ID A0A235HR66_9NOSO Unreviewed; 808 AA.
AC A0A235HR66;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CDG77_24220 {ECO:0000313|EMBL:OYD88340.1};
OS Nostoc sp. 'Peltigera membranacea cyanobiont' 213.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=2014530 {ECO:0000313|EMBL:OYD88340.1, ECO:0000313|Proteomes:UP000215421};
RN [1] {ECO:0000313|EMBL:OYD88340.1, ECO:0000313|Proteomes:UP000215421}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=213 {ECO:0000313|EMBL:OYD88340.1,
RC ECO:0000313|Proteomes:UP000215421};
RA Gagunashvili A.N., Andresson O.S.;
RT "Distinctive characters of Nostoc genomes in cyanolichens.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYD88340.1}.
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DR EMBL; NOLI01000107; OYD88340.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A235HR66; -.
DR Proteomes; UP000215421; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:OYD88340.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000313|EMBL:OYD88340.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 347..573
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 598..714
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 647
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 808 AA; 90237 MW; 646AAFCCE61866A8 CRC64;
MIRANSSGSV ANRGNHPSRN LLIRFILGGT TLVVSISAYF SYQAARNMML KDLRQSAFLE
VKRGVAEIEE WLHVRQVEVQ TLANTSTVRS LNWPVAEPYL KGEVKRINEF FLFQIANPDA
SYSNTKVGRS NKNIRDRDYF KKAIAGKSNI SDPFISRSTG IPLIAISTPI WSNSANSSSP
IGAFQGNVRV DRITEVVNSL EYGTNSYAFA LNSQGQAIAH PNSALMSTLE KPAPSLLKMS
DRNLNAIAQR MVNKQQGIEL MEIDGTKKYV AYLPLQAANW SVALVIPRQN IESRLQFLDA
IALIVGGLTV TMITVLWQVQ AFEQRELKKS KTAADTANHA KSEFLANMSH ELRTPLNGIL
GCAQILLRSP ALPNQEQYHV NIIEQCGSHL LTLINDILDL SKIEAKKLEL HPYDVHLPSF
LQGIVEICHI RAKEKGILFV YKPAIDLPIG VHIDVKRLRQ VLLNLLGNAI KFTDEGQVTF
NIEVINRPPS DGQTLKHRLR FIVEDTGIGI TPAELSKIFL PFEQVGEKKR QAEGTGLGLA
ITRQLVEMMD SDIHVQSQIG QGSSFWFELE IPEAIDWVQS AIASSEKQII GFEGSAYTIL
MVDDRWENRT VITNLLQPLG FDVVEASNGK EGLEKAIALK PDLIITDLLM PEMDGFELIK
HLRQTPEIKD VFIIVSSASV FEADQNRSLQ AGGNAFLTKP IQLDELLHQL EQYLNLVWIY
RQSQPDGEKA KEAIIVTAQL TPPSPQVLQE IVTLATKGNF NAILKWADQL EETDITFTPF
ANELRQLARQ FDEDLILTFL TKYVVQTV
//
