ID   A0A226EUE8_FOLCA        Unreviewed;       416 AA.
AC   A0A226EUE8;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Leucine aminopeptidase 1 {ECO:0000313|EMBL:OXA60777.1};
GN   ORFNames=Fcan01_04787 {ECO:0000313|EMBL:OXA60777.1};
OS   Folsomia candida (Springtail).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC   Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX   NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA60777.1, ECO:0000313|Proteomes:UP000198287};
RN   [1] {ECO:0000313|EMBL:OXA60777.1, ECO:0000313|Proteomes:UP000198287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VU population {ECO:0000313|EMBL:OXA60777.1,
RC   ECO:0000313|Proteomes:UP000198287};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OXA60777.1};
RA   Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT   "The genome of Folsomia candida.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M28 family.
CC       {ECO:0000256|ARBA:ARBA00010918}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXA60777.1}.
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DR   EMBL; LNIX01000002; OXA60777.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A226EUE8; -.
DR   OMA; GMLQQDM; -.
DR   Proteomes; UP000198287; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR045175; M28_fam.
DR   InterPro; IPR007484; Peptidase_M28.
DR   PANTHER; PTHR12147:SF26; ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1; 1.
DR   PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000313|EMBL:OXA60777.1};
KW   Hydrolase {ECO:0000313|EMBL:OXA60777.1};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198287}.
FT   DOMAIN          207..397
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
SQ   SEQUENCE   416 AA;  45782 MW;  C44597BFC3AEE5A1 CRC64;
     MHKSYQQFQV LDICIVIISP DISCTIKQSS KLYLVTFSSS IDKFHCNFIN MKFVLVVALG
     VALVASCPHG DEEAKAGKRL IKTTFEGPGQ WMDEDEIWGL ISKHQNFMDI TDHNFPDIKE
     GDVNVQAIPT TLRFQSTVNG LLGRTSITRM QDFIRTFSSY HNRYYQAQTG IDSQRWLFAQ
     VQESIANYAG SATVNEVTHT FGPQSSIVAR LTGSDPTLRS EIVIIGAHQD SINIAGSSLG
     APGADDNASG SVVVLETLRV LVESGYIPKR TIEFHWYAAE EVGLRGSAAI ASSYSTNRVN
     VVGMVNFDVP GYYVSGRDEI GIYTDNVNAQ VTAFLRLLVD GYCTYTWVNK TCGYGCSDHA
     SWTSYGFPAG FPAEVVFHPR MHSVGDNFAS VGFTQVNEYV KLSLGFVVEM SEPGTL
//