ID A0A232F0X3_9HYME Unreviewed; 523 AA.
AC A0A232F0X3;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=SH3 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TSAR_009621 {ECO:0000313|EMBL:OXU24436.1};
OS Trichomalopsis sarcophagae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Proctotrupomorpha;
OC Chalcidoidea; Pteromalidae; Pteromalinae; Trichomalopsis.
OX NCBI_TaxID=543379 {ECO:0000313|EMBL:OXU24436.1, ECO:0000313|Proteomes:UP000215335};
RN [1] {ECO:0000313|EMBL:OXU24436.1, ECO:0000313|Proteomes:UP000215335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Alberta {ECO:0000313|EMBL:OXU24436.1,
RC ECO:0000313|Proteomes:UP000215335};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXU24436.1};
RX PubMed=28648823; DOI=10.1016/j.cub.2017.05.032;
RA Martinson E.O., Mrinalini, Kelkar Y.D., Chang C.H., Werren J.H.;
RT "The Evolution of Venom by Co-option of Single-Copy Genes.";
RL Curr. Biol. 27:2007-2013(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the JIP scaffold family.
CC {ECO:0000256|ARBA:ARBA00009866}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXU24436.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NNAY01001299; OXU24436.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A232F0X3; -.
DR STRING; 543379.A0A232F0X3; -.
DR Proteomes; UP000215335; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR GO; GO:0046328; P:regulation of JNK cascade; IEA:InterPro.
DR CDD; cd01212; PTB_JIP; 1.
DR CDD; cd11801; SH3_JIP1_like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR047178; JIP1_scaffold.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR47437; JNK-INTERACTING PROTEIN 1-LIKE PROTEIN; 1.
DR PANTHER; PTHR47437:SF4; SH3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000215335};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 296..357
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 372..516
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 38..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..225
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..261
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 523 AA; 57606 MW; 89D69756078FE8E2 CRC64;
MADSEFEQFR YYFERLPQHL KAPISNYTLV HDVMLDDSPT SSQGSDAEVA SRSAGGVAGD
SEDEEVVVLH RHEAHSGHSS ADDSEDCEQM CCSSIVADSD FSGGKMRAGI NGGRDSVISD
IGDSCSSLNS WPTPEHHPRQ QAQIQPNGSN NGGTERRRRR LPEIPKNKKS LSCPLSMQSS
PSLAEELGAA AAAAAAAANR PHLIFRKCHP SLRHPEDDSP DSERMATDSG HSTAHSPDNG
PKSVSPIPCS SLRNIDSVSP DSTPAHWVKR IDFKIGTRAM RCVAGSGGVP FTQLELLEAT
HRGLHKFVPR HRDEIDLEIG DPIYVQKEAD DLWCEGVNLR TGRQGIFPSA YAVDMDYSDF
DPAAPKVKKE RYLLGYLGSV ETLAHKGTSV VCQAVRRIVG NSSQDSPVSQ SCILEVSDQG
LRMVDRSKPR VPCLYALALQ KNTGPCHDYF YSLKNVSFCA FHPRDHRYLG FITKHPTLQR
FACHVFIGQD STRPVAEAVG RAFHRFYTKF IETAFPIEDI YIE
//
