ID A0A226F102_FOLCA Unreviewed; 700 AA.
AC A0A226F102;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=N-lysine methyltransferase SMYD2 {ECO:0000313|EMBL:OXA63452.1};
GN ORFNames=Fcan01_01033 {ECO:0000313|EMBL:OXA63452.1};
OS Folsomia candida (Springtail).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Collembola;
OC Entomobryomorpha; Isotomoidea; Isotomidae; Proisotominae; Folsomia.
OX NCBI_TaxID=158441 {ECO:0000313|EMBL:OXA63452.1, ECO:0000313|Proteomes:UP000198287};
RN [1] {ECO:0000313|EMBL:OXA63452.1, ECO:0000313|Proteomes:UP000198287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VU population {ECO:0000313|EMBL:OXA63452.1,
RC ECO:0000313|Proteomes:UP000198287};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXA63452.1};
RA Faddeeva A., Derks M.F., Anvar Y., Smit S., Van Straalen N., Roelofs D.;
RT "The genome of Folsomia candida.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXA63452.1}.
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DR EMBL; LNIX01000001; OXA63452.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226F102; -.
DR STRING; 158441.A0A226F102; -.
DR Proteomes; UP000198287; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd20071; SET_SMYD; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR47332; SET DOMAIN-CONTAINING PROTEIN 5; 1.
DR PANTHER; PTHR47332:SF4; SET DOMAIN-CONTAINING PROTEIN 5; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:OXA63452.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198287};
KW Transferase {ECO:0000313|EMBL:OXA63452.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT TRANSMEM 321..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..55
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT DOMAIN 64..177
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 675..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 700 AA; 79674 MW; 46D908A18B410BC3 CRC64;
MSTQPSRHCA YCLVLMLPEN VKVCGKCRRR AYCSVECQTS DWSVKGDGQR HRKWCDLNCG
EEDLDWKVVP VPGKGLGVIA LRQIPAHSRI MVDGWRPLGT RLINDLEPAE GSLEDKINVN
SFHIEEFTAS IICARMARVN HNCAANAFHL TGTESRVKIL FSLKDIEKGE EICISYSWLD
DPRFANDPVP TDGIRRALEQ DYGIVCPLDC ICRDEEIQTL AKERNQLFER VNDWAESDSK
APPSVLSSVI SAVKRLVEIS EIVPVLSMRI ADCLLNGYYA AKMKRDNRTA KQFLKRCKTL
MELMYHPESE KIKRLVDLEE YIIGAIIIII TLIFGWISIK TKILDNQCKI TVSSQCTERD
ITLARINLQE AIHKNNTQET VAILQDKTKR ERIISKHDLK GREIVLESQG QNAILERERL
QQAGITNRTQ IKTQAFTNVA NMDLTFRYRE LDYDKQKFNA MLDFNGAVLQ HQDQWNERDL
SIKRELGLEQ GRTHRYLADR RQDAIEFSQR AESARHLTSM NTYKDVTLTQ LKSAEKMTKR
TLETEMAMQD RSLNWEKERF EAQHELNGRM LELNDNWTNR SLDISKMAIE NQAEMHSLEM
DTCRGLGLAS LSVNRDLGMA SIQSNERIEF GGFDCRRDEA REATKQAESN SNFLQDVLGT
TLTVLTGGLF SKGNGGNGGG MRALPSPGSS SRRAIVQPNF
//
