ID A0A226ME72_CALSU Unreviewed; 594 AA.
AC A0A226ME72;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 22-FEB-2023, entry version 12.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN ORFNames=ASZ78_000003 {ECO:0000313|EMBL:OXB53575.1};
OS Callipepla squamata (Scaled quail).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Odontophoridae;
OC Callipepla.
OX NCBI_TaxID=9009 {ECO:0000313|EMBL:OXB53575.1, ECO:0000313|Proteomes:UP000198323};
RN [1] {ECO:0000313|EMBL:OXB53575.1, ECO:0000313|Proteomes:UP000198323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texas {ECO:0000313|EMBL:OXB53575.1,
RC ECO:0000313|Proteomes:UP000198323};
RC TISSUE=Leg muscle {ECO:0000313|EMBL:OXB53575.1};
RA Oldeschulte D.L., Halley Y.A., Bhattarai E.K., Brashear W.A., Hill J.,
RA Metz R.P., Johnson C.D., Rollins D., Peterson M.J., Bickhart D.M.,
RA Decker J.E., Seabury C.M.;
RT "Disparate Historic Effective Population Sizes Predicted by Modern Levels
RT of Genome Diversity for the Scaled Quail (Callipepla squamata) and the
RT Northern Bobwhite (Colinus virginianus): Inferences from First and Second
RT Generation Draft Genome Assemblies for Sympatric New World Quail.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXB53575.1}.
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DR EMBL; MCFN01001141; OXB53575.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226ME72; -.
DR STRING; 9009.A0A226ME72; -.
DR Proteomes; UP000198323; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR039919; ARHGEF10/ARHGEF17.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR12877; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR12877:SF15; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17; 1.
DR Pfam; PF19057; PH_19; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198323}.
FT DOMAIN 83..271
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
SQ SEQUENCE 594 AA; 66959 MW; DA76EFBC67F4DB59 CRC64;
MLQMVRTLAQ FTIALEDMRD IGDGIDAAFT AASGLGGATE ELPEKGRGGP EPLCRHRRGH
LRVSGPHCHP DFIWVFSPPA QDMRKHVIMT LLDTEQSYVE SLRTLMQGYM KPLKQPENSL
LCDPSLVDEI FDQIPELLEH HEQFLEQIHD CVQNWHEKQK VGDLLVQSFS KDVLVNIYSA
YIDNFLNAKD AVRIAKEARP AFMKFLEQSM RENKEKQALS DLMIKPVQRI PRYELLVKDL
LKHTPEDHPD HPFLIDAQRN IKQVAERINK GMKSAEEVER NARIVQEIES HIEGMEDVRM
GILARGPGWG WLQAPLRRFL RQEMVVEVKA VGGKKDRSLF LFTDLLVCTT LKRKSGSLRR
SSMSLYTAAS VIDTASKYKL LWKLPLEDVD IIKGASQATN RESIQKSICR LDEDLSTLGQ
VSKLSETLSF PHQSLDDVIK DLMAAIHREL AEKQSLSFSM AFPPNKVELS AAKADGTESF
IFEFPNPDAR LGFEQALEDA KKKLASSKNC LDPEFLKAIP IMKTRSGMQF SCASPSHSSP
ENAHEVWVCN SDGYVGQVCL LSIRKEPIVE ACIAVCSARI LCIASVPGLK RPYR
//
