ID A0A226EUE2_FOLCA Unreviewed; 374 AA.
AC A0A226EUE2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=tRNA (cytosine(38)-C(5))-methyltransferase {ECO:0000256|ARBA:ARBA00039681};
DE EC=2.1.1.204 {ECO:0000256|ARBA:ARBA00039081};
DE AltName: Full=DNA (cytosine-5)-methyltransferase-like protein 2 {ECO:0000256|ARBA:ARBA00042810};
GN ORFNames=Fcan01_05480 {ECO:0000313|EMBL:OXA60431.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA60431.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA60431.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA60431.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA60431.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016, ECO:0000256|RuleBase:RU000416}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA60431.1}.
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DR EMBL; LNIX01000002; OXA60431.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226EUE2; -.
DR STRING; 158441.A0A226EUE2; -.
DR OMA; HYAFKYA; -.
DR OrthoDB; 197881at2759; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR031303; C5_meth_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00675; dcm; 1.
DR PANTHER; PTHR46098; TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR46098:SF1; TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00095; C5_MTASE_2; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT ACT_SITE 79
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 374 AA; 43141 MW; 57DB67B506023AC1 CRC64;
MEKIRVLELF CGIGGLHWGL KEIGVEFEIV AALEINPTVL ETYAVNFPDV RIVRRNIESL
TAEEINEMNI DALVMSPPCQ PFCRAGNKQG LLDKRSSPLI NLLQILPRIR FKYIFVENVK
GFETSDAHGE FVDMLTKIGF RYQEFLLSPV TLGIPNSRLR YYLIGKHSDL QWSFDLSDQV
LDKLPETSGN NPIQLVKDRH RQRWLNYREK RIGRHATEGK LHGSSSEKFP SKYLESATSK
SEELWYLNDI LEPNEFIFPE HKLSLEKLRK YWSALDIVTP FSTTSCCFTK AYFYYLTGSG
SILDINGNDK IESDEVRQSE GKFRYFTPRE VSRLMCYPEE FKFPSNHSLK QKYKALGNSV
NVSVVALMFA LLFS
//
