GenomeNet

Database: UniProt
Entry: A0A226PIM2_COLVI
LinkDB: A0A226PIM2_COLVI
Original site: A0A226PIM2_COLVI 
ID   A0A226PIM2_COLVI        Unreviewed;       328 AA.
AC   A0A226PIM2;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   11-DEC-2019, entry version 11.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OXB79518.1};
GN   ORFNames=H355_000334 {ECO:0000313|EMBL:OXB79518.1};
OS   Colinus virginianus (Northern bobwhite) (Tetrao virginianus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Odontophoridae;
OC   Colinus.
OX   NCBI_TaxID=9014 {ECO:0000313|EMBL:OXB79518.1, ECO:0000313|Proteomes:UP000198419};
RN   [1] {ECO:0000313|EMBL:OXB79518.1, ECO:0000313|Proteomes:UP000198419}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texas {ECO:0000313|EMBL:OXB79518.1,
RC   ECO:0000313|Proteomes:UP000198419};
RX   PubMed=24621616;
RA   Halley Y.A., Dowd S.E., Decker J.E., Seabury P.M., Bhattarai E.,
RA   Johnson C.D., Rollins D., Tizard I.R., Brightsmith D.J., Peterson M.J.,
RA   Taylor J.F., Seabury C.M.;
RT   "A Draft De Novo Genome Assembly for the Northern Bobwhite (Colinus
RT   virginianus) Reveals Evidence for a Rapid Decline in Effective Population
RT   Size Beginning in the Late Pleistocene.";
RL   PLoS ONE 9:E90240-E90240(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822}; Multi-
CC       pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXB79518.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AWGT02000067; OXB79518.1; -; Genomic_DNA.
DR   Proteomes; UP000198419; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003275; K_chnl_inward-rec_Kir3.2.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF19; PTHR11767:SF19; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01328; KIR32CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU003822, ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822, ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198419};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822, ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM        87..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        161..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          51..190
FT                   /note="IRK"
FT                   /evidence="ECO:0000259|Pfam:PF01007"
FT   DOMAIN          197..312
FT                   /note="IRK_C"
FT                   /evidence="ECO:0000259|Pfam:PF17655"
FT   SITE            176
FT                   /note="Role in the control of polyamine-mediated channel
FT                   gating and in the blocking by intracellular magnesium"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR005465-1"
SQ   SEQUENCE   328 AA;  37642 MW;  8FF51D4ED600EA7C CRC64;
     MAANVLEEDS MEQDIESPVT IHQPKLPKQA REDLPKNLNK ECAKRKIQRY VRKDGKCNVH
     HGNVRETYRY LTDIFTTLVD LKWRFNLLIF VMVYTVTWLF FGMIWWLIAY MRGDMDHIGD
     STWTPCVSNL NGFVSAFLFS IETETTIGYG YRVITDKCPE GIVLLLIQSV LGSIVNAFMV
     GCMFVKISQP KKRAETLVFS TNAVISMRDG KLCLMFRVGD LRNSHIVEAS IRAKLIKSKQ
     TKEGEFIPLN QTDINVGYYT GDDRLFLVSP LIISHEINQQ SPFWEISKAQ LPKEELEIVV
     ILEGMVEATV HMRWITSAED ATRPTVYN
//
DBGET integrated database retrieval system