ID A0A232F7T6_9HYME Unreviewed; 517 AA.
AC A0A232F7T6;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Fascin domain-containing protein {ECO:0000259|Pfam:PF06268};
GN ORFNames=TSAR_010847 {ECO:0000313|EMBL:OXU26662.1};
OS Trichomalopsis sarcophagae.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Proctotrupomorpha;
OC Chalcidoidea; Pteromalidae; Pteromalinae; Trichomalopsis.
OX NCBI_TaxID=543379 {ECO:0000313|EMBL:OXU26662.1, ECO:0000313|Proteomes:UP000215335};
RN [1] {ECO:0000313|EMBL:OXU26662.1, ECO:0000313|Proteomes:UP000215335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Alberta {ECO:0000313|EMBL:OXU26662.1,
RC ECO:0000313|Proteomes:UP000215335};
RC TISSUE=Whole body {ECO:0000313|EMBL:OXU26662.1};
RX PubMed=28648823; DOI=10.1016/j.cub.2017.05.032;
RA Martinson E.O., Mrinalini, Kelkar Y.D., Chang C.H., Werren J.H.;
RT "The Evolution of Venom by Co-option of Single-Copy Genes.";
RL Curr. Biol. 27:2007-2013(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the fascin family.
CC {ECO:0000256|ARBA:ARBA00007415}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXU26662.1}.
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DR EMBL; NNAY01000754; OXU26662.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A232F7T6; -.
DR STRING; 543379.A0A232F7T6; -.
DR Proteomes; UP000215335; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:InterPro.
DR GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR CDD; cd00257; Fascin; 4.
DR Gene3D; 2.80.10.50; -; 4.
DR InterPro; IPR008999; Actin-crosslinking.
DR InterPro; IPR010431; Fascin.
DR InterPro; IPR022768; Fascin-domain.
DR InterPro; IPR024703; Fascin_metazoans.
DR PANTHER; PTHR10551; FASCIN; 1.
DR PANTHER; PTHR10551:SF9; PROTEIN SINGED; 1.
DR Pfam; PF06268; Fascin; 4.
DR PIRSF; PIRSF005682; Fascin; 1.
DR SUPFAM; SSF50405; Actin-crosslinking proteins; 4.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000215335}.
FT DOMAIN 28..137
FT /note="Fascin"
FT /evidence="ECO:0000259|Pfam:PF06268"
FT DOMAIN 147..271
FT /note="Fascin"
FT /evidence="ECO:0000259|Pfam:PF06268"
FT DOMAIN 285..389
FT /note="Fascin"
FT /evidence="ECO:0000259|Pfam:PF06268"
FT DOMAIN 426..516
FT /note="Fascin"
FT /evidence="ECO:0000259|Pfam:PF06268"
SQ SEQUENCE 517 AA; 57614 MW; C6F58C1ADE7E909E CRC64;
MQSNGTEHSE NGVDKTGWTI GLINGKFKYL TAETFGFKIN ANGASLKKKQ LWTLEGNEHQ
VYLRSHLDRY LAVDQFGNVT CEAEDPSDPG CAFQIQLACD GSGRWALKNV QRGYFLGSSQ
DELKCTAKAP GESEYWLVHL AARPQVNLRS AGRKRFAHLS ASQDEIHVDA PVPWGEDTLF
TLEFRGPSEH VDARGKPEGG HYALHTCNNK YLARDGKLLE TCTRDCLYAA EFHAGLLALR
DISGGYLAPI GSKAVLKSRS TTVTRDELFS LEDSLPQASF VAALNQRYVS VKQGVDVTAN
QDEISGHETF QLEFDRTTKR WYVRTMQDRY WSLESGGGIQ ASEHKRSSNG LFDLLWQPED
GTVALRANNG KYLATKRSGH LYANADNVNV ENDACKYYFY LMNRPVLVLR CEQGFVGPKS
AASPKLECNK AGYETIRVER CERGVVRFKG QNGKYWHADS EGVTVDSDVP ACGFYLELRE
PSRLCIKATD GRYLSAGKNG ALRLGETDYA SATKWEF
//
