ID A0A226EWC7_FOLCA Unreviewed; 395 AA.
AC A0A226EWC7;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN ORFNames=Fcan01_03548 {ECO:0000313|EMBL:OXA61955.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA61955.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA61955.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA61955.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA61955.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA61955.1}.
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DR EMBL; LNIX01000001; OXA61955.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226EWC7; -.
DR STRING; 158441.A0A226EWC7; -.
DR OMA; QIATTEC; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19338; Wnt_Wnt6; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR009143; Wnt6.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF72; PROTEIN WNT-6; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
SQ SEQUENCE 395 AA; 44515 MW; 1BA4E263784554A6 CRC64;
MLELKAVESN QTKFSEQGLN NMWTNKCSSA AALRRFDATS VSAFSSSVVT QPHMPTTTHM
LIDPSRLCRK GRNKNLRDSM NFIHGKTQIA VATGGRRHRR KVRSFCNKEP EMIREAKRGS
QIATTECQYQ FKNRHWNCSA LPRSIRRVLS RDTRETAYVH AITAAGVTFS VTQACSSGQV
QDCPCDRTLS GKSTDGSWEW GGCGDNVFIG YERSKDILDI KIRRRSDIRS LMLLHNNEAG
RLAVKNNMRL VCKCHGLSGS CTLKTCWQKV PSFREIGEML KLKFDGAVQV IPGNDGKSLV
PSKASIKPPE KDDLIYFDES LDFCQYSNKT GSLGTQGREC NATSYGVDGC ELLCCGRGYR
RRRVTERKNC RCKFHWCCEV TCDTCIVTKE IYTCR
//
