ID A0A226NDY8_CALSU Unreviewed; 927 AA.
AC A0A226NDY8;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=VASt domain-containing protein {ECO:0000259|PROSITE:PS51778};
GN ORFNames=ASZ78_004439 {ECO:0000313|EMBL:OXB65763.1};
OS Callipepla squamata (Scaled quail).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Odontophoridae;
OC Callipepla.
OX NCBI_TaxID=9009 {ECO:0000313|EMBL:OXB65763.1, ECO:0000313|Proteomes:UP000198323};
RN [1] {ECO:0000313|EMBL:OXB65763.1, ECO:0000313|Proteomes:UP000198323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texas {ECO:0000313|EMBL:OXB65763.1,
RC ECO:0000313|Proteomes:UP000198323};
RC TISSUE=Leg muscle {ECO:0000313|EMBL:OXB65763.1};
RA Oldeschulte D.L., Halley Y.A., Bhattarai E.K., Brashear W.A., Hill J.,
RA Metz R.P., Johnson C.D., Rollins D., Peterson M.J., Bickhart D.M.,
RA Decker J.E., Seabury C.M.;
RT "Disparate Historic Effective Population Sizes Predicted by Modern Levels
RT of Genome Diversity for the Scaled Quail (Callipepla squamata) and the
RT Northern Bobwhite (Colinus virginianus): Inferences from First and Second
RT Generation Draft Genome Assemblies for Sympatric New World Quail.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
CC Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004389}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXB65763.1}.
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DR EMBL; MCFN01000082; OXB65763.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226NDY8; -.
DR STRING; 9009.A0A226NDY8; -.
DR Proteomes; UP000198323; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044232; C:organelle membrane contact site; IEA:UniProt.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR23319:SF3; PROTEIN ASTER-B; 1.
DR PANTHER; PTHR23319; UNCHARACTERIZED; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF16016; VASt; 1.
DR SMART; SM00568; GRAM; 1.
DR PROSITE; PS51778; VAST; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198323};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 816..836
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 565..736
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT REGION 1..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 740..760
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 927 AA; 106242 MW; 9FB722071348FBE1 CRC64;
MRRMKNVQEQ SLEAGSYQDS PSSSKEYLQL PSIEITPSSD EDTPWSNCST PSASPRRKRF
LLRKWLRVRE KKECSESSSQ QSSQQSSHDD DSSRFLSPHT RDDSTASNSN RSTPACSPIL
RKRSRSPTPQ DSQGDTMVEK GSDHSSDKSP STPEQGVQRS CSSQSGRSGA KNSKTGCLLH
GDSSLGDTKE DYGPEISGEV EDAGVEWQSP AGLAESDGFS WIVHAWRVWP GMGKCIRKAR
VGIMVESYLK IIPGVKCIWF DAGVLCALGR KRAFCYLQVL SPTYKQRNED FRKLFKHLPD
TERLIVDYSC ALQRDILLQG RLYLSENWIC FYSNIFRWET LLTVRLKDIC SMTKEKTARL
IPNAIQVCTD TEKHFFTSFG ARDRTYMMMF RLWQNALLDK PLCPKELWHF VHQCYGNELG
LTSDDEDYVP PDDDFNTMGY CEEIPVEENE VNDSSSKSSM EAKPEASPQL PKKSVTASTL
TSTGSSEAPA SFDGVLPEEE EAVAESPVEK DLGIANIMGE KIEIIAPVNS PSLDFNDNED
IPTELSDSSE THDEGEVQAF YEDLNGRQYV NEVFNFSVDK LYDLLFTDSQ FQRDFMEQRR
FSDIIFHPWK KEENGNQTRV ILYTITLTNP LAPKTATVTE TQTMYKASQE SECYVIDAEV
LTHDVPYHDY FYTINRYTLT RVARNKSRLR VSTELRYRKQ PWGLVKSFIE KNFWSGLEDY
FRHLESELTK TESTYLAEVH RQSPKEKVSK QSTVRRRKRA HTHLRVPHLE EVLSPVTTPT
DEEVAHRIKH VAGSTQTRHI PEESPSGFHL QSVSKLLLVI SFVLVLLVIL NMMLFYKLWM
LEYTTQTLTA WQGLRLQERL PQSQTEWAQL LESQQKYHDS ELQKWREIIK SSVMLLDQMK
DSLINLQNGI GSRDFGSDPE EKRKRFH
//
