ID A0A226NEE2_CALSU Unreviewed; 637 AA.
AC A0A226NEE2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 08-NOV-2023, entry version 20.
DE RecName: Full=Ras-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASZ78_008607 {ECO:0000313|EMBL:OXB65913.1};
OS Callipepla squamata (Scaled quail).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Odontophoridae;
OC Callipepla.
OX NCBI_TaxID=9009 {ECO:0000313|EMBL:OXB65913.1, ECO:0000313|Proteomes:UP000198323};
RN [1] {ECO:0000313|EMBL:OXB65913.1, ECO:0000313|Proteomes:UP000198323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texas {ECO:0000313|EMBL:OXB65913.1,
RC ECO:0000313|Proteomes:UP000198323};
RC TISSUE=Leg muscle {ECO:0000313|EMBL:OXB65913.1};
RA Oldeschulte D.L., Halley Y.A., Bhattarai E.K., Brashear W.A., Hill J.,
RA Metz R.P., Johnson C.D., Rollins D., Peterson M.J., Bickhart D.M.,
RA Decker J.E., Seabury C.M.;
RT "Disparate Historic Effective Population Sizes Predicted by Modern Levels
RT of Genome Diversity for the Scaled Quail (Callipepla squamata) and the
RT Northern Bobwhite (Colinus virginianus): Inferences from First and Second
RT Generation Draft Genome Assemblies for Sympatric New World Quail.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXB65913.1}.
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DR EMBL; MCFN01000078; OXB65913.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226NEE2; -.
DR STRING; 9009.A0A226NEE2; -.
DR Proteomes; UP000198323; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd04054; C2A_Rasal1_RasA4; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR PANTHER; PTHR10194:SF3; RASGAP-ACTIVATING-LIKE PROTEIN 1; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00616; RasGAP; 2.
DR SMART; SM00239; C2; 2.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000198323}.
FT DOMAIN 1..115
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 266..461
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
SQ SEQUENCE 637 AA; 70686 MW; 12C4D381ED9E73F9 CRC64;
MSPQPPQFAA MAKSTSLHCR LVEGKELPAK DVSGSSDPYC VVKVDNEVVA RTATVWRSLN
PFWGEEFTLR LPSSFHSLTI YVLDEDTIGH DDVIGKVSLS RQQISAQPRG IDSWLSLAPV
HPDQEVQGEI HLEVQVIKKT RFPHWNEVLE FELAEDEPGD SVLSVEVWDW DIVGKNDFLG
QVKVPLDASR PIEGWFQLLP FPSSTEEPRG QLGSLRLMVR LLEDRVLPQH CYQPLIQLLA
EPLRCPGQPA AGTALAVLEE VTSGDCRQDV ATKLVKVFLA QGLAVPFLDY IITRELARTM
DPNTLFRSNS LASKSVEQFL KAVGLPYLHA VLKPVVNRIF EEKKRISFKG SLSEAQVRDS
SLELLQGYLG DTVDAIVGSV DKCPLLMRVA FKQLRRRVEE RFPSPQHEEV QYFAISGFLF
LRFFAPAVLT PKLFGLREQH AEPRTGRTLL LLAKALQSIG NLGLQPGKES WMAPLHTVLL
PSITRVRAFL DSLIDVDSTQ GASAGGGGTT KRSHCSQTMA TATAGEGMVS VAPFGPLAII
KEGFLHAREA KEHSLLPRFA FKKRYFWLST QALSYSKSPE CQERSCIPVG HIRAVERVDE
GTFPQPHVMQ VVAQDGTGQL HTTYIQCKVG TSPSQHH
//
