ID A0A235HYN1_9NOSO Unreviewed; 310 AA.
AC A0A235HYN1;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=CDG76_31685 {ECO:0000313|EMBL:OYD90285.1};
OS Nostoc sp. 'Peltigera membranacea cyanobiont' 210A.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=2014529 {ECO:0000313|EMBL:OYD90285.1, ECO:0000313|Proteomes:UP000215440};
RN [1] {ECO:0000313|EMBL:OYD90285.1, ECO:0000313|Proteomes:UP000215440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=210A {ECO:0000313|EMBL:OYD90285.1,
RC ECO:0000313|Proteomes:UP000215440};
RA Gagunashvili A.N., Andresson O.S.;
RT "Distinctive characters of Nostoc genomes in cyanolichens.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYD90285.1}.
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DR EMBL; NOLJ01000013; OYD90285.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A235HYN1; -.
DR OrthoDB; 7510992at2; -.
DR Proteomes; UP000215440; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Hydrolase {ECO:0000313|EMBL:OYD90285.1}.
FT DOMAIN 102..284
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 310 AA; 34683 MW; E3B075F81E794604 CRC64;
MIFFNKDEQL ENLGNGILDA TWAAFPTLAR NQIALTWVVY DPPVRVNTGG ALTPNAFWDH
PVRGFTYRGV ERIYPASVVK LFYLVAVNEW LEKGMSQTSK ELERALRDMI VDSSNDATSL
VVDILSGTTS GPQLPTGPFE TWKYQRNIIN RYYQSLGWEE METINVCQKT WSDGPYGRER
AFVGELLENR NMLTTNAIAR LLHSIVGGVA VSSARSQTMM ALLKRPLNDL PTDRDEDQVT
GFLGGGLPKN AQIWSKAGWT SQVHHDAAYI ELPEQRPYLL VVFTEGKAQA KSRDILPFVS
KLVAEAISSL
//
