ID   A0A229SUJ2_9PSEU        Unreviewed;       569 AA.
AC   A0A229SUJ2;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=2,3-dihydroxybenzoate-AMP ligase {ECO:0000313|EMBL:OXM62636.1};
GN   ORFNames=CF165_33130 {ECO:0000313|EMBL:OXM62636.1};
OS   Amycolatopsis vastitatis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=1905142 {ECO:0000313|EMBL:OXM62636.1, ECO:0000313|Proteomes:UP000215199};
RN   [1] {ECO:0000313|Proteomes:UP000215199}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H5 {ECO:0000313|Proteomes:UP000215199};
RA   Adamek M., Alanjary M., Sales-Ortells H., Goodfellow M., Bull A.T.,
RA   Kalinowski J., Ziemert N.;
RT   "Comparative genome mining reveals phylogenetic distribution patterns of
RT   secondary metabolites in Amycolatopsis.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXM62636.1}.
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DR   EMBL; NMUL01000039; OXM62636.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A229SUJ2; -.
DR   OrthoDB; 9803968at2; -.
DR   Proteomes; UP000215199; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   CDD; cd04433; AFD_class_I; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:OXM62636.1}.
FT   DOMAIN          43..428
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          483..558
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   569 AA;  61421 MW;  959BF56D078D969B CRC64;
     MRCHREGRAR DFRARGWWSA ETIDQLVKER VSADPEGLAL VDPPNTTALV GRDPVRWTWN
     RLDERVDVLA AFLLARGVRA GDVVAVQLPN CSALVQAFLA IVRIGAIVTP FPVSYREHEL
     GPMCRRTGSA GVVTASRYGE HELAGAALGL GASAPSVRFV VARGDDEPAG ALAWPEDPLS
     EAGKSALDEY LSALETDVDD CVTICWTSGT EAEPKAVPRC HGDWLATAAG CVQAAGMTRD
     DVLLSPFPMT NMAGIGGMFL PWLLTGAVFV PHHPFDLPVF LGQLAAERVT YTLAPPALLT
     MLLRNETVLS QKVLSGVDIS ALRKIGSGSA PLSPWLVRTW AQRYGIDIIN FFGSNEGTAL
     LSGPVDIPDP DQRASYFPNY ASAVTWSTPV AGWTSVRLHD PVTGERVTEP GHPGELHIAG
     PTVFAGYLRE MGEPLDTSAF DDDGHFRTGD VFEIAGERGE FLRYVDRMKD LVIRGGMNIS
     PAEVEGLLAG HPDVADVGVV GVPDDVMGER VCAVVVPGAR KPTLEELVAY LRERKVAAFK
     LPERLEYADA LPRNPVGKIL KRQLRESLG
//