ID A0A226NFV1_CALSU Unreviewed; 866 AA.
AC A0A226NFV1;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Dimethylglycine dehydrogenase, mitochondrial {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASZ78_004266 {ECO:0000313|EMBL:OXB66317.1};
OS Callipepla squamata (Scaled quail).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Odontophoridae;
OC Callipepla.
OX NCBI_TaxID=9009 {ECO:0000313|EMBL:OXB66317.1, ECO:0000313|Proteomes:UP000198323};
RN [1] {ECO:0000313|EMBL:OXB66317.1, ECO:0000313|Proteomes:UP000198323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texas {ECO:0000313|EMBL:OXB66317.1,
RC ECO:0000313|Proteomes:UP000198323};
RC TISSUE=Leg muscle {ECO:0000313|EMBL:OXB66317.1};
RA Oldeschulte D.L., Halley Y.A., Bhattarai E.K., Brashear W.A., Hill J.,
RA Metz R.P., Johnson C.D., Rollins D., Peterson M.J., Bickhart D.M.,
RA Decker J.E., Seabury C.M.;
RT "Disparate Historic Effective Population Sizes Predicted by Modern Levels
RT of Genome Diversity for the Scaled Quail (Callipepla squamata) and the
RT Northern Bobwhite (Colinus virginianus): Inferences from First and Second
RT Generation Draft Genome Assemblies for Sympatric New World Quail.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXB66317.1}.
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DR EMBL; MCFN01000066; OXB66317.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226NFV1; -.
DR STRING; 9009.A0A226NFV1; -.
DR Proteomes; UP000198323; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000198323}.
FT DOMAIN 51..414
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 417..469
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 479..744
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 770..848
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
FT REGION 15..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 866 AA; 96345 MW; 1EC0DC0897103DF8 CRC64;
MSAVLRAALR RLPLPRRGGS AGPSAASRAL AAGARGGKEE QSPSLGKDRA DTVIIGGGCV
GVSLAYHLAK AGLRDVLLLE KSELTAGSTW HAAGLTTYFH PGINLKKIHA YSIKLYEKLE
EETGQAVGFH QPGSIRIAST PTRVDEFKYQ MTRAGWHPTE QYLIPPEKVQ ELFPLLNMDK
VLAGLYNPGD GHIDPYSLTM ALAAGARKYG AQLNYPVQVT NLNPRSDGTW EVETPLGVIQ
AKRIVNTAGF WAREIGKMIG LQHPVIPVHH QYVVTSTVPE VKSLKTELPV IRDLEGSFYL
RQERDGLLFG PYESQEKMKL QDSWVTNGVP PGFGKELFES DLDRIMEYVE AAMEMVPVLK
QANIINTISG PITYTPDILP MVGPHQGVRN YWVAIGFGYG IIHAGGIGKY LSDWILEGEP
PFDLIELDPN RYGKWTTTEY TAAKARESYG FNNIIIYPKE ERFAGRPTER ISGLYNLLKT
KCSMGFHAGW EQPHWFYKPG DETGYKPSFR RTNWFDPVGR EYKQVMEKVG VIDLSPFGKF
KVKGTDSVKL LDHLFANVVP KVGSTNISHM LTPRGKVYAE LTVSQLYPGE FMLVTGSGSE
LHDLRWIEEE VVRGGYKVEI ENMTDDMGVL GVAGPYARQV LQKLTTEDLS DGSFKFLQSR
HLKLSNIAVT AVRISYTGEL GWELYHRKED SVALYNAVMD AGQKEGIDNF GTYALNALRL
EKGFRAWGAE MNCDTNPLEA GLEYFVKLNK PADFTGKKTL KQIKEKGLKR RLVYLTLETD
DVDPEGNESV WHNGKVIGNT TSGSFSYSAQ QSLAFAYVPI ELSKVGQKLE VELLGKNYPA
TIIQEPLVLT EPTRTRLQRK GQSPKI
//
