ID A0A232ENW3_9HYME Unreviewed; 2644 AA.
AC A0A232ENW3;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|SMART:SM00181};
GN ORFNames=TSAR_011345 {ECO:0000313|EMBL:OXU20017.1};
OS Trichomalopsis sarcophagae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Proctotrupomorpha;
OC Chalcidoidea; Pteromalidae; Pteromalinae; Trichomalopsis.
OX NCBI_TaxID=543379 {ECO:0000313|EMBL:OXU20017.1, ECO:0000313|Proteomes:UP000215335};
RN [1] {ECO:0000313|EMBL:OXU20017.1, ECO:0000313|Proteomes:UP000215335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Alberta {ECO:0000313|EMBL:OXU20017.1,
RC ECO:0000313|Proteomes:UP000215335};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXU20017.1};
RX PubMed=28648823; DOI=10.1016/j.cub.2017.05.032;
RA Martinson E.O., Mrinalini, Kelkar Y.D., Chang C.H., Werren J.H.;
RT "The Evolution of Venom by Co-option of Single-Copy Genes.";
RL Curr. Biol. 27:2007-2013(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXU20017.1}.
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DR EMBL; NNAY01003075; OXU20017.1; -; Genomic_DNA.
DR STRING; 543379.A0A232ENW3; -.
DR Proteomes; UP000215335; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 7.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR PANTHER; PTHR46513:SF13; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 4-LIKE PROTEIN; 1.
DR PANTHER; PTHR46513; VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED; 1.
DR Pfam; PF14670; FXa_inhibition; 3.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00135; LY; 9.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF63825; YWTD domain; 7.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000215335};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1115..1136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 720..760
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 1469..1509
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 2244..2284
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 2597..2641
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT REGION 1145..1184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1877..1965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1145..1182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2644 AA; 296733 MW; 98B77DC0935B9723 CRC64;
MTVTRSTVVL YSVVISVIVG VCVGLGVWFL KPNDNSNYTT TESSVTTTTK DLNEPSDWPV
DARAGLIVRT DTGIRVWNYH DEKWIDFRRG FYPVVDYYKN ETLYYCTTSN YSPIRSTSRR
FPDLKYPGDD WMVNALAVDD LTKKLYVYDE TSGKIDLFDL QGKYMGIILS DLYMVKDIAL
DLRHGLLFIL QSNKILRAGM DGEGLEVIVS SQGLDAFVAD PSSALLYYSQ GQEILAHNYF
KSGSTYRLAV IEGAESIISL AILEDQLFYA TRNSTKVVYT IQSFSLWRIL KETGEFAEKI
