ID A0A226EWP1_FOLCA Unreviewed; 4726 AA.
AC A0A226EWP1;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Protein translocase subunit SecA {ECO:0000313|EMBL:OXA61588.1};
GN ORFNames=Fcan01_00496 {ECO:0000313|EMBL:OXA61588.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA61588.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA61588.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA61588.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA61588.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA61588.1}.
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DR EMBL; LNIX01000001; OXA61588.1; -; Genomic_DNA.
DR STRING; 158441.A0A226EWP1; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.90.1440.10; SecA, preprotein cross-linking domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000185; SecA.
DR InterPro; IPR011115; SecA_DEAD.
DR InterPro; IPR014018; SecA_motor_DEAD.
DR InterPro; IPR036670; SecA_X-link_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR30612:SF0; CHLOROPLAST PROTEIN-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR30612; SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; 1.
DR Pfam; PF07517; SecA_DEAD; 1.
DR SMART; SM00957; SecA_DEAD; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF81767; Pre-protein crosslinking domain of SecA; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51196; SECA_MOTOR_DEAD; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 2718..3313
FT /note="SecA family profile"
FT /evidence="ECO:0000259|PROSITE:PS51196"
FT DOMAIN 2818..2962
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 3151..3326
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REPEAT 3412..3445
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 184..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 720..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 885..916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 944..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 428..483
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 893..916
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 955..969
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4726 AA; 530265 MW; 912A2AB33A89D43E CRC64;
MDEDGKVKKV DTSEEAIDST MTQKQSDFFL KFFICMTQSQ LEFPTNLYAL TNILRPYDLA
LSDTIDNNAW DSLISCLLQQ ATQDFVQDNF NELLPLDPNE SAQLEIELNR LKRISGEMTH
TEILEALGGK RPSLWEHIEA AMTKINATFG VNLKLMLFDG SEESKAELAR IEKLLKIEEK
VDKGDAPGDD KLGGEIKSNE IQENSIGDGK DTKIDDQELT KTKISPPKSD MADKPLIDED
