ID A0A232LRT4_9EURO Unreviewed; 876 AA.
AC A0A232LRT4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Rad4 beta-hairpin domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=Egran_05495 {ECO:0000313|EMBL:OXV06738.1};
OS Elaphomyces granulatus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Elaphomycetaceae; Elaphomyces.
OX NCBI_TaxID=519963 {ECO:0000313|EMBL:OXV06738.1, ECO:0000313|Proteomes:UP000243515};
RN [1] {ECO:0000313|EMBL:OXV06738.1, ECO:0000313|Proteomes:UP000243515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OSC145934 {ECO:0000313|EMBL:OXV06738.1,
RC ECO:0000313|Proteomes:UP000243515};
RX PubMed=25753751; DOI=10.1111/1462-2920.12840;
RA Quandt C.A., Kohler A., Hesse C.N., Sharpton T.J., Martin F.,
RA Spatafora J.W.;
RT "Metagenome sequence of Elaphomyces granulatus from sporocarp tissue
RT reveals Ascomycota ectomycorrhizal fingerprints of genome expansion and a
RT Proteobacteria-rich microbiome.";
RL Environ. Microbiol. 17:2952-2968(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXV06738.1}.
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DR EMBL; NPHW01005460; OXV06738.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A232LRT4; -.
DR OrthoDB; 181129at2759; -.
DR Proteomes; UP000243515; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000243515}.
FT DOMAIN 515..574
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 576..639
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 646..720
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 811..876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..222
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 828..842
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..876
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 876 AA; 98472 MW; EB6A294F0D6890AB CRC64;
MPPFVSRKRS LSPAPPPPKR AARTPFYQKV IEICDSSDES SLSDLPSSEN EDSESKGIEE
GEKRNQEEDH DGDGDDSEDA VDWEDAVAAS KPTSHEPPGE DLELTLDKTA VHLSDLLDGR
KAPSRIEREI RINTHRLHVQ CLLFHNALRN AWINDPEIHT ILLRQLPAGI QKEIQLWRAA
SALEPLSQSP CKPSHDKKGR RQARSDRTWN DEAYRAEPDQ PDMSHGDPLI SLLRVLAAYW
KKSFCITAPG LRKRGYCPIS VLEEDTSTFQ RGEHDPVRHG ERIQSKEEFR TLAESRQGSR
DVGAQLFTAL LRALGIEARL VASLQPLGFG WANAEVYQTS PVIESSPVEN SDDEIGGSLT
KDENASYDHD LPFPIYWVEA ASPVTHRIIP VDPLVLSNSV ATTPDQVAAF EPRGSRAAKA
KQVIAYVVAY SADGTAKDVT TRYLRRRTWP GKTKGSRLPV EKITVSQSRA TTRYIEYDWF
RVTMRGYTRQ IDRRTKVDEI ENAQDLVPNQ PERKTATGEA DTLQNLRAST EFVLERFLRR
EEAIRPGAQH VRTFISGRGN KTREEKVFRR ADIVKCLSAE SWHKEGRQVR AGQVPLKRVP
IRVVTLLRKR AVDELERQTG AKPLQGLYAR HQTEVIIPPP IENGVIPKNE YGNIDCFVPS
MVPHGAVHLP WGGTARVCKK LGIDYAEAVT GFEFGSKMAV PVIEGVVIAE ENGDLVRDAW
RVDQEARHQR QRLQQEKRIL QTWRKFLMGL RITERVRAEY GEDGDVETMN PFAIRPSVRA
EPTATVDHGG GFLLPGDDDD NATLVVERPG TAAEIGESRA RGQEQQRNNY SVRHREEVES
TSGNAPERIG HFLSNENDDS SNDDDGEDDY EEVEDD
//
