ID A0A226F0N9_FOLCA Unreviewed; 632 AA.
AC A0A226F0N9;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Beta-1-syntrophin {ECO:0000313|EMBL:OXA63333.1};
GN ORFNames=Fcan01_03110 {ECO:0000313|EMBL:OXA63333.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA63333.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA63333.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA63333.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA63333.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the syntrophin family.
CC {ECO:0000256|ARBA:ARBA00010798}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA63333.1}.
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DR EMBL; LNIX01000001; OXA63333.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226F0N9; -.
DR STRING; 158441.A0A226F0N9; -.
DR OMA; RAETCKD; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR041428; PHsplit_syntrophin.
DR InterPro; IPR015482; Syntrophin.
DR PANTHER; PTHR10554:SF12; IP02644P; 1.
DR PANTHER; PTHR10554; SYNTROPHIN; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF18012; PH_17; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287}.
FT DOMAIN 112..195
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 334..478
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 66..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 567..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..589
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 632 AA; 69488 MW; 558AE58C7846D56F CRC64;
MKMETMESTR SNTSTGTGGW SGGHSTLGAG RCGPLEVLIK NQWHRVLASL EGQYISLSLY
ETEANSTTTT NGHSNSNSNN GTSSNTPTPP EQNGHDFGNS NGNEGMSCEV RLVRVVKTET
HGLGVSIKGG RENNMPVIIS KIFKGMAADQ TGQLFVGDAI LTVNGEDLHN ATHDEAVRSL
KRAGKTVELE VKYLKEVTPY FRKASLLAEL GWDLQKEYMA NGTTCTTSPE DNGGRAEEPL
GLPGPAPDCS FGRCDTRAVP LTLAFLATNY RHPDLDHRTM ELYAPDGLHS LVLRAGSMAQ
CQAWVSGLSH TLSDSTQVAL QRANRYVQGL LEGKVRHMGW LLKRNPPASE QQHGHQSHGS
ANNSIKSRSQ STSSDGDDAS NLWQPNFVVI TDKELRLYNS PPWSIDAWAN PYDSWPLLTT
RLVSSSSRSQ STSPAGLRDF LTFHIRIGTP SGVVNVIFRT ETQKDLAGWA RNIVVSSHEA
ANSQKEISCK CSWKNEPCQL KVHYDEGFTL SELPKGEGGG PPKVLWQYSY TQLRTSADDA
NHLLWLDFGA EDGEKVQQQH YELDLQGCPK PLGRGGRVPP VPPPKPRARR RSQPQQELQD
DIQQQNNPFV NNHRRFHSNP RVRSNSLSGH VA
//
