ID A0A235IBZ7_9NOSO Unreviewed; 8206 AA.
AC A0A235IBZ7;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Non-ribosomal peptide synthetase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CDG77_11300 {ECO:0000313|EMBL:OYD95004.1};
OS Nostoc sp. 'Peltigera membranacea cyanobiont' 213.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=2014530 {ECO:0000313|EMBL:OYD95004.1, ECO:0000313|Proteomes:UP000215421};
RN [1] {ECO:0000313|EMBL:OYD95004.1, ECO:0000313|Proteomes:UP000215421}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=213 {ECO:0000313|EMBL:OYD95004.1,
RC ECO:0000313|Proteomes:UP000215421};
RA Gagunashvili A.N., Andresson O.S.;
RT "Distinctive characters of Nostoc genomes in cyanolichens.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYD95004.1}.
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DR EMBL; NOLI01000030; OYD95004.1; -; Genomic_DNA.
DR Proteomes; UP000215421; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0009403; P:toxin biosynthetic process; IEA:UniProt.
DR CDD; cd12116; A_NRPS_Ta1_like; 1.
DR CDD; cd17651; A_NRPS_VisG_like; 1.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd08953; KR_2_SDR_x; 2.
DR CDD; cd00833; PKS; 5.
DR Gene3D; 1.10.1240.100; -; 5.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.47.10; -; 5.
DR Gene3D; 3.40.50.980; -; 4.
DR Gene3D; 1.10.1200.10; ACP-like; 7.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 2.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF16197; KAsynt_C_assoc; 5.
DR Pfam; PF00109; ketoacyl-synt; 5.
DR Pfam; PF02801; Ketoacyl-synt_C; 5.
DR Pfam; PF08659; KR; 2.
DR Pfam; PF08242; Methyltransf_12; 2.
DR Pfam; PF21089; PKS_DH_N; 1.
DR Pfam; PF00550; PP-binding; 7.
DR Pfam; PF14765; PS-DH; 2.
DR SMART; SM00826; PKS_DH; 1.
DR SMART; SM00822; PKS_KR; 2.
DR SMART; SM00825; PKS_KS; 5.
DR SMART; SM00823; PKS_PP; 7.
DR SMART; SM01294; PKS_PP_betabranch; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 7.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 4.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
DR SUPFAM; SSF53901; Thiolase-like; 5.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 5.
DR PROSITE; PS00606; KS3_1; 2.
DR PROSITE; PS52004; KS3_2; 5.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 3.
PE 4: Predicted;
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 37..465
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 655..729
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1717..1792
