ID A0A235IA03_9NOSO Unreviewed; 422 AA.
AC A0A235IA03;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:OYD94314.1};
GN ORFNames=CDG77_11775 {ECO:0000313|EMBL:OYD94314.1};
OS Nostoc sp. 'Peltigera membranacea cyanobiont' 213.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=2014530 {ECO:0000313|EMBL:OYD94314.1, ECO:0000313|Proteomes:UP000215421};
RN [1] {ECO:0000313|EMBL:OYD94314.1, ECO:0000313|Proteomes:UP000215421}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=213 {ECO:0000313|EMBL:OYD94314.1,
RC ECO:0000313|Proteomes:UP000215421};
RA Gagunashvili A.N., Andresson O.S.;
RT "Distinctive characters of Nostoc genomes in cyanolichens.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYD94314.1}.
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DR EMBL; NOLI01000032; OYD94314.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A235IA03; -.
DR Proteomes; UP000215421; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR24363; SERINE/THREONINE PROTEIN KINASE; 1.
DR PANTHER; PTHR24363:SF0; SERINE_THREONINE-PROTEIN KINASE DDB_G0277989-RELATED; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000313|EMBL:OYD94314.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:OYD94314.1};
KW Transferase {ECO:0000313|EMBL:OYD94314.1}.
FT DOMAIN 26..79
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 166..422
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 200
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 422 AA; 46798 MW; 39A49BCF6A473F03 CRC64;
MVSLTLLEPQ QKTPLQQWCF ENSSIIRIGR AADNHVVLTD SLVSRHHLEL RQVDSADNGG
GWRLISQGTN GTFLNGILVI QSPLPDNSLL QLAQGGPILQ FQIQEVTVLE TGLRSPQMQG
TEENAVATVY SAEGKYTCTH EGNSPNNLFC IHCGQPLSVQ QKIRHYQVLR TLGQGGMGTT
YLAWDGTGQI GSIPRLLVLK QMNADMVKIA KAQELFEREA HTLKSLNHPG IPKYYDFFVE
GGKKYLAMEL IQGQDLEKRV YTTGPVTPSL AIAWMIQTCD ILEYLHSQEP PLIHRDIKPA
NLMVRSSLNS IVVLDFGAVK EIGTAPGTRI GAEGYCAPEQ ERGQPLTQSD LYAIGPTLIF
LLTGENPFKY YRQRGRNFRF DVAKVPTISS QLRDVIDRAT EPLPRDRYQT AKELAAALAA
CQ
//
