ID   A0A235F7Q5_9BACI        Unreviewed;       275 AA.
AC   A0A235F7Q5;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Pur operon repressor {ECO:0000256|ARBA:ARBA00018449};
GN   ORFNames=CGZ90_14565 {ECO:0000313|EMBL:OYD57007.1};
OS   Fictibacillus aquaticus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Fictibacillus.
OX   NCBI_TaxID=2021314 {ECO:0000313|EMBL:OYD57007.1, ECO:0000313|Proteomes:UP000215059};
RN   [1] {ECO:0000313|EMBL:OYD57007.1, ECO:0000313|Proteomes:UP000215059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GDSW-R2A3 {ECO:0000313|EMBL:OYD57007.1,
RC   ECO:0000313|Proteomes:UP000215059};
RA   Mayilraj S.;
RT   "Fictibacillus sp. nov. GDSW-R2A3 Genome sequencing and assembly.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC       family. {ECO:0000256|ARBA:ARBA00008391}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYD57007.1}.
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DR   EMBL; NOII01000007; OYD57007.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A235F7Q5; -.
DR   OrthoDB; 4213751at2; -.
DR   Proteomes; UP000215059; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0045982; P:negative regulation of purine nucleobase metabolic process; IEA:InterPro.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   InterPro; IPR015265; PuR_N.
DR   InterPro; IPR010078; PurR_Bsub.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR01743; purR_Bsub; 1.
DR   PANTHER; PTHR43864; HYPOXANTHINE/GUANINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR43864:SF2; PUR OPERON REPRESSOR; 1.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   Pfam; PF09182; PuR_N; 1.
DR   SUPFAM; SSF53271; PRTase-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215059};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT   DOMAIN          4..73
FT                   /note="Bacterial purine repressor N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09182"
FT   DOMAIN          111..245
FT                   /note="Phosphoribosyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00156"
SQ   SEQUENCE   275 AA;  30296 MW;  BF7E4E0DC8C2B332 CRC64;
     MKLKRSGRMV DLTTYLLQHP HQLIPLSYFV ERYESAKSSI SEDLAIIKEH FEQYGYGKIT
     TVPGAAGGVR YVPGISDKEA EQIINELVQQ LEDPSRILPG GYLYVTDIIG HPHLVNQIGR
     LFASSFASRK IDVVMTIATK GIPLAYAVAS HLNVPVVIVR SNSRVTEGST VSINYVSGST
     KRIQTMALAR RSIKQGSNVL IIDDFMKAGG TIKGMISIIS EFQANLAGIG VLVEAQEVSE
     RLVDDYVSLA RLSEVNEREN RIEVRPGNYF QGKGE
//