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1829..2253
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 3629..3706
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3767..4196
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 4782..5203
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 6385..6804
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 7008..7082
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 8093..8168
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 3715..3759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6231..6252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6984..7006
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3717..3759
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 8206 AA; 910645 MW; 925DCA46253C1A5A CRC64;
MNTEEQLKCI EEAFYRDSMQ SLPSRQPELI VPPSFQIEPI AIVGVSGYLP GCMSVREFWQ
ALDADRSLIQ EIPGERFDSR KYYDPAGKDP GKTRCKWGGF IPDVAGFDAH FFKILPFDAK
QIDPRQRLLL MSVYQTLCDA GYAPATLKKS RTGVYVAHQD DDYLQILNER GLDPGEGYGQ
ASLLANRIAY FFDFRGPSEI VDAQCAGAAV ALHRAVSALR SGEISHAIVS AANLLLRPQP
FLALSRTKQL SRTNTVKSFQ ENADGHLRAE GVVSVMLKRL TQAEADGDFI YALISNTAVN
FNGQGGTSSA SPNIESHVDL IERCYGEAGI DPRDVSYIEA QGMGNRLSDL AEWEAFNRAL
RSLAKARGVT LDLHSCRIST LKPLIGHMES TSALGALLKI VRSLETEQIH KILGFSGADM
ALDTDNQPCV LASETLPWNK TDKPRLAGLH SFGMSGNNAH ILIQEYRPSE KEYSPTQSLP
VIQEFLIVLS AKSEKSLKAL ARELNQFLAT SLVPDLKDIA HTLYNGREHM DYRMAMVVRD
RQQLRAGLQS YIEAPDGIST KKGNPNVFIG TVSSAQEQDP SSFAGMQAIA AAWVQGSAIS
WPEHPTARRV PLPSYHFETQ RYWLDEGIQH PPSLAAIPKT GFQDFAIDPG QSSEENLRRY
LTCILVEFLD LPSDRIDENK HLQDYGIDSL AGMRVIRSLS ETFDIEVLGR DLLQHPTIRS
LSKHLSQRID LEANRPSNPQ VSEPENRELE FPLSEGQKGL WALQKSFPLM TAYNIPLCLK
IRNTIDASIL SKALKSLLRQ HPVLGYHLSE KDGILRQGLA PGTEIGINTE DVSVLDEQSI
LSKLREKSKQ PFNLEQGPLI RVDLLQKSST QTYLLICVHH IVFDGGSFLP LVDSLFDAYR
RLLHGESPLA APISTTYQDF VLWERQMLNG AWEKHRSYWR ETLSGNLPVL ELPTDRSRSK
AQLFSGAVIS TSIESSLAAQ IQSFSKAQRV NPSTIFLALF KILLHRYTNL DDIIVGMPSM
GRPQERFRSV VGYFINMVAI RSKGFSQQTF ATFLENLKYT MSDGLDHASV PFTTVVRDIG
ILPNAIAAPV FQVAFEYQNG LAPSDLQHLC SCYGDLFDLE ISFDIHQEGE YELVLEVFEE
ANGYRVSFKY NPSLYDATTI QQMLGHYLQL TQVAISNPNA LVHKYEMMDD AERRLIQWDL
NATSVEYPSN CVHQLFQEQV ERTPNAVAVA CGERTLSYEE LNRKSTALAK YLQQQGVQSE
TLVAVCVERS LDTIVALLGI MKAGGAYVPL DPQFPQERLT YMLRDCGATF LVTQSWLNNR
IGFIDAQYIN LDRQWEEIEQ DAESVEPLKC LAGLGNLAYV IYTSGSTGKP KGVTIEHRAL
TNFLCGMADQ IGKQFVADFL AVTTYSFDIA ALELFFPLIQ GGRCTICDRA RLKDVEAIKA
EIRRAKPTIM QATPSFWTML LQSGWKNDEN LKILCGGEML NDSLRSMFAS IGCEVWNLYG
