ID   A0A231RJN0_9BACL        Unreviewed;       697 AA.
AC   A0A231RJN0;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=B1A99_13235 {ECO:0000313|EMBL:OXS58916.1};
OS   Cohnella sp. CIP 111063.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Cohnella.
OX   NCBI_TaxID=1955714 {ECO:0000313|EMBL:OXS58916.1, ECO:0000313|Proteomes:UP000215193};
RN   [1] {ECO:0000313|EMBL:OXS58916.1, ECO:0000313|Proteomes:UP000215193}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIP 111063 {ECO:0000313|EMBL:OXS58916.1,
RC   ECO:0000313|Proteomes:UP000215193};
RA   Dastager S.G., Neurgaonkar P.S., Dharne M.S.;
RT   "Cohnella sp SGD-V74 (T) CIP 111063, whole genome shotgun sequencing
RT   project.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OXS58916.1}.
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DR   EMBL; MWSG01000007; OXS58916.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A231RJN0; -.
DR   Proteomes; UP000215193; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000215193}.
FT   DOMAIN          182..536
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         203..210
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   697 AA;  79083 MW;  5F990735CF96DAA2 CRC64;
     MDTQSPVVRE EQERLQETFG EIDRQRSGIG PVYRGQDFTE QLLEEKREES RRRLDLLDKE
     PYFGRLDFKE NGKTAALPLY IGKRGMDRQD TGEPYVIDWR APVASLFYSF TGGDAPVSYD
     APDGTIQGDI YRKRNLSIRD RKLGRIVDSY ERGGDNIGLN DEFLLYKLGD KKDNKLRDIV
     STIQAEQDRI IRAPRHKALI IQGAAGSGKT TVALHRLAFL LYQYQQQIRA ERMIIFAPNT
     MFLDYISGVL PELGVGDVKQ TTFADWALDR LSGNVKLAKD ASEGELWFSL AGARPQIDDE
     TPGRYKGSLA FKALLDEQLR SLETHFLEPQ PFEPWEGRVL PAANIREWFE VEYRHYPLAP
     RLERLQARIN RWLEMQLGEI GDPKIRKDKA KTGKQRLRAY VNKLPKADAL SFYQRLFSAD
     GAADIPKSIV QSTKAYLKKG EVRHEDLPAL VWIHYAFNGA EKLSFDHVVV DEAQDVSPLQ
     IALLNAFMSE PSFTILGDLA QGIHAYRGVQ RWEELSDVFA EEYRSYHALQ QSYRSTLEII
     EFANRILPHT GTSLPPAVPV FRSGDPVEVA KLDGETDRLP RIERFIRDNR ERGMQTIAIV
     CRTDDDCARL AELLQASGIE ANLISENQTQ YRGGITVVPV YLAKGLEFDA VLVADADDRR
     YAAAPQDAKL LYVACTRALH RLTLMYLGQP SPLIAEA
//