ID A0A226N951_CALSU Unreviewed; 944 AA.
AC A0A226N951;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=LEM domain-containing protein {ECO:0000259|PROSITE:PS50954};
GN ORFNames=ASZ78_013453 {ECO:0000313|EMBL:OXB64027.1};
OS Callipepla squamata (Scaled quail).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Odontophoridae;
OC Callipepla.
OX NCBI_TaxID=9009 {ECO:0000313|EMBL:OXB64027.1, ECO:0000313|Proteomes:UP000198323};
RN [1] {ECO:0000313|EMBL:OXB64027.1, ECO:0000313|Proteomes:UP000198323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texas {ECO:0000313|EMBL:OXB64027.1,
RC ECO:0000313|Proteomes:UP000198323};
RC TISSUE=Leg muscle {ECO:0000313|EMBL:OXB64027.1};
RA Oldeschulte D.L., Halley Y.A., Bhattarai E.K., Brashear W.A., Hill J.,
RA Metz R.P., Johnson C.D., Rollins D., Peterson M.J., Bickhart D.M.,
RA Decker J.E., Seabury C.M.;
RT "Disparate Historic Effective Population Sizes Predicted by Modern Levels
RT of Genome Diversity for the Scaled Quail (Callipepla squamata) and the
RT Northern Bobwhite (Colinus virginianus): Inferences from First and Second
RT Generation Draft Genome Assemblies for Sympatric New World Quail.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ANKLE2 family.
CC {ECO:0000256|ARBA:ARBA00007597}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXB64027.1}.
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DR EMBL; MCFN01000134; OXB64027.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226N951; -.
DR STRING; 9009.A0A226N951; -.
DR Proteomes; UP000198323; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd12944; LEM_ANKL2; 1.
DR Gene3D; 1.10.720.40; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011015; LEM/LEM-like_dom_sf.
DR InterPro; IPR035006; LEM_ANKL2.
DR InterPro; IPR003887; LEM_dom.
DR InterPro; IPR011320; RNase_H1_N.
DR PANTHER; PTHR12349; ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR12349:SF4; ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF01693; Cauli_VI; 1.
DR Pfam; PF03020; LEM; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00540; LEM; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF63451; LEM domain; 1.
DR PROSITE; PS50954; LEM; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Reference proteome {ECO:0000313|Proteomes:UP000198323}.
FT DOMAIN 79..123
FT /note="LEM"
FT /evidence="ECO:0000259|PROSITE:PS50954"
FT REGION 51..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 558..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..781
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 783..816
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 858..899
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 944 AA; 104441 MW; FB10844841A61427 CRC64;
MERWAGAAGG GWSSLWDGGW DRWPAWELLA ACALIGAVGW LLRLLDARTG GRGPPREDLS
VPAPRGESRP GEVTMDAILS RLKQLSPDEL REEVIRAGLK CGPITSTTRF IFEKKLAQFL
LEQQRALEEE GSAWSEEAAG SSPSDGTHTA VKNAAVNHSH HGSASEDADF GYCVGLNPPE
EEAVMHVDCS APACGAGYVG SQGSTQTASR DPPLYYGVCP VYDDILARNE RIHVYEDKKE
ALQAVKMIKG SRFKAFSNRE DAEKFAKGIC DYFPSPSKSS LCSSPMKTGS FNRGCRYNVM
HVAAKENQAA ICQLLLDTLE NPEFMRLMYP DDDDTMLKKR IRYIVDLYLN TPDKAGFDTP
LHFACKFGNL DVVNVLTSHP AIVKNPRNKY DQTPAEVVCE RSKNKSAELK EKLREYLKGR
YYVPLLRAED NSSAPVIGAP WSPDQTDDSP QAALPKYPGS PKDPVLSIRA FAGPMSPSKA
EEFRRLWKTP PRERAGFFHN VRKSDLERGV ERVGRELAHE LGFPWVEYWE FLGCFVDLSS
QEGLRKLEEY LSHREMSEKA QQGTGENETC NRYKTPQPSG KSKKCCNSIS VGAFLDEDDD
DMSLEEIKNR QNAARNNSPA AMLKEPSINT IGDSECEILS MEHSRSIIET SAEPRHYEKG
GSSSKNGFCN PVASERIIGD RKHVHDGEDC LVSPVCSLMS EFESLTFQPQ ADAGESNNIT
EKMRNERILP ERTSQGRMPK GRQDKTCYAA SLTSSSEPSV TGGPRETKLR TEHKMPSERE
RLSMESGIQT NEARQCQEPP SQKFLLKTSP TNDNSKKLFL LGERPSKLDS DVLAAVEAVQ
IDPQKYPAVY RWKHEVQSYS SSDRQSWPSP ALKGRFRSQS TAAGPPTASV YSSPGRNSPV
PGSPGKHGSA ASFSPDPGSP GRYSPASVNH SMLKLRYFSE PPAL
//