PTETTIWSML AKIQPGDSVT IGKPIANTRV YILDAHDQLA PMGVPGELCI AGAGLARGYW
NQPELTAQKF IDHPLEANNG SKLYRTGDLC CWLPNGTLQH LGRLDLQVKI RGFRIELEEV
ERELSRHPAV AECVVVAKER QGVQSLIGYY VPRQSDEKNL LQDFDLIAHL KQRLPDYAIP
TAFVSLDRIP LTANGKVDRK SLADREVAIQ RKTEKVTAKT ETEAILADIW KNVLNVTDIS
INDGFFAAGG DSVLSVILAD RIARRFNQEF PVTSLFKYST IRDIAAYLGD KQAEILEETP
LQNLMSASHE DEQERSALAF DNAKGEALQD SLAIVGISCH FPDAPNHDQF WQNICAGKES
GQFFSEEELR QAGVSEDSIR NPHFVGVQRT IEGKGNFDPE FFNISPRNAV FMDPQFRLLL
MHAWRAVEDA GYVSSEIPRT SVFISASNSG YNTLVDKAGI IEATDEYTAW MLNQSGTIPT
TISYQLGFIG PSVFVHTNCS SSLAALSAAY QSLSLGQSDY ALVGASTLLP KSEIGYLHRP
GLNLSRDGHC RTFDAAADGL VAGEGVAVLL VKKAPLAIAD GDRIYALIRG IGINNDGRDK
AGFFAPSVRG QSQAIDMALN STGIGAETIG YIEAHGTGTK LGDPIEIQAL CDSYQKHTNQ
RQYCAIGSVK PNIGHLDTGA GLAGCIKVAM SLYHKKIPPS INFSQPNPAI DFERSPFFVI
DRLHEWEAAP WPRRAALSAF GIGGTNTHAI LEEYLPSPRL SPKKLNSPVL IVLSARKDER
LKEYVGSLAD YLEQGIAKPN DSSETEWLIN LAYTLQCGRQ PMESRVAFIA SSVEELLAKL
RRFATDWQPF EGCYFGSPSR ENQILKLFAG DEDIQGLLAQ WLVKKNVAKL AQVWIQGVKV
DWSRLYCDRL PSRISAPTYP FAPEYYWPTP NSSSVSFSTL APSHAIDPLQ HKNVSVSAQH
YSYEFTGHEF FLADHQIRHN GSGRKVLPAV VYLEMVHRAF WQSISHSLPN LEYPGNNDKA
VIVLSNVAWV QALFVDESPA VVELKLFDGA LNQMRFEIDS TFKGKTSLHC HGDAAVRFNT
VPILNLLELQ QQIRERQLSS AECYEIFRTL GVDYGPAHHA IDTLFLSAGK ASDRQVLAKL
VIPDAVAQEQ SRYILHPSLL DAGLQSCVGL LLTNSQESLR LALPSSLEQI EVYDSCAALM
WAWVRFAPET KKDSPIQRID IDLCTDDGKV AVRMKGFVAR EIRQQDSDAA VIQHQPKPLI
SNEIPPGLGS VTLKPVWDRV AIAPQADRSK DSLTVVFGAN QTWKDQIAEL HRTTVLVDSA
KPQSVEEFSK QIELLGLIDR LLWLAPAPIK YALDDDRLVD EQESGVLQLF RLLKSLFESG
YGKKSLALTV VTSQSVAVRP FETANPIAAS IHGLVATLKS EYPHWRVRLL DIDRGELPSL
AELFSDNDTA DFPLLARRDK QWFARKLIPI AFESNDFPAY KQKGVYVAIG GAGGVGEVWS
RHIIENYQAQ VIWIGRRELD DKIREKQAKL AAFGSKPLYI QADAKNKASL EKALEEIRQS
YSCINGVVHT AIELQDQSLA QMSITRFRTG LFAKAETSVR LVQVFQHEPL DFVLFFSSLI
SFGESPGQAN YAAGCSFLDA YAEQLGKDWA VSVKVMNWGY WGNTGVVADA TYRERMRQNG
IGSIESQQAM AALNRLLQGQ IDQLAFINLL KPQALEFVIE DEVLSVVGSA PSQTAHPVVE
NVAPEIRYSQ QWQLIRTHRT DARDALLQNL LLANLSEMGV LNSPNGRSLP MTYYHKWLDE
SIRLLQQNGL LIRQENVSSV EELWTMWQKA RRDWEGSASV TAEINLVEKC LHSLPDILSG
RKLPQDVIFP ESSLRLVEPL YRGNPVADFF NEVIGDAVVD AINSWDKGNG PIRILEVGAG
TGGTTVGLLQ KLAPYSDRIG EYCYTDISQA FLIHAQEHYA IDYPFLKVDR FNVEQPLSIQ
SIQPGSYDIV VATNVLHATK NIRQTVRNVK AAMRAGGQVF INEIGGNSLF SHLTFGLLEG
WWRFEDAEMR IPGCPALNSH TWKQVLQEEG FDAVKFPVQF AHDLGHQIVV ASSNGVIRQP
LLDKPHVEPE SVAQTQPDDS SNVQTNSIVS LQERTTEFVR QTLSEATRTP ANKVRLDTPF
EQYGVDSIVQ VGLIQKLEQV TGSLPNTILF EYSTTRELVD YLLAHHQEFL TASFPTRIDE
