ID A0A229XKT0_9EURO Unreviewed; 578 AA.
AC A0A229XKT0;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=Pre-mRNA-processing protein 45 {ECO:0000256|ARBA:ARBA00022160, ECO:0000256|RuleBase:RU367140};
GN Name=PRP45 {ECO:0000313|EMBL:RHZ69599.1};
GN ORFNames=CDV55_107793 {ECO:0000313|EMBL:RHZ69599.1}, CFD26_108122
GN {ECO:0000313|EMBL:RLL99334.1};
OS Aspergillus turcosus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1245748 {ECO:0000313|EMBL:RHZ69599.1, ECO:0000313|Proteomes:UP000215394};
RN [1] {ECO:0000313|Proteomes:UP000215289, ECO:0000313|Proteomes:UP000215394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMR AF 1038 {ECO:0000313|EMBL:RLL99334.1}, and HMR AF 23
RC {ECO:0000313|EMBL:RHZ69599.1};
RA Parent-Michaud M., Dufresne P.J., Fournier E., Martineau C., Moreira S.,
RA Perkins V., De Repentigny L., Dufresne S.F.;
RT "Draft genome sequences of two Aspergillus turcosus clinical strains
RT isolated from bronchoalveolar lavage fluid: one azole-susceptible and the
RT other azole-resistant.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in pre-mRNA splicing.
CC {ECO:0000256|RuleBase:RU367140}.
CC -!- SUBUNIT: Associated with the spliceosome.
CC {ECO:0000256|RuleBase:RU367140}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU367140}.
CC -!- SIMILARITY: Belongs to the SNW family. {ECO:0000256|ARBA:ARBA00010197,
CC ECO:0000256|RuleBase:RU367140}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHZ69599.1}.
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DR EMBL; NKHV02000036; RHZ69599.1; -; Genomic_DNA.
DR EMBL; NIDN02000034; RLL99334.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A229XKT0; -.
DR STRING; 1245748.A0A229XKT0; -.
DR OrthoDB; 5490078at2759; -.
DR Proteomes; UP000215289; Unassembled WGS sequence.
DR Proteomes; UP000215394; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-UniRule.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR InterPro; IPR017862; SKI-int_prot_SKIP.
DR InterPro; IPR004015; SKI-int_prot_SKIP_SNW-dom.
DR PANTHER; PTHR12096; NUCLEAR PROTEIN SKIP-RELATED; 1.
DR PANTHER; PTHR12096:SF0; SNW DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02731; SKIP_SNW; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|RuleBase:RU367140};
KW mRNA splicing {ECO:0000256|RuleBase:RU367140};
KW Nucleus {ECO:0000256|RuleBase:RU367140};
KW Reference proteome {ECO:0000313|Proteomes:UP000215289};
KW Spliceosome {ECO:0000256|RuleBase:RU367140}.
FT DOMAIN 191..349
FT /note="SKI-interacting protein SKIP SNW"
FT /evidence="ECO:0000259|Pfam:PF02731"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..413
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..534
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..578
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 578 AA; 65047 MW; DA86600FDB071AEC CRC64;
MTSIAEGLFK SLPKPKYTGE DEEVPQHAQP RGPRIVGADQ IDQSQIVLRK TGPPPYGNRT
GWRPRAPEDF GDGGAFPEIL VAQYPLDMGR KGTASTSNAL AVQVDAEGKV KYDAIARRGH
SENRIVHASF KDLIPLRQRV DMGEISLDRP SEEEVEAQME KTKNALASLV QGAVAAQKPK
NVKGGRRAEP TFVRYTPANQ MGDTTRKNDR IMKIVERQQD PMEPPKFKHK KIPRGPPSPP
PPIMHSPPRK LTAEDQEAWR IPPPVSNWKN PKGYTVPLDK RLAADGRGLQ DVTINDKFAQ
FAEALFTADR HAREEVRLRA QMQQKLAEKE KAQKEEHLRA LAQKAREERA ASSRRDSRAR
SRTRSVSRSP SAYSRSATPS DDEEAARERE RIRRERRQDA ERQLRQSRMG TERRIQMMAR
EQNRDISEKV ALGLAKPTQT SESMWDSRLF NQTSGMHAGF NEDNPYDKPL FAAQDAINSI
YRPRAQLDVD DEEGAEGEMS KIQKTNRFEV LGKAKEGFRG AAEAETRDGP VQFEKDTTDP
FGIDSMIADV TGGAGQKRYG IQEVEREDGR SKRARTDD
//
