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Database: UniProt
Entry: A0A235IHD5_9NOSO
LinkDB: A0A235IHD5_9NOSO
Original site: A0A235IHD5_9NOSO 
ID   A0A235IHD5_9NOSO        Unreviewed;       352 AA.
AC   A0A235IHD5;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   08-MAY-2019, entry version 8.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=CDG76_00325 {ECO:0000313|EMBL:OYD97383.1};
OS   Nostoc sp. 'Peltigera membranacea cyanobiont' 210A.
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=2014529 {ECO:0000313|EMBL:OYD97383.1, ECO:0000313|Proteomes:UP000215440};
RN   [1] {ECO:0000313|EMBL:OYD97383.1, ECO:0000313|Proteomes:UP000215440}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=210A {ECO:0000313|EMBL:OYD97383.1,
RC   ECO:0000313|Proteomes:UP000215440};
RA   Gagunashvili A.N., Andresson O.S.;
RT   "Distinctive characters of Nostoc genomes in cyanolichens.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OYD97383.1}.
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DR   EMBL; NOLJ01000001; OYD97383.1; -; Genomic_DNA.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000215440; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000215440};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       49    343       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   352 AA;  39258 MW;  7007292204B12044 CRC64;
     MHNKLFNSNI DNANIENDRI LLTPNEVKSK LPLTQLAEQR VLAYRQEIED ILDFKDRRKF
     IVVGPCSIHD PKAALEYSER LKILSERVKD NLLLVMRVYF EKPRTTVGWK GLINDPDMDD
     SFHVEKGLLI ARELLLKITE LGLPAGTEAL DPIIPQYISE LITWSAIGAR TTESQTHREM
     ASGLSMPVGF KNGTDGNIQV ALNALQSAGN PHNFLGINQN GQVSVFQTKG NGYGHVILRG
     GSQPNFDPAN VKLVEEKLKQ ANLPPRIVID CSHGNTNKDY KLQGAVLENI IQQIVDGNTS
     IVGMMLESHL YEGSQPITGK QEELKYGVSV TDKCISWEET EKIILAAHEK LK
//
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