ID A0A226NI09_CALSU Unreviewed; 2471 AA.
AC A0A226NI09;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};
GN ORFNames=ASZ78_005695 {ECO:0000313|EMBL:OXB67122.1};
OS Callipepla squamata (Scaled quail).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Odontophoridae;
OC Callipepla.
OX NCBI_TaxID=9009 {ECO:0000313|EMBL:OXB67122.1, ECO:0000313|Proteomes:UP000198323};
RN [1] {ECO:0000313|EMBL:OXB67122.1, ECO:0000313|Proteomes:UP000198323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texas {ECO:0000313|EMBL:OXB67122.1,
RC ECO:0000313|Proteomes:UP000198323};
RC TISSUE=Leg muscle {ECO:0000313|EMBL:OXB67122.1};
RA Oldeschulte D.L., Halley Y.A., Bhattarai E.K., Brashear W.A., Hill J.,
RA Metz R.P., Johnson C.D., Rollins D., Peterson M.J., Bickhart D.M.,
RA Decker J.E., Seabury C.M.;
RT "Disparate Historic Effective Population Sizes Predicted by Modern Levels
RT of Genome Diversity for the Scaled Quail (Callipepla squamata) and the
RT Northern Bobwhite (Colinus virginianus): Inferences from First and Second
RT Generation Draft Genome Assemblies for Sympatric New World Quail.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in the organization of the endoplasmic reticulum
CC exit sites (ERES), also known as transitional endoplasmic reticulum
CC (tER). Required for secretory cargo traffic from the endoplasmic
CC reticulum to the Golgi apparatus. {ECO:0000256|RuleBase:RU364101}.
CC -!- SUBUNIT: SEC16A and SEC16B are each present in multiple copies in a
CC heteromeric complex. {ECO:0000256|RuleBase:RU364101}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004406}. Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU364101}.
CC -!- SIMILARITY: Belongs to the SEC16 family.
CC {ECO:0000256|ARBA:ARBA00005927, ECO:0000256|RuleBase:RU364101}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXB67122.1}.
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DR EMBL; MCFN01000044; OXB67122.1; -; Genomic_DNA.
DR STRING; 9009.A0A226NI09; -.
DR Proteomes; UP000198323; Unassembled WGS sequence.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IEA:UniProt.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:InterPro.
DR GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd09233; ACE1-Sec16-like; 1.
DR Gene3D; 1.25.40.1030; -; 1.
DR InterPro; IPR024298; ACE1_Sec16_Sec31.
DR InterPro; IPR024880; Sec16.
DR InterPro; IPR024340; Sec16_CCD.
DR PANTHER; PTHR13402:SF13; PROTEIN TRANSPORT PROTEIN SEC16A; 1.
DR PANTHER; PTHR13402; RGPR-RELATED; 1.
DR Pfam; PF12932; Sec16; 1.
DR Pfam; PF12931; Sec16_C; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|RuleBase:RU364101};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|RuleBase:RU364101};
KW Golgi apparatus {ECO:0000256|RuleBase:RU364101};
KW Membrane {ECO:0000256|RuleBase:RU364101};
KW Protein transport {ECO:0000256|RuleBase:RU364101};
KW Reference proteome {ECO:0000313|Proteomes:UP000198323};
KW Transport {ECO:0000256|RuleBase:RU364101}.
FT DOMAIN 1520..1617
FT /note="Sec16 central conserved"
FT /evidence="ECO:0000259|Pfam:PF12932"
FT DOMAIN 1689..1923
FT /note="Ancestral coatomer element 1 Sec16/Sec31"
FT /evidence="ECO:0000259|Pfam:PF12931"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 35..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 89..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 598..638
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 669..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 883..910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1111..1248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1279..1308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1392..1446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1961..1981
