ID A0A233RE58_9GAMM Unreviewed; 496 AA.
AC A0A233RE58;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN Name=mmsA {ECO:0000313|EMBL:OXY81674.1};
GN ORFNames=B6S08_11985 {ECO:0000313|EMBL:OXY81674.1};
OS Oceanimonas doudoroffii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Oceanimonas.
OX NCBI_TaxID=84158 {ECO:0000313|EMBL:OXY81674.1, ECO:0000313|Proteomes:UP000242757};
RN [1] {ECO:0000313|EMBL:OXY81674.1, ECO:0000313|Proteomes:UP000242757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27123 {ECO:0000313|EMBL:OXY81674.1,
RC ECO:0000313|Proteomes:UP000242757};
RA Brennan M.A., Maclea K.S., Mcclelland W.D., Trachtenberg A.M.;
RT "A Genome Sequence of Oceanimonas doudoroffii ATCC 27123T.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OXY81674.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NBIM01000003; OXY81674.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A233RE58; -.
DR OrthoDB; 9812625at2; -.
DR Proteomes; UP000242757; Unassembled WGS sequence.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:InterPro.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF4; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000242757}.
FT DOMAIN 19..477
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 496 AA; 53764 MW; 2CD5C1E868112A01 CRC64;
MNQLGHHING ETVTGRGDRH SAVFNPATGL QTAQLTLATG AEVEDAIQAA TRALPSWSAT
PAVRRARIMM KFLQLLNDNI DELALLISRE HGKVLDDARG EVTRGIEVVE FACGIPHLLK
GEYSENVGTR VDSWSVRQPV GVCAGISPFN FPVMVPLWMF PIAIACGNTF IMKPSEKDPT
STLRLAELFA EAGLPAGVFN VVNGDKEAVD TLLTHPGISA VSFVGSTPIA RYVQRVGIEH
GKRVQALGGA KNHAIIMPDA DLDSTVNALM GAAYGSAGER CMAISVAVAV GDIADPLMAA
LKERLEELRV LPGTHPDAEM GPLVTREHLD TVLSFVDSGL KEGAKLVVDG RRTDHPDHGD
GFFMGGCLFD HVTPDMRIYQ QEIFGPVLSV VRVDDYEQAL ELINRHEYGN GTAIFTREGH
AAREFAARVQ AGMVGINVPI PVPMAFHSFG GWKGSLFGDH HMHGMEGVRF FTKLKTITSR
WQENNTQSQF SMPTMK
//
