ID A0A227PIN2_9FLAO Unreviewed; 604 AA.
AC A0A227PIN2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN ORFNames=B0A64_02930 {ECO:0000313|EMBL:OXG08966.1};
OS Flavobacterium araucananum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=946678 {ECO:0000313|EMBL:OXG08966.1, ECO:0000313|Proteomes:UP000214684};
RN [1] {ECO:0000313|EMBL:OXG08966.1, ECO:0000313|Proteomes:UP000214684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24704 {ECO:0000313|EMBL:OXG08966.1,
RC ECO:0000313|Proteomes:UP000214684};
RA Stine C., Li C., Tadesse D.;
RT "Whole genomes of Flavobacteriaceae.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXG08966.1}.
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DR EMBL; MUGS01000004; OXG08966.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A227PIN2; -.
DR OrthoDB; 9801077at2; -.
DR Proteomes; UP000214684; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..604
FT /note="Beta-glucuronidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030039569"
FT DOMAIN 77..205
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 212..301
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 304..535
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 604 AA; 69589 MW; 6C9769860CC95DCB CRC64;
MKKRITLLLL MAVCIGQAQS LISNVPNRNT TSLNGVWNYI VDPYETGYYS FHHDEYDKQE
KPSNAAYFNN YHAVNKQELV EYDFDKSPKI NIPGDWTSQV PELKYYEGNV WFKKSFDYNL
AATKRLFLYL GAINYKADVY LNGKKLGRHE GGFTPFNYEV TSIVKPKDNY LVIKVDNTRH
KEDVPTINTD WWNYGGITRD VTLIEENESF VEDYNIQLKK GNAALISGFV KINTFNPAQN
DVTISIPELK INYKGKIGAD GLVNFEIPAK KISYWSPENP KLYEVTIDFN GVKLKDNIGF
RTIETQEDKI LLNGKPIFLR GISIHEENAK GGRANSEEDA LRLLNWAKEL GCNYVRLAHY
PHNENIVRTA DKLGLMVWEE IPVYWTVEFT NKATYQNAQD QLTAAVTRDK NRACIIIWSM
ANETPISDSR NAFIKNLVDH TKSLDNTRLI SAALLTQSGA DGFGTINDEI GQYLDIISFN
QYLGWYGGKL EDAEKIFWKT KYNKPVIVSE FGGDAKQGLH GEKNERWTEE FQEYLYIQNL
KMIEKIPHLS GLSPWILVDF RSPRRLLPGI QDEYNRKGLI SNDGNKKKAF YIMQDWYAKK
KKEY
//