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2061..2413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2451..2471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..621
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..823
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 833..850
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1178..1207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1231..1246
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1392..1425
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1427..1446
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2105..2119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2138..2163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2174..2188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2202..2235
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2236..2259
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2331..2347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2372..2393
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2471 AA; 268017 MW; 7C2971B6A9AD8B07 CRC64;
MQQPPQPAPA GAAAPPPAGI ARNMYWRNTS LSKRANATAA PVQPVTDPFA FGRQTSQGSP
LDNPSKGNAL VMQGSSPAVF PQPAVLHASL SHAGDNPHGL HPSSSAPVPQ PGLNSSVFPN
VPVPAPSPGC VTSSTTEMHP NADLGLHGSA VPSHYNAGTA LESSFSVHPG MVSMSNSPGV
RQDANRDPSD VPSGPTAAAA LFPPPPQQPV SQWRPVQGNL QAPVRNFVPY PEPPSQTDIH
NVSQSSVSTS HPPAQTNVQR GPGHQGIPQN ALQAPLSVGS EKDGKNGSAN SGHQMNSIQP
GNVFRQNAEM ANAWLNQPYQ EQFYPQPPLQ DSSSVIPTAQ ESHLKQQSPG MSETSNRPIR
TDQDSGTLSM FFKGDEAENE EILSSEKNYV VEKTEFACQP HSSPLYHQPV HPQRVPANVL
SQAQVGTGLA NEMVQKGMDV QYFPRILTQQ EAQAAKQSMF VTDDRVGTGD APGNGGSQYE
NVENLECIQN QEVLPSEPRN MNASSPSAHP DLYRYGSLPG QMLPKNAVVS HAEGGPNLEA
PDSLAHPVRP DSVSSNYSNI SHRSASSSAR PQEQIGTFIQ QESGKPDEES SARFFKQIDS
SPLGDDSSEI NPNKNYHGNL SQPPTPSPPK PTGVFQTSAN SSFEPVRSHG VGIKPAEIDQ
AKMVVELRES HPNQRNAKRS TAVPAASPGN LEQPPDNLET IFMPQVYPLP LAVTGEAGSM
LHSGPVTDNM QSLPERRSST RAQGAIKKCD SPATTLWAHN ELPNFGGNVL LAPAAPAVYV
PAKQTVEVIQ PPEEGLSNQQ PNKPGSIAVQ PSQDGNISSE NLENPPKMGE EEALQSQASS
GYASLLSSPP TESLQNQPIL IAQPNQSYNL AQPINFSISL SNQLSSNENS QPMKDSGVGD
KPSIGPQTLH AGGIISGENA LLPVMQVGSL LANAPPNSNL LKHNLLQSPV NSSDVASNQP
ANLLMKTPSN LALEGQKNVN FEGFVPEFAS KSGANSSISP GMNLPSGSTS ALLPPVNSVV
QTKNSVNRSN SKEEAAGVLD FTVSRTLEKG SASNSVQVHN QVLSDGPVYP QQPVGSAGQV
GPEVRDNQHF YQQVTKDVQH QAVPDRAVQG ALPSQPQMQA AQMPAASGQS SASSNYHTAA
GTQGTQATQQ SENQELRNQE ASSAQLPSPD KQPGPGQPSG AQAPTAPTTS SQPVQPSTQQ
DLQRPPLPQT PQDAFGPPQN PYYYYRHPYD AYQPPYPPPY PPPDPRTAAH LYYLEDNYGQ
YDPRYRYYDS SSTAYMEPGS YRYSEPERPS SRASHCSDRP SSRQGYPEDY YAKTGWTDYY
PGYYPNAYDY GDPSRWERYP SAYDPRYRDP RSFDQRYLYD GEHSPYQKRE AYPYSNRHDR
YEDRWRYDPR FTGSFDDETE PHRDPYGDEF DRRSVHSEHS GHSLRSSHSV HSRQSSFSSR
SQQSQLYRSN HDLTASAYET AAQAVSLHTD YPYGGYAPNY DGQQPFTDYG YPTEAGWSAV
EQAPLRPSTP EKFSVPHLCA RFGPGGFLIK VLPNLPSEGQ PALVEVHSME TMLQHSPEQE
EMRAFPGPLA KDDTHKVDVI NFAQNKATQC FKNENLIDKE SASLLWDFIV LLCRQNGTVV
GTDLAELLLR DHKTVWLPGK SPNEANLIDF NNEALEQVEE ESGEAQLSFL TDSLITTIDS
LEKETERFRE LLLYGRKKDA LESAMKHGLW GHALLLASKM DNRTHARVMT RFANSLPIND
PLQTVYQLMS GRMPAASTCC GDEKWGDWRP HLAMVLSNLT NNVDLESRTI ATMGDTLASK
GLLDAAHFCY LMAQVGFGVY TRKTTKLVLI GSNHSLPFLK FATNEAIQRT EAYEYAQSLG
TQPGCLPNFQ VFKFIYACRL AEMGLAAQAF HYCEVISRTV LKDPHYYSPV LIGQLIQMSS
QLRLFDPQIK EKPDQESFVE PSWLVRLRHV DVQIKDGTIA YNTDRSTPQQ YPCSTPSSEL
DHNSQYDGAG VGHDMGPGAE NALLASLLPS MSQQMQSVQL MPSAPQAILD GSAAGIPPSD
QEAVQSVPFY PVASQPVGPA PGFAPPGFSN QYGAEPSPLY LGSTLPPGGP PQEAEPREEE
QTNLETGMQR MASESPSRNS FPEQREEDFY SRMARMGYGQ RSRTTSESSA HSVGRERSNS
AAKQPSPPPV PAVKETKKDV KKEPASRKSG ANWFRWLMGK GKNEAHLPDD KNKSIVWDEQ
KQRWVNLDEP EEESKPPPPP PTGFPKVPQT APSGPGGPPS APVNMFSRRA AGSRARYVDV
LNPGGTKSSG AVPAPSDLFA PLAPMPIPAN VFVPNAVPGD PQPTEGSGAA EHTPAANQTN
TDPSAAVDQE YLNPAILPPG SGLPVSNPDG FQPGELSRSS SMSSLSREVS QHFNQPAPVP
VPPSGDPSAG AVQFYNPSQF AQDENLADSF CVLSPWHYFT DGFCSSFFQS PAVTGSSRPG
RIGQRKYPTL K
//