TEPTSSNSVS QSTNEDSPSP RVSPQPAQNT TASDTANAAS NASRFVQDDI AIVGIAGRYP
GAKNLDELWE VLRTGRSCIV EADRFRRSNL SDRKHSETPA RSHFGGFLND VYCFDRQLFG
VSEERAIAMP PEVRLFLEIT WETFEAAGYS RAALKQFQLR EKKGIGVFVG SMYSQYAWTN
PSRKEAVLSS NGTEWQIANQ VSHFFDLTGP SLVLNTACSS SLTAIHLACE SLRQGSCSMA
LAGGVNLTLE PSKFLSLERS NFLGSGQHSR SLGDGDGMIP SEGVGTLLLK PLSLAIADND
RIEGIIKSSF VNHSGGRQAF TAPDPAQQTQ LVLDSIARSG CDIETITYVE SAANGSSLGD
PIEIIALKNA FAKLTNKTGF CAIGSVKSNL GHLEAASGIS QIAKVLLQFQ QKTLVPTINA
TPRNPRIKLD NSPFYLQEQL SPWVPQSDSH NSDLPRRSLI NSFGAGGSYA NLIVEEYQDK
PSNTTSRPHP SETLLVFAAA TQKGLQSYLT RLQTYLREHP AISVADLASA LQLRDCNLEY
RLAAIASSTN QALNVVEQLA GHNVDVSNPG IYASFGGADL PTPKDAQLQS AIGDRDLFRL
ARYWAAGADI DFARLNRVDR KSCVVLPGYA FEHDKEFSYI IHDSQDDTQA TAEPLGSQTS
GGMTATYFYD EPFLQDHTLL GDRVLLGVTH ASLAMTDFFQ RFPHQRALCL KRLTFVQPII
VDRGEAVTVE IHTSEIPTGL NFEARYRCTT SKQLTQTAAT GHLQPDLYKE EYLDVERLLE
SSTPIGNLES IYQTVPAIRL GSSFRTIERL FRTSDGIIAT VCLTEQSRQE SHTYALHPLA
IDSAFLAAAP LLADAIGNDS NYLPFGIKEI YCVKVDNWRS LDRCWVYTRL VKNSGELILF
DADIISDNSL VVARLRGCSL KLLHDRKEPE QASLKSDSID ASILETSLAA DVLRYLIDKI
NITAQISIAE TEVNTNLMQL GLGSAELVAI AASIEQDTDL ELNATLFFEY PSLMEVTNFF
VDSHPAAFLQ LLGERKTQHR TIPEKLDSSI LQNHEKVSAN LHGDIAVIGM HSTYAECEDL
DRFWQLIRDG RDVIREVPRD RWDYRPWFDP NPGSEDKTYC KWGSFIKDAD KFDAAFFNIS
PREAMWMDPQ NRLLMQSMYA AAEDAGVVNQ LRGSNTGVFA GICFDDYAEK IVELGLPLDI
YTGTGRSGIS ANRISFWFDF KGPSMVINTA CSSSLVALHY ACQALRNQEC EMAFVGGANL
LLSSLHYRYF SKLGALSPTG HCHTFDAAAD GYVPAECIAS VLLKPLEQAE KDGDRIHAVI
KGTAFTHGGY TPSLSAPSVA GEENAIVKAW EDAGIDPETL TYIEAHGTGT KLGDPIETNS
LKNAFARYTN KTGFCAIGSV KANIGHAEGA AGITGLIKVI LQIKHRQIPP LANLKQLNPY
LKLEGSPLYI NRELTDWESE GVRRAGVSSF GFSGAFAHAV IEEYRSYTDS ECEFSGPFPI
VLSAKNNECL KGQVANLIAF LEENCSKNLQ YEENFLANLS YTLQVGREAM QTRLGFVVES
MAELRNKLQM AWKDSDTKSE LFYGESKSGK EYLASLLANR DVSEVIAGWM NNCEYAALVD
GWTKGMTVDW SKLYANEKPQ RISLPTYAFA RESYWICPLD GDEGQSDLKT EAKLYALVPC
WDAIPLLKAN LPFSDRTQRT LIIGVDAELK DDLRACFPNA SYFGNMAKNR IESLKGRLET
DSSWQHIIIV VPEDNCSLLD DGTVLSAQEG GILSVFRIAK SLLSAGYATK NLALTFMTTQ
IAAINKDESS NPVHSAVHGF AGVLAKELPS WNVRVLDLQK GRSLSSVDLE HFPDDSAGKV
FAWRDGEWYR QTPIPMRNVP TPQADEFHSA YKNRGVYVVI GGAGGIGSAW SRFVIENYDA
RVIWIGRRQI DDEIRQKIDT LKQIGHAPEY LQADASDRES LTEAYKSIKS RYSQIHGVIH
SAVGQFDQSL SEMDENRFRS ILSSKIDVSV NMATVFKHEP LDFMLFFSSI ISLTRGGGMS
GYAAGCAFKD SFAIELNRCL PFPVKVINWG YWNVGTGNTI PDATKIRMKQ CGIEPIASQQ
GLEALSGFLV SPLHQLALLK TTGLDRLDLV KDDEWLDVYP PVNPSCIESA LRQIPWHDHR
VAAIAKQYLE PIAAIETLLL RLLHGTLTSL DLLHPHATLS PALPEFYQLW LQESRRLAIA
LVPDSVQGNL SDIWDEWNRQ KIHWDSMPHI QAIVTLVDVC MRELPAILKA QKRATDIIFP
