ID A0A226MLU1_CALSU Unreviewed; 1618 AA.
AC A0A226MLU1;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=ASZ78_011704 {ECO:0000313|EMBL:OXB56120.1};
OS Callipepla squamata (Scaled quail).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Odontophoridae;
OC Callipepla.
OX NCBI_TaxID=9009 {ECO:0000313|EMBL:OXB56120.1, ECO:0000313|Proteomes:UP000198323};
RN [1] {ECO:0000313|EMBL:OXB56120.1, ECO:0000313|Proteomes:UP000198323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texas {ECO:0000313|EMBL:OXB56120.1,
RC ECO:0000313|Proteomes:UP000198323};
RC TISSUE=Leg muscle {ECO:0000313|EMBL:OXB56120.1};
RA Oldeschulte D.L., Halley Y.A., Bhattarai E.K., Brashear W.A., Hill J.,
RA Metz R.P., Johnson C.D., Rollins D., Peterson M.J., Bickhart D.M.,
RA Decker J.E., Seabury C.M.;
RT "Disparate Historic Effective Population Sizes Predicted by Modern Levels
RT of Genome Diversity for the Scaled Quail (Callipepla squamata) and the
RT Northern Bobwhite (Colinus virginianus): Inferences from First and Second
RT Generation Draft Genome Assemblies for Sympatric New World Quail.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXB56120.1}.
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DR EMBL; MCFN01000671; OXB56120.1; -; Genomic_DNA.
DR STRING; 9009.A0A226MLU1; -.
DR Proteomes; UP000198323; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01093; CRIB_PAK_like; 1.
DR CDD; cd06659; STKc_PAK6; 1.
DR Gene3D; 1.25.40.430; -; 1.
DR Gene3D; 3.90.810.10; CRIB domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR013212; Mad3/Bub1_I.
DR InterPro; IPR033923; PAK_BD.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR035066; STKc_PAK6.
DR PANTHER; PTHR48015; SERINE/THREONINE-PROTEIN KINASE TAO; 1.
DR PANTHER; PTHR48015:SF19; SERINE_THREONINE-PROTEIN KINASE PAK 6; 1.
DR Pfam; PF08311; Mad3_BUB1_I; 1.
DR Pfam; PF00786; PBD; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00777; Mad3_BUB1_I; 1.
DR SMART; SM00285; PBD; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51489; BUB1_N; 1.
DR PROSITE; PS50108; CRIB; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000198323}.
FT DOMAIN 81..240
FT /note="BUB1 N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51489"
FT DOMAIN 1045..1058
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT DOMAIN 1355..1595
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 453..519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 581..611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1260..1330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..265
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1261..1276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1287..1324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 1384
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1618 AA; 181713 MW; F4E411D671D09A58 CRC64;
MRERLATVGG LDFPAAAGPP QSRERGAQSS KMAQDCEDEW ELSKENVQPL RQGRVMAALQ
EALAQQDTST HTAAQLRKQE FESEIRFYSG DDPLDVWDRY IKWTEQTFPQ GGKESNLSAV
LERAVKALNK QQRYYQDPRY LSLWLKFGNC CNEPLDLYSY LHSQEIGTTL AQLYVTWAEE
LEARGSFKKA DIIFQEGLNR KAEPLDKLQS HHRQFQTRVS RQTLLGLEEA ADEKDTALLG
AEEPQRSTLA DLKGRGKKKV RAPVSRVGDA LKAPNQNRSF QALTSQQLSN NPGFAVFDEN
SASASGPEIP VLTSQHWTEP PAPRAKENEL SAGPWNSGRR PRSSANSGVE VPCPMPSFTP
YVEESAQQQV IARKPEKEED PLQRVQNHHQ DTQEKKEVVM YCKDKVYAGV EEFSFEEIRA
EVCRKKAKKK AEEEMQTIAQ KKEEIQKKIE ELEKKLKEKG NDKQQQLHEQ PTEVTKPSAP
LGVQEPLFSS GTELGVKQPR LQSESCLSEY DQPREPSCSE EVIKSLGACL DMEKGSVFSD
SEDELEKQRE KANLVKRDAV FLPPPDPAPF FSILDESSAS ANQNISRSTE NAQKTTRRPL
AVRKPSDSAV AKENLPPEYE VHGIEPLTED AIVTGSYKHK SLCANPEDTC DFVRAAHLAS
TPFHGVAAQR IPAPAYSHVV LKEDCPEPKS APLNEKTPVC EGTYSEALCV NKLSPIMEAS
LEDTRLSGSS VSSGSSLSSV TQISTIKYLH EKLELAQSLP AEPISDAGGT SEIITGDDVT
QFLWTAEQRK KLLDPMPESL TASPHFHLEA GSLPVIEFEK DVELGNETYC IKWEYWTDEE
YKMLFAIPAN FPQLDAKGFA IKVYSQPVPW DFYITLQLHE RLNADFDQSF SDNCSCFLYR
DGCAVLHRDI NRFTLEADLV GIADIVHLML FGDHIQVHQE NSVWKISQNA SRSVGCDFWG
KFFLQVLNAD DWRFLFSQKQ NEGGSYLGNV ASESLIRTVG GEGGFVKVNG WANTRECTTV
LENTQLSEID KGIMFRKKKK KRPEISAPQN FEHRVHTSFD PKEGKFVGLP PQWQNILDTL
RRPKPVVDPS RITRMQLQPM KTVVRGSTVE VEGYISGILS DIQKLSAISS NTLRGRSPTS
RRRAQSLGLL GEDRPPDMYL QSPEADWADK YGNYLNCNGG TKVTRRQTMW PDYKPRLDGE
THPNGMVTKA QSLGPSEFQD ADSSCLQRAS CLQHMPALLG ESDKMGKRSL EDCWPQPCLV
RQANSRPSGE GSPSSKSREN SLKRRLLRSV FPSSSSSNKS GPSLHIKTSS SNLHLPQDSS
GKGQPASEDP VVVTHEQFKA ALRMVVDQGD PRTLLENYIK IGEGSTGIVC IAREKHSGRQ
VAVKMMDLRK QQRRELLFNE VVIMRDYQHV NVVEMYKSYL VGEELWVLME FLQGGALTDI
VSQIRLNEEQ IATVCESVLQ ALSYLHSQGV IHRDIKSDSI LLTLDGRISK DVPKRKSLVG
TPYWMAPEVI ARVPYTTEVD IWSLGIMVIE MVDGEPPYFS DSPVQAMKRL RDSPPPKLKN
FHRTSPVLRD FLERMLTREP LERATAQELL DHPFLLQTGL PECLVPLIQQ YRKRTSTC
//