LSKPGQDEQQ RISAAKGYSA NLQPIPENHP CAINKGGCEG YCFGVLHDQV GGTRLKLKRF
IALMKRFWDG IGQCECVLTM ATLDSVGLRT TASIWSNKSV LLAGGLITIA IAIIVTLCIV
LPNFNDSNKV VENNEGIGDK ENSLILIIEN HGCLLTIWNV RDLNSTGTIL KHNSTSNVDC
YFDLFLNHSI YYNDNVKSIK STSPSYPNMI LPANFYSSLI EKPSHVPVVD FVNEKIYAIS
TRKSGEAPKL FVLDLWKPLY AILLADLDEP TDLALDPTMG LLFISQRSSI ARVSMDGSNM
TKILENPRLA SVLSIDRSVK RIYWSSQSNI ESVDYAGGNR QVITSITSLP LSLTVMRGQI
IWLTINITGR KMLWTCRLNK TTGLCDSVRE LQLNNNENMT KIKGYDSEEI SSIMNSTSNP
CATDNGGCEQ FCLLSNSVSK GYSCACKSGQ RLKEDKKSCV GSTDQDFLMY VQGAFARGKM
FNHLGANDSE ELRFGEAIYP VGLRLLPLDK YDTIYFAYDV RERLIYQVEK GSIVETSLIE
YDRQPALVDI IPKSEALYLT TDWVSKLIYV CTNMAKKSSA NEIRIYPYHY YANMEGYKIL
VQFEKKYRLG SIVAHPNRGY VFFIMAELGA TSIQTRLVRI NSDGTGKHFF LENERLQRFG
LAIDFLDDRL YWFSKDGTEL KSIKVDGSMD SLRSINISMI SYPMSMSFDK NFAYVGNWTH
VWCLDKATGA SAVHLKHVNP DMQDFLSGVS YHNLAAQPII DNHPCVIDKG GCQTFCFAVP
DEKTPKKLNK KCGCFEGENL QFDGKSFEMA LKKCFLWGGA LVVITVAISV TLYLVLPGSN
DGAKGTENSG NGGHGSNETN GESNNGAENG GNASNEENES GGENNIKAFP RTLVIKSGSC
ILTGMDVDNL SNRTFVHEDS SIGSDCQFDL YLRDSIFYND HPESIKSTSV KYPEMTIPVN
YYTSGFKQSW YTLAVDFVNK KVYAISTKIS GEAYKLFVLD MLKQHYAIVL TDLDAPTDLV
LDPAVGLLFI SQQSSILRTS MDGSSPTTIL NLPGLAPVVS LDRSTQRIYW ATQSAIESVD
YAGNGRRAVV KISTSPPTDL ASIGNRIFWL TAVSASSNKK TLWTCQTKGE SDACDSAEVV
QLADDYNIGQ IKAYDFQELY SVVRTKSNPC RKDNGGCEQL CLLSNSSSEG YSCACELGQK
LKEDQKSCTG TIGQGFLMYV QGLFFRSRMM DHLGIKDEES RFGEAIYPVN VFTGPLNKAK
VIHFAHDVRE HLAYYVDDKD VRELSLVEIS KKPFIIDSTS HSEIYIATDW VSKTIYFSMS
SFEDWRRENS LRVYPYGYFS NNRYYKSLAS YNDQYRIRSV VVHPNRGYVF YILTELNSDT
SRLVRINSDG SDKQDFLENR RVREIGLSID FLDDRLYWFS EDGTKLVNVK IDGSIDSLRS
IDISMVSAPQ TMTFDESFAY VSNWAGVWRL DKATGASAVR LKHVNPESRE MLSGVSYHSP
EAQPLIDNHP CAVNKGGCRR FCFAVPDSKE PVGLKKQCGC YDDETLQPDG RTSFAVIAIA
VIVLLWLFLP GLNNKPEGEG NQGSTSTENS QSTESNESTE GAQSTESNES TEGVRSTESN
ESTEGLQSTE SNESTEGVQS TESNESTEGV QSTESNESGE SNEGENVEAF SRMLVFETSS
CKLTALDVEN LTNSSIIHEG FNSSQTCNFE LYLKDSIFFI NSTDTIKSTS DSYPEMKMPA
NEFSIGFNVV SYAMEVDFTN KKLYAISKDY TEDYKLFVLD LVKQHYSIIL TDLFMPTDLA
LDPAVGLLFI LHYSSILRVS MDGLSPTNIV QQPANSPLDP VVSVDRTEQR VYWSTYTRVE
SADYDGNDKR FFALVSVFPT HLRVIGSHLF WSNDSSLWTC QTDEKTSLCS SAKQLKLKDD
EAIGEIKAYD FNEMYSIVNS KPNPCAKNNG GCEQLCLLSN STSEGYSCAC ELGQKLKEDQ
KSCVGATDQG FLMYLQDNFI RGRMLDRLGI NDNDEPRFGE VIYPVFTPSF TVEKAKVRHF
AHDVHERVVY FADDIAVWKV SLVEIKKQLL RVEDFDCKLR LATDWVSKMI YVSMSSYDDV
DTKINNELRV YLYDYYFNPI AVEYNRHYKS LLRYDDQYRL RSVVAHPNRG YVFYVLTEVK
SNNSRLVRIN SDGSDRQYFL DNRRVREIGL TIDFLEDRLC WFSEDGTKLE SVKIDGSIDS
LRSIDISMVS EPYSMTFDEN FAYVSNFTCA WRLNKKTGDS AVHLKHVNPE RNVNYPNLLA
GVSYHSKAAQ PILENHPCFV DNGGCEAFCF ALPDSKEPTR LKKQCGCLED ETLRPDGRSC
VKNV
//
