ID A0A232EMQ4_9HYME Unreviewed; 1132 AA.
AC A0A232EMQ4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Rab-GAP TBC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TSAR_013349 {ECO:0000313|EMBL:OXU19592.1};
OS Trichomalopsis sarcophagae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Proctotrupomorpha;
OC Chalcidoidea; Pteromalidae; Pteromalinae; Trichomalopsis.
OX NCBI_TaxID=543379 {ECO:0000313|EMBL:OXU19592.1, ECO:0000313|Proteomes:UP000215335};
RN [1] {ECO:0000313|EMBL:OXU19592.1, ECO:0000313|Proteomes:UP000215335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Alberta {ECO:0000313|EMBL:OXU19592.1,
RC ECO:0000313|Proteomes:UP000215335};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXU19592.1};
RX PubMed=28648823; DOI=10.1016/j.cub.2017.05.032;
RA Martinson E.O., Mrinalini, Kelkar Y.D., Chang C.H., Werren J.H.;
RT "The Evolution of Venom by Co-option of Single-Copy Genes.";
RL Curr. Biol. 27:2007-2013(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXU19592.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NNAY01003342; OXU19592.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A232EMQ4; -.
DR STRING; 543379.A0A232EMQ4; -.
DR Proteomes; UP000215335; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd13351; PH-GRAM1_TCB1D9_TCB1D9B; 1.
DR CDD; cd13354; PH-GRAM2_TCB1D9_TCB1D9B; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR InterPro; IPR036014; TCB1D9/TCB1D9B_PH-GRAM1.
DR InterPro; IPR036017; TCB1D9/TCB1D9B_PH-GRAM2.
DR PANTHER; PTHR47666; PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47666:SF1; TBC1 DOMAIN FAMILY MEMBER 9B ISOFORM X1; 1.
DR Pfam; PF02893; GRAM; 2.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00568; GRAM; 2.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000215335}.
FT DOMAIN 487..674
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT DOMAIN 847..882
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 948..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1047..1075
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1057..1075
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1132 AA; 128450 MW; 9A16989C4F4459BD CRC64;
MLAGVLSSFF LTTSDGTFRI TEEASVYFVR QRRKGHGKTR GLTSIIVGTL DSVFDTKPPP
FRILHQTPSS EVYWMVACSL THTEIVKDWE WLHANLPSTL QSFDTEEEIT DFVCCKIQSI
IANNASDCKL VDDEDSQSFK RVSYKFHQLF NLPKEDKLVN YYSCSYWKTH LPRQGWLYLS
VNQMCFYAYI LSKETKLVIR WADIVELDKT NSLLFPDSIR IVTRDGKEHY FSMFLHKSET
YSLMEQLTNL AMKRLIDEKS GFNEDRDLLN KLSKNVPKKP SFLKRDLDAR AQSEAYRLQF
RLPGSEKLDG CVDATLWTPY DKRHNWGKIY LSQNYLCFES RVKNLVSLVI PLREVRLIES
AENQASNTAV DKSILVTTAR ASFLFAQIHD RDFVLQKISE LLAKTKIATV SLADSIVDKS
NKGREAKPVE TWTSQPPLMK LFKAPLNAEA AVKQEAKEKQ WELHFSEYGR GMTIYRTVET
AKLVITGIPQ NLRGEVWLTF SGALNEMAVN PGLYKSLVDQ SLGKTCQANE EIERDLHRSL
PEHPAFQSDI GISALRRVLS AYAYRNPQIG YCQAMNIVAS VLLIYCSEES AFWQLCNVCE
SLLPDYYDRR VVGALVDQGL LEELAQEHLP ALYVKLQELG LIRVISLSWF LTIFLSVMPT
SSAVNIMDCF FYDGAKVIFQ VALTVLEWNQ EKLLKCHDDG EAMQLLTDYL GGVYNDEGPV
LPRPIDSAPP KKSISIQTLI YESYARYGSL TIGGIERLRL KHRLRVVQSL EEGIEKNVIR
SVVSEKLMTT EELQELLNLV RGELMCQRKS EPDRYDPTQP PYEVYKIDYD LFRILFAGLS
PWGKCTQAES LSARLFRLMD RNHDNLLNFR EVVQAIAMTA TVDSSQRLKL LYTLHLPPLL
TPVDFESPTQ SDGAEVAAEA TDFFDSMEQS VASLEVPVSL AEEPCNTLSR STSMNSQQGD
QSWEEQSMGS LRSMIASRDS PLDLKNVPKM SQLHFIALWK TLYDMFPAQP EDQDTYHCIA
EIGTLLLQLG DVGKKFYVER EESEDSLAAA SSAMHPTVMS PDRNGNPATP SPSAADPNWS
ITVEQFLASA LNGEPIVNFF SKRANLLDAI ASIRDRRFKR AHSLSDPPVL HV
//
