ID A0A226NN48_CALSU Unreviewed; 848 AA.
AC A0A226NN48;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
DE Flags: Fragment;
GN ORFNames=ASZ78_002253 {ECO:0000313|EMBL:OXB68838.1};
OS Callipepla squamata (Scaled quail).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Odontophoridae;
OC Callipepla.
OX NCBI_TaxID=9009 {ECO:0000313|EMBL:OXB68838.1, ECO:0000313|Proteomes:UP000198323};
RN [1] {ECO:0000313|EMBL:OXB68838.1, ECO:0000313|Proteomes:UP000198323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texas {ECO:0000313|EMBL:OXB68838.1,
RC ECO:0000313|Proteomes:UP000198323};
RC TISSUE=Leg muscle {ECO:0000313|EMBL:OXB68838.1};
RA Oldeschulte D.L., Halley Y.A., Bhattarai E.K., Brashear W.A., Hill J.,
RA Metz R.P., Johnson C.D., Rollins D., Peterson M.J., Bickhart D.M.,
RA Decker J.E., Seabury C.M.;
RT "Disparate Historic Effective Population Sizes Predicted by Modern Levels
RT of Genome Diversity for the Scaled Quail (Callipepla squamata) and the
RT Northern Bobwhite (Colinus virginianus): Inferences from First and Second
RT Generation Draft Genome Assemblies for Sympatric New World Quail.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXB68838.1}.
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DR EMBL; MCFN01000008; OXB68838.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A226NN48; -.
DR STRING; 9009.A0A226NN48; -.
DR Proteomes; UP000198323; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:InterPro.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR GO; GO:0051171; P:regulation of nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0080090; P:regulation of primary metabolic process; IEA:UniProt.
DR CDD; cd09769; Luminal_IRE1; 1.
DR CDD; cd10422; RNase_Ire1; 1.
DR CDD; cd13982; STKc_IRE1; 1.
DR Gene3D; 1.20.1440.180; KEN domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR045133; IRE1/2-like.
DR InterPro; IPR010513; KEN_dom.
DR InterPro; IPR038357; KEN_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR13954; IRE1-RELATED; 1.
DR PANTHER; PTHR13954:SF15; SERINE_THREONINE-PROTEIN KINASE_ENDORIBONUCLEASE IRE2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF06479; Ribonuc_2-5A; 1.
DR SMART; SM00564; PQQ; 3.
DR SMART; SM00580; PUG; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS51392; KEN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198323};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 428..689
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 692..841
FT /note="KEN"
FT /evidence="ECO:0000259|PROSITE:PS51392"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OXB68838.1"
SQ SEQUENCE 848 AA; 94424 MW; 19198E4D858DD668 CRC64;
PILQVPVYVA EPAFLPDPND GSLYILGGKK KEGLMKLPFT IPELVQSSPC RSSDGVLYTG
KKQDMWFIVD PKSGEKQTTL STEAWDGVCP SSPLLYIGRT QYVITMYDTK TRELRWNATY
SDYSAPLYEE SYPYKMSHFA SSGDGLVVTL DKESGEVLWA QNYGSPVVGI YVWHQDSLRR
VPHLNLAMET LRYLTFHSQD IHLARWGHQS MKDFTATKTQ LLPALYVGKH AASFYALTSL
VHGSVALVPQ GITLARIDGP TTDDVTMRES GECEITPSTD VKYPQGSITA LRNQWLLIGH
HELPPVVHTT MLRAFPENLR KATETIIPRS SPARTVFDDF LAPSSTEELA LRGSEGHVPP
EARHREQAEV YPDSGDWDLL LAAVGTALLG GGVLMLLVMV RGLLLASGSL HSSAEVEPEV
VVVGKVSFNP KDVLGHGAGG TFVFRGQFEG RNVAVKRLLP ECFHLVDREV RLLQESDEHP
HVVRYFCTEK DRQFHYIAIE LCSATLQEYV ESPSFDRRSL DPVSVLHQTM SGLAHLHSLS
IVHRDLKPCN ILISVPNSHG HIRAVISDFG LCKKLQGGRH SFSLRSGIPG TEGWIAPELL
QEAPKENPTC AVDIFSAGCI FYYVVSGGQH PFGDSLRRQA NILAGACQLP CLQEDVHDSV
VARELIVSML SSEPQKRPSA PAVLMHPFFW SAEKQLQFFQ DVSDRVEKEP AEGSLVGALE
AGGRSVVRTN WRMHISLPLQ MDLRKFRTYK GGSVRDLLRA MRNKVHPTHP LPHTALPSLT
PFLPQKHHYH ELPADVREAL GSVPDGFMQY FTSRFPRLLL HTHSAMQLCA HERLFHPYYG
PELQGTGR
//
