ID A0A235I480_9NOSO Unreviewed; 863 AA.
AC A0A235I480;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Chloride channel protein {ECO:0000313|EMBL:OYD92869.1};
GN ORFNames=CDG76_19295 {ECO:0000313|EMBL:OYD92869.1};
OS Nostoc sp. 'Peltigera membranacea cyanobiont' 210A.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=2014529 {ECO:0000313|EMBL:OYD92869.1, ECO:0000313|Proteomes:UP000215440};
RN [1] {ECO:0000313|EMBL:OYD92869.1, ECO:0000313|Proteomes:UP000215440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=210A {ECO:0000313|EMBL:OYD92869.1,
RC ECO:0000313|Proteomes:UP000215440};
RA Gagunashvili A.N., Andresson O.S.;
RT "Distinctive characters of Nostoc genomes in cyanolichens.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYD92869.1}.
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DR EMBL; NOLJ01000006; OYD92869.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A235I480; -.
DR OrthoDB; 9812438at2; -.
DR Proteomes; UP000215440; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd01031; EriC; 1.
DR CDD; cd01988; Na_H_Antiporter_C; 1.
DR CDD; cd00293; USP_Like; 1.
DR Gene3D; 3.40.50.12370; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45711; CHLORIDE CHANNEL PROTEIN; 1.
DR PANTHER; PTHR45711:SF10; CHLORIDE CHANNEL PROTEIN; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00582; Usp; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Chloride {ECO:0000256|ARBA:ARBA00023214};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 454..511
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 517..575
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 863 AA; 92386 MW; E103A4C3E9C0D5CF CRC64;
MLARGKILWL RLSRQLVQPR RLAFVEACLI GLVSGLAAVL LGQAVDWAGA LRVRVSYLLP
AYLVLPGIGL VGGLLAGWLV ERFAPEASGS GMSEVKAVLA RVPMPLNLRI ALVKLIGATL
VLGSGMPLGR EGPTVQIGAA LANQLSNWAP TSPEHRRQLI AAGAGAGLAA AFNAPIAGVL
FVVEELLQDV SGITLGTAIL ASFIASVISR LYGSHSLDLN HLNLGLPDTT FFAQEIPFYL
ILGVLAGLLG ILFNKGILGS LAINRRLVRL SLSWRIGIAG LVSGVAIAFL PAAFRDHAGL
REILLVGSAN WSFAAIALLV QFTLIIFTYG SGAPGGLLVP TLALGAALGY LVGAVEHSLL
GMSAATVYAH VGMAAFFSAV SKVPITAVVI VFEMTTDFNL VLPLMIASVV AYLVAEKIDH
RSLYDLLLEW KGIHITKEPT TEGLLAQLSA VDVMQRRVET LSSQMSTDEA VQAFSHSHHR
NFPVLENGKV VGIVTQKDLV NIASEQLGKD TTISEIMTPE PVTVTPTATL AHVLHILNRY
HLSCLPVTEG RKLIGIITRS DIIRVEAEQL SGNSEQIERK SAPSYVVYQT RAPATGKGRL
LVPLSHPQTA ETLLEMAVAI AKDRNYEIEC LQVIIVSSSR IPSETPVQIS KSLQLLQRAI
LLGENSRIPV HTQIRVAHNV AGAILETVKE RHIDLVLMGW KGTTSTPGRV FSRVVDTIIR
QAGCDVILAK LDDKRSFDRW LLPMAGGPNS SQAIKLLPAL ASLSTSPQIK LCQVFQPTNS
IPDTTLLDKS VRFLQRRVSG KVMATPVRAN SVSDAVLNCA KLDNSDVIVL GASRESLLQQ
AIQGNIAENI SRKSNCTVIM VKT
//
