ID   A0A226EZ91_FOLCA        Unreviewed;       910 AA.
AC   A0A226EZ91;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=DNA repair protein RAD50 {ECO:0000313|EMBL:OXA62488.1};
GN   ORFNames=Fcan01_03783 {ECO:0000313|EMBL:OXA62488.1};
OS   Folsomia candida (Springtail).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC   Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX   NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA62488.1, ECO:0000313|Proteomes:UP000198287};
RN   [1] {ECO:0000313|EMBL:OXA62488.1, ECO:0000313|Proteomes:UP000198287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VU population {ECO:0000313|EMBL:OXA62488.1,
RC   ECO:0000313|Proteomes:UP000198287};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OXA62488.1};
RA   Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT   "The genome of Folsomia candida.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the SMC family. RAD50 subfamily.
CC       {ECO:0000256|ARBA:ARBA00009439}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXA62488.1}.
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DR   EMBL; LNIX01000001; OXA62488.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A226EZ91; -.
DR   STRING; 158441.A0A226EZ91; -.
DR   Proteomes; UP000198287; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR   GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038729; Rad50/SbcC_AAA.
DR   PANTHER; PTHR18867:SF12; DNA REPAIR PROTEIN RAD50; 1.
DR   PANTHER; PTHR18867; RAD50; 1.
DR   Pfam; PF13476; AAA_23; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          8..229
FT                   /note="Rad50/SbcC-type AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13476"
FT   COILED          148..185
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          210..237
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          398..425
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          591..625
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   910 AA;  102331 MW;  4E0BE2DBB696786F CRC64;
     MEVKLKSLKF YGFRTFSDDS EVHEINFDKK LTIIHGRNGS GKTTVVEILL FCMTGKLSSN
     PDGLDSFVTG VPATITLTFI KGSDTYEIKW TLNRPNVKIM ATCQIKENRT EAEEIIRKIL
     DVPAGAVEKL ILVPQENTLW AFNTPTNLKE VLDKLLNLEE DNKQLMKLVE AKKEIEKRMK
     TAEIDLTVAQ GAAEKHPSIV TEEAATSRKE AELQAVVTQL TDEIEEMLNK HEKYDKVLKL
     GEDLDRLKSC ADSLNISEEE IDTLDEKELE YDLARVDAEL GDKLSTIMRK IREKDDLAIQ
     LQDTSEQLGH AKANLENSEV SLAQILEYCS QYDSPDVESC KGVIQAKITK LQEDLEQINI
     RKEKVEVQNR LDSCIKLEQM ALNFEKFKKM SDQKWTTLLQ LERDIAKVEG KIEAGQENVD
     DFERLCPDET ILMAELNGRI LLLKRNLKYL TAQLATKTAT FDEMETQFFD ELKFDPNLAS
     VVQSQNNGSR DYPLPAKIAR IDESLLSNDS KSQNKFSQIA TEKSTLLQKL GGLNSRLIVD
     ETTEDIKPQL DDELFKLKMA FGQIENLQRL SVARNNGEGT HLMVDAFNAS CEILREQAAQ
     KEIELKELEI VIHDVKKKKE KIQFKREKAI PCISQIREIK TALATATQTL ISCSLESTQV
     STHAGQLFDQ ITQKTTTLEN AKEKSATASG ELNEIRKALA TSTANVAACK IHEEAMSNLV
     TGYKIADTVA SAKRHQILTK HQEMVAEINQ YLADKWESLF PYDDIPSISL SQVEIKHEGV
     RRVDYNYHFN MDTSADGELK MRGRSSHGEK ILAALIIRCA LAKKFGPNCE ILAFDEPMGG
     LDGDMGRGLV DHFSSITDKT QVIVTTHSLE FAKALVSKGN AVGEEVGFYR VEKEGGRSKF
     HEGFGDLLDD
//