DNAKKLEPAQ AKTPEMRKIS EQYVTVWFDP VGKLFHNIIL RELLYENVEE FCDALLEDIV
THEEVQNYHL QTMEPFPIAD IVPHIQQRLG LLAKIESISD LISVALPDAD PEHVSSLKKL
AQRESQVTPD SRTTSLLYRC KQQYAFGMKK ASDLIFQSHS AQHRDKLRQI IEKEEDMVRE
SDRLMDEQIA AEEEKAKREQ EIRDLEKLIA QKTGDRSDLL ALIEQKKAEL AKTAENLEIA
AGRLDYNQFR KGLSEAEPSY EVSMLNVEIS NFKKLTTLRD LVSYIYSVYN KIARPKNANL
FWKYVAANDT LSNRNELIEI IATCLQDPAR IVPNKEDFSI LEITGRQIVT SQILGQIKDK
TFRELRLVAG SIIYVDSNFE NGTWHGKNLV ISSPVVEIKG NVSIDLSGLP APAVFSSQAV
TANPGGQQLR GIFGMLAGDP LAGRSGMDGQ DGAPGESSGH FMLQADVVRN GGNLNVVASG
GQGASGQSGE HGRNGRHGYN GHNPDFGHPT EGGDFKAGVK FEAGSYGTPG QRGGNGGRAG
LESTFTGGEG GHKGNLSLPK ISHNIKLMSK VGTNGQDGRQ GGGGSGGQGG YDGVDIIWYW
IGGRLIGEWH CKRGKVRVYR RYIKGITGGL WGWWIEMSKN EQEARASKQL DGNRGNDGAT
AQQRSNQRRT ASAKQEINKA QVSILSSTIR SMYGTSAAIQ EAVTSSENEK RSLEQTQRNL
NQQKNTATAS AKRLEEEIKA ANESKDAAEN AKAQLEEMLR INLENQKQLD AAMKQVAAEK
HELAENTRKE ALISEGVGQQ VSSIFEQHSR EQVLQMRQNS EQVQQTSLVK DYVPPESSED
LDTKEIHFRT THHPEIESLY DEVRLVKNVH KLSDEFFAIA IAARSKDPGQ GGAFELGLQS
IKSFTKENKL PLYIRQYLDF QSIKLAKKDS TTTLLVEYLR DQLPQDVKVT LQTQDWLKTN
IQLRTKIFKS VNYVGDSVGE FLFRLRKHDE KNDIVAIEAE MHAIMKTLPL SSKGRILLDH
ICTIVYHHLE NWFISEVKNS LPEKAELDTR FKTFANFVDD FYRELRSVHA KVGLLRTYEV
CLAEIMKPEF NTVSGFEIFW ERAALILLDM GGNDKKDGCF CIWKNLNLLT EMLRGGSKSK
PKIEKLNIIP KLIFITDYVK LTCAQVSSLV EKCDLILAAS HGPGLLPIYD KILELKHKFY
SRYVDTIQKP ALSRITAFTD GIGDKGQQRE IHAQIEDVIS NIIEANASPL SLQHRQHFYE
RIEESVQSVG DKKTGVNIVI KDIHSSVRSF KPASNLDKLQ DIAYIITNGT DFRTDFNQAL
STLTSYLGTQ SETKLSPEFI IGLNSWLKAV TMSLLLLQDG VQLDELIMVG KSIGDFIRKN
LYLSSYGNFL IRDTIRDLQL VLSKKMTLST FLKQKEVYEK GDKSIDECVE LKVQIVKFVE
NYLTASDEVV GLEEITASVD MHLDKIFVAM LREGKGDEVA ALYSSILNKL EGSKSTAGEF
LGILANVINA ATTNAVTLKI SALSTSSFVQ EYNRDPFDIS NFEKLLNHCV TNILATPSDF
TPIIEYLLQA FVAMQVMNPK NYQISAQSNT EFEKLCEILA KILSSLTDTF EKHQSNLSLD
VMHHLDNLQN LVVSVAERDN STLAEFLREK LEDFQGKRET NFNKKRTQLL SRFDDLVQVY
SDSEHGVLSF TGVAEVFLTE GMVKFVKICG TLNNMTEKEG HEFDQLYFES LLKYFNLQAI
PTMPTNLRAD VFHLVATKGA TQLGNVLNTF HSLIEAPSQE TDWIMTFLII LNKLIVSIPT
EKVTCVQLEG TLHMLDKCHG EIERSELKNK CIPQINDIQA SITSLSRRII ATKGGDPLAA
LISQDVDVLS CISPNLGQCL KLQCKLFSLL ENHSSANIFN SHLRTIVDAA LKSTLGVNIP
PVGGNECLVA LRDLKNPHVW KSILAVASIS VKINLNESSF LGRVATSGYS ATWEPSITQI
NDLVDSCIKT SSTNDLAPDD GNRFIFAFLD EDVTGSCIFS DILTSHEKQW IELIFSFSHS
KQHGLLNAAI CDIFVNTGAP GWNNELESLA YTTLFGKFVA EYKPLFSETL GQIKPSVSAQ
SFKTLQEEVT IFLQSHKEVL RNREALQLSS SSLIAHRQAQ DAQGNTSHEV QEHISTIKHF
VEQFIVLKYN FNRSIFFAGA EGHGSLWFEW MRLLHQRCTL RKLPLPEFNA LLQRSVDLPV
PKLVSLISQT TMEHWLETIY FHIAVQNYIT YLNNKEKASV GKTMDVESNV TEMTTLLKAL
KPTPFLKRFL LMLGDKIMME IQLAEISGAT PLELDKFVAV ISDLTRIVIS DKLIDNLEKH
GISQWAISVR EHVLLQIWPP QVATVILKLE GTIGKDIVSE FVGLFEKKFP GKHEVLVTLL
EKFVSRRLIL DEEMIISFKR KTIPSTTLPD WESWLAAHAV EINKRFRDVH ELARLMRNDE
KNQDIKLMLN PQGDTCKMEV IVVKVNALLD QVCKIAPPIL TPIGTWQTEQ IINWAVTIRS
FSEQERRQIV EKNKTEVLAV LCQALRVFTS KTNPTTGSLE KPGFLPRDTQ LASVILLIDA
FYARMGRLAE ISTGEGKTFI TAMMATFHAL AGDDVDVITS SPILAVENVR EVTGYFSLFG
ISVTNNCDKE CEQHERARKE RYQCQVIYGD VGSFQRDILL TKLFDKGITM NRTTETVIVD
EVDSMLLDKG ENILYLSHSI PDLKHLWPLM IEIWQATHGP DVLQGRRQDI SLVVCFIRER
MRSGDIFMPN RLRNFVERRL PIWVKNAFIA EHLLENDPYI VADLDKRGTK VIIVDKDTGV
EQVQMHWSNG LHQFLQLKHG DRVTPESLKA VFMSNIGYFQ QFRGRLYGIT GTLGSFAERH
LLTECYGVDF FSMPRFKASK AYEEDGLIGR TNKEWLDLIS QEVHQKTKTD SRAVLIICEN
VASVDKIAEK LKETVSSGKM YSYKSSFDEE FHRKNRSSPL SAGDVIIATN LAGRGTDLKT
SLELEQAGGL HVILSYMTGN IRIEVQAFGR TARAGLSGTV QFIIRDPTAD TKNPVTIDQL
RQLRDMKEAE RLENFRTKSM QRIEIEEHLC SKFNTLYANV ATYLKSSGLP QEYKDLQLEF
LKNQWALWLD SISEQIKILH ITGRSRILEQ FSDFERTAMT NISRFGSFAT GALEHTKLGR
YYQSKEEYGR AISCFDMAIN SEPNYAEISH YYKAACILKE NMSGMTHKRR AIYHLKSSES
VIRKRIAQVM TASQTLDVTS SIRREAGVGT GSNRFEKQVK SESELYQVHV GKIQEAIGST
VDAKFFENIT GVNSEQEGEE IFACLRRHYN IVKSFRLSRK IRIGGDNKIY IPDGATGQPI
EVEWPNAFRY CRDEIVNFLR ERLGMNGSSR VIEPEGFSYF IQTQTSFWTM LGGYGFFENE
VQARIQMVNE NLDGLVVPER LMDYKNSLTK ILGGKSNQAF SPDMLSPLGL MANDLQEVID
ALVKVGILVW KTTYSAKLSS AMKDKLKWNA TKGKFEGIPA ALQKYEDIIQ AIIEDAPSSE
DDYVNPDKST PSLKLELSLT DIPLPDTAQF GSRQLWGALN ESGVIKDCKV NFQTRLADNS
GRISDRLEEI QEAIEDLPEL KQIYKRYNGS GDSPSIDDVM EAIKTTIGNI KIFPDISVDY
QKLEEYFRTG EYPPEIEEFR YMVFLQVLEC TEYKSWWDWG AFIVAMLGVA QIIAGVLLEV
FTAGIGTYIA GALISEGVGD IAFAIEAGLS KNFSWKSYRD HKIISVCISI VTCGVGAWLS
KGAQVSRFAG KAGFQLFKAV ALRVIKKAGQ AVLFKLIDIG IDKLLEHIQT QAIKNCGSQL
ESLFLSDPGI KSQLAELQHK MDFVYQHSYE PGQAEKVIRD GLTRVLADMQ GEGFGVKMGE
IASKVTSGMA SAIGKASGKL LTHGKRVAEN MESGNSFLSK AAKLAQIAEV IDKVIKGGEI
AKQLLELVNL APQVLTRLCR HLEMQGINLK TVGKDKIKNR NDSGQFVQFK SEFTKSTKDE
LVKMLLSKVN SGLVAPAFQD LTQSALKKAG KAVEKNTKAI LHSLRTPKEE EIKILKTLRR
REALNEPEIA GKIKGKIYLE ELDPATPIKN ADGKSIQQLR ECYGDSISVY KDQMGKFHVE
RPSFEDSIKN FGQGRKAGFY ELMICAKYYG QTVEISDLSG ELETSGTDGK VRIHPDGTPT
KDRPPLRMAY QKGENGFGYF SPIVNDEIVP LSRSNSDTIN TNLYQSLNFL AGEKNVKFRT
EEWDKLMVEA CSKDKVKGSL ANISKYAGAD KTAKFLYETG AYEVGNDKLW QKSKAAKLTG
ITSPSRFDRR AKLPGLDNMD NMTVQTWKGN SLDIVVVGDT FAVLEKPTTI VKQASFEMPN
LDPAIDAYIK ERDAKIEKRL NRAVSQYLKA KWETQSDMKF GESRVQSSGM DHPELENLTG
YPSSLVRART LRDSAQNNFG RIASSRLSDD FNLPVMEFKV HGKSTA
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