ID A0A235B4E3_9BACL Unreviewed; 105 AA.
AC A0A235B4E3;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=Anti-sigma factor antagonist {ECO:0000256|RuleBase:RU003749};
GN ORFNames=CHM34_14575 {ECO:0000313|EMBL:OYD06777.1};
OS Paludifilum halophilum.
OC Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC Paludifilum.
OX NCBI_TaxID=1642702 {ECO:0000313|EMBL:OYD06777.1, ECO:0000313|Proteomes:UP000215459};
RN [1] {ECO:0000313|EMBL:OYD06777.1, ECO:0000313|Proteomes:UP000215459}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 102817 {ECO:0000313|EMBL:OYD06777.1,
RC ECO:0000313|Proteomes:UP000215459};
RA Belbahri L.;
RT "The genome sequence of Paludifilum halophilum highlights mechanisms for
RT microbial adaptation to high salt environemnts.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Positive regulator of sigma-B activity. Non-phosphorylated
CC RsbV binds to RsbW, preventing its association with sigma-B. When
CC phosphorylated, releases RsbW, which is then free to complex with and
CC inactivate sigma-B. {ECO:0000256|ARBA:ARBA00024670}.
CC -!- SIMILARITY: Belongs to the anti-sigma-factor antagonist family.
CC {ECO:0000256|ARBA:ARBA00009013, ECO:0000256|RuleBase:RU003749}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYD06777.1}.
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DR EMBL; NOWF01000009; OYD06777.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A235B4E3; -.
DR OrthoDB; 9793697at2; -.
DR Proteomes; UP000215459; Unassembled WGS sequence.
DR GO; GO:0043856; F:anti-sigma factor antagonist activity; IEA:InterPro.
DR CDD; cd07043; STAS_anti-anti-sigma_factors; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR003658; Anti-sigma_ant.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00377; ant_ant_sig; 1.
DR PANTHER; PTHR33495; ANTI-SIGMA FACTOR ANTAGONIST TM_1081-RELATED-RELATED; 1.
DR PANTHER; PTHR33495:SF9; ANTI-SIGMA-B FACTOR ANTAGONIST; 1.
DR Pfam; PF01740; STAS; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000215459}.
FT DOMAIN 16..105
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 105 AA; 11512 MW; 1F836A670E3A5741 CRC64;
MNVSIEEKPG TGQSTMLVVS GEVDAYTAPQ LREKLMPLCE QNREVYLDLS RVDYMDSTGL
GVLIGAYKSL RSQKGRLVLV GVSPRLSRLL KITGLTEIIE IEDGA
//
