ID A0A238BUS9_9BILA Unreviewed; 607 AA.
AC A0A238BUS9;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=ShTK domain protein {ECO:0000313|EMBL:OZC08450.1};
GN ORFNames=X798_04510 {ECO:0000313|EMBL:OZC08450.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|EMBL:OZC08450.1, ECO:0000313|Proteomes:UP000242913};
RN [1] {ECO:0000313|EMBL:OZC08450.1, ECO:0000313|Proteomes:UP000242913}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Red Deer {ECO:0000313|EMBL:OZC08450.1};
RA Mitreva M.;
RT "Draft genome of the nematode, Onchocerca flexuosa.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01005}.
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DR EMBL; KZ270008; OZC08450.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238BUS9; -.
DR Proteomes; UP000242913; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.10.1940; -; 1.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR003582; ShKT_dom.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF84; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF01549; ShK; 2.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SMART; SM00254; ShKT; 2.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS51670; SHKT; 2.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU01005};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000242913};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..607
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012104790"
FT DOMAIN 499..533
FT /note="ShKT"
FT /evidence="ECO:0000259|PROSITE:PS51670"
FT DOMAIN 543..578
FT /note="ShKT"
FT /evidence="ECO:0000259|PROSITE:PS51670"
FT DISULFID 499..533
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01005"
SQ SEQUENCE 607 AA; 69196 MW; 9CB7B0E1507055D1 CRC64;
MWFLLLLIPL MFAVEFISGQ AQISQEPNRF IRNCDQAPTP AIRSICLNLQ RMANNSRRNF
EEESRARIQP PGIPEHLRPG MVVPGSRGQV ASNPYDCMTL TCLCPYFRGE IDPRNQCVLG
NGQVIAMAYR KEYRTLTEVE RLRYHSALNV LKRSGEYDRL GRQHQSNCTH ILSNSMSKVA
GSGGAHSGPG FLPWHREFIK RFEIALRLID PSVSVPYWDS ILDSYLPDPR DSIFFSTIFM
GETDSFGNVI TGPFAYWDTL DGRSAIVRSL GREGQLFTEW NIQQVMQQNA IQNILAYTAP
MPGCPYPVNF GALEYSHSNV HLWVGGHMKP PEQSTSDPIF YSHHAFVDFI WELWRQDVