ID A0A235B9I0_9BACL Unreviewed; 560 AA.
AC A0A235B9I0;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=CHM34_03810 {ECO:0000313|EMBL:OYD08916.1};
OS Paludifilum halophilum.
OC Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC Paludifilum.
OX NCBI_TaxID=1642702 {ECO:0000313|EMBL:OYD08916.1, ECO:0000313|Proteomes:UP000215459};
RN [1] {ECO:0000313|EMBL:OYD08916.1, ECO:0000313|Proteomes:UP000215459}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 102817 {ECO:0000313|EMBL:OYD08916.1,
RC ECO:0000313|Proteomes:UP000215459};
RA Belbahri L.;
RT "The genome sequence of Paludifilum halophilum highlights mechanisms for
RT microbial adaptation to high salt environemnts.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYD08916.1}.
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DR EMBL; NOWF01000002; OYD08916.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A235B9I0; -.
DR OrthoDB; 9802848at2; -.
DR Proteomes; UP000215459; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:OYD08916.1};
KW Helicase {ECO:0000313|EMBL:OYD08916.1};
KW Hydrolase {ECO:0000313|EMBL:OYD08916.1};
KW Nucleotide-binding {ECO:0000313|EMBL:OYD08916.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000215459}.
FT DOMAIN 201..357
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 412..559
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 560 AA; 63824 MW; 521808B507B1A174 CRC64;
MESCWERPLI VQSDRTVLLE ANHRRFQEVR DRLSAFAELV KCPDHIHTYR ITSLSMWNAA
AAGMSGKEIV EVLTDNSKFP LPLSLEQEIE KTVSRYGQLR LKPRGQKVVL TSRDGELLSE
VARLPSVRRR AEPMADGSLL FARDQRGPIK QELIKYGYPV DDRAGYTQGE PLPLQLRNPS
RSGAEFVLRD YQKRAVEAFY RNGSPEGGNG VLVLPCGAGK TIVGLAALER VGRAALILAP
NTTSVRQWIR ELLDKTDLSE EQVGEYTGSL KEVKPVTVAT YQILTHRASQ EEPFTHMELF
HRRDWGLILY DEVHLLPAPV FRATADLQAR RRLGLTATLV REDGREEDVF SLIGPKIYDV
PWKELEEKGW IAGASCTEIR TPMAREHRHI YAEAGKRKKY RIAAENPDKL NVLESILQRH
EEDQVLVIGQ YLSQLKQIAE RLDAPLITGK TGQQQRERLY RRFRKGEISV LVVSKVANFA
VDLPDARVAV QISGTFGSRQ EEAQRLGRIL RPKKGENQSH FYHIVTRNTV DQDYALNRQL
FLVEQGYRYT IVDAEQWELI
//