NGSMSLVEGI YERNAIATHF NELLAQTVVN YLQERCRVDE LTPIRILEIG AGTGSTTATL
LHHLEPLGNL VGEYLYTDIS PAFLVRAERH FAPKYPFLRT QLFDVDQPLS KQGIPIGSFD
IVIATNCIHA TANIRRSLRN AKAALRGQGV IFLNEITQIS LISHLTFGLL AGWWLAEDAR
VPGSPFLLAE DWKRVLQQEG FQAIAYPARS ADSLGQQVIV AVSDGVVRQP ESISSVPSPK
QQALNFRQPN DKEGASSALK ELKEKGTTYF KQLIGEVLMM DGNRIDPSEP LAVYGVDSII
IAQLTNALNK HFEGVKAGLL FEASTIDALV NHFAETQRTN FAKLVKLEDH PEPKAAIQES
TANKQPSTDF AAKTIALHQS RDPIADAIAV IGMSGRFPQA KTLTEFWENL QSGRDCITDL
PNNRWNMDGF FEADPKMARE QGKSYCKWGA FLEDFDTFDP LFFNISPREA AQMDPQARVF
LQECWRAFED AGYSPSGLDD AVRDRIGVYG AVTKVGFNTS FAAMVNRVSH AMDLRGASVA
VDTMCSSALV ALHQGCEALR RGDLQMAIVG AVNLYLDPRN YKYLCEVGLL AESKMPRVFG
EGGTGFVPGE GVGAVVLKRL EDARRDNDSI VAVIRSSAVN HSGRANAYGT PNPLRQAEVI
SQALDRGGID PRSVGYIESA AMGLEIADSL ELNALKKVFG DRAEDRWQCY RLGSLKSTIG
HGESVSAMAQ FMKVVLQLKH RKLCPTKVVR PLNPDIDFAS LPFQLQTELE PWSPLTIDGI
CLPRRAGITA LGSGGVNAHL IVEEYRREPS QETLKLAQDS PQIIILSAKN DDCRQAQISQ
LIEFLDRNQD VSLADLAFTL QVGREAMASR VALVVNSIDE LRSGLTHLML HTQSNLSRKI
STYVGNITET DNSLQTLLAG GADAMVLQLF LEQRNYEKLA QFWVQGGKIP WVSLWEQKQV
QRISLPNYPF EKRCFWEAAS SANSDEPKFN GAIAPDNSNP NDRPAASQSV QEIVTAIVAK
SIDLTESEIR PHLSLWQLGV DSIRSMEIAR RLQKRLHVEI GHRELADYGT VEALCRLIEQ
KRAAIALNVT SEIESVSEPQ TTSKVRVSTF PLSEGQRGLW LLHQLVPKMS AYNVPVTLQF
DRLVNVNAIK QAASFLMERH PILRSQFHTD DKGNPIQTIR SQTEFFFEDS DRDFATDAVL
QDRLRAAADR VFDLESDPLV RLHLFHQSQN HHKLLIVIHH LVVDGSSLPI LLHDFLHAYA
AFSKGSEPAI ASPESADYAD FVAWEQALIC SERGKASLSY WQKQLSGTLP LLALPFDREH
PPSQTYAGTT ISSKLESNTT HQLRALAKNQ NVSLFVLLLG IYQALLARYT LQSDIIVGVA
SAGRPEDRFA NTVGYFINMV PIRTQINVNE PFAELLQRLK ITVADGLDRG HFPFPKQVSE
LCISRDLAHS PVFQTSFAMQ SFWRPEVEQT LQNQLEGVSV VAGPSPAGEI ELRLEIVEQC
NEILVNMAYN TDLFEQPTIV RLAEHFSNLV KAVCQNPNQP IHSLQLLSKD EQRKLLNECS
IGDRVPKKAD NLQKCVHHLF EIQAQKTPEA VAVIHDQRSL TYLELDRQSA GLANRLREIG
VLPGMIVGIF TERSISQVVA ILAVLKAGAA YLPLDPAYPQ QRLTFVIEDA EPIVILTEEK
LRDRLINLFG SEKQRLPILS VEQGEVPQEI SPSPLLPANS LVYVIYTSGS TGQPKGVAMG
HGAVMNLIQW QISQAGEYQT PRTLQFASLN FDVSFQEIFS TLGGGGSLVL IDENVRTNPA
GLAKLIEDRQ IQRLYLPYVA LSSLAEQLRI SGRSLHTLRE VIIAGEALRI TSAISQMFRD
APRCILQNQY GPSETHVITS FTLEQDVNSW PVLPPIGCPI PGVAIYILDE HYNLMPIGIA
GEIFIGGECL AQGYLNNPEL TERKFVTNPF VSPLEGSVRE RIYATGDLGR YLPDGNIEYL
GRRDNQVKIR GFRIEPGEIE AVLETHPEVL STVVIAEADN PNFKRLIAYI VPQVHPPSTS
ELRSFLKQKL PDYMVPSAFV FLKALPVNPN GKVDRRALPK PEPTLLDEAN YVMPKTEVEK
IIAEVWQKAL QVEKVGICDN FFELGGHSLL LVQINQQLQA VLSSELSILD MFKYPTIQTL
SQYLSGNLLK QDTSDKNNSR SQIQSDIKAL KNGQLQLRRQ HRSRNQ
//
