEMRITAEA KRQEEPVPIK
     FDEDEAMNTV VTPIVDEVAS STKDQVVSEN EDDEKMEVDS TIETETTT
//