ID   A0A231MZX5_9GAMM        Unreviewed;       866 AA.
AC   A0A231MZX5;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=Adenylate cyclase {ECO:0000256|ARBA:ARBA00021420};
DE            EC=4.6.1.1 {ECO:0000256|ARBA:ARBA00012201};
DE   AltName: Full=ATP pyrophosphate-lyase {ECO:0000256|ARBA:ARBA00032597};
DE   AltName: Full=Adenylyl cyclase {ECO:0000256|ARBA:ARBA00032637};
GN   ORFNames=CGX12_08450 {ECO:0000313|EMBL:OXS15590.1};
OS   Zobellella denitrificans.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Zobellella.
OX   NCBI_TaxID=347534 {ECO:0000313|EMBL:OXS15590.1, ECO:0000313|Proteomes:UP000215233};
RN   [1] {ECO:0000313|EMBL:OXS15590.1, ECO:0000313|Proteomes:UP000215233}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ZD1 {ECO:0000313|EMBL:OXS15590.1,
RC   ECO:0000313|Proteomes:UP000215233};
RA   Wu Y.-W., Chu K.-H.;
RT   "Draft genome of Zobellella denitrificans ZD1.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP = 3',5'-cyclic AMP + diphosphate; Xref=Rhea:RHEA:15389,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:58165; EC=4.6.1.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001593};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-1 family.
CC       {ECO:0000256|ARBA:ARBA00007901, ECO:0000256|RuleBase:RU004184}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXS15590.1}.
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DR   EMBL; NMUO01000029; OXS15590.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A231MZX5; -.
DR   OrthoDB; 5571448at2; -.
DR   Proteomes; UP000215233; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000274; Adenylate_cyclase_1.
DR   InterPro; IPR024686; Adenylate_cyclase_1_CS.
DR   InterPro; IPR024685; Adenylate_cyclase_1_N.
DR   PANTHER; PTHR38760; ADENYLATE CYCLASE; 1.
DR   PANTHER; PTHR38760:SF1; ADENYLATE CYCLASE; 1.
DR   Pfam; PF12633; Adenyl_cycl_N; 1.
DR   Pfam; PF01295; Adenylate_cycl; 1.
DR   PIRSF; PIRSF001444; Adenylate_cycl; 1.
DR   PROSITE; PS01092; ADENYLATE_CYCLASE_1_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   cAMP biosynthesis {ECO:0000256|ARBA:ARBA00022998};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          37..231
FT                   /note="Adenylate cyclase class-I N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12633"
SQ   SEQUENCE   866 AA;  98975 MW;  56EA1DE794387445 CRC64;
     MADIVHLLAN CYHDHTFDLS RVCVGPTKAC TLHANFHRLV ERCDQFNQQK QARALAVMSR
     YGQQVFQLLP VLLHYHHPLL PGYLPGDVPA GVCHFRPNER QQEFIDELCQ AANGHQGLQH
     GKNEIFGLYS MGSTSSIGQC RHSDLDVWVC YSHQMAPERV ELLQQKCLLI SKWAEQRQVE
     LNLFLIPDNK FRTDNQQWVQ GESCGSAQHL LLLDEFYRSN LRIAGKRLVW MFAPGKLGPK
     YDQFVAEQFA NGTLNTDEWL DLGGFARIPA EEYFGSALWQ LYKGIDSPYK AVLKTVLMEA
     YSHEYPDTQL LCRHLKGHFQ SSEVLDEYQD HYMLMLEKVT GYLKSIGDEK RLDLVRRCFY
     LKVSEGLHRT HGNDAQYAWR RKLINRLVAA WGWPADKLAR LDDRAHWKVE EVKAAYGELL
     EALMQSYRNL IQFARRNNIS ECINPEDIGI LSRKLYAAFE NLPGKVQLIN LKIAPDLSEP
     DISLVQVPEG RVNPAGWYLY KCGLAPGDII GRSPLEYSGY VGKLVAWAHF NGLLVPSTRL
     HLFNQNTDLT RRHLQEFCGD LARIFPVRTP APTNLALSRP CEVRNLGIFL NLETDPTARW
     RNRAIEFSAK TSDPFSFGHQ LENLVGSVDL IYRNSWDEIR TLHFSGPTAV VEALTTILGK
     MHQDANAPES LDVHCYSLNF RSLIRTRFEQ LVKECIGLRL ARAQGSTIKT LVLGGDKYGI
     FFERRGVSVQ KMENAVDFYR QLSSQKQSRH ALRLDQQDDK AVPDIVDAYA SEGLMQFFFE
     DAGDGYNLYI LDEANRVEVY RQVSGSKDEL VQSINRFYTS HHEHGVGQSH FANFNLPQYY
     EIVAADGQPR VLPYRTVKDD PRACLG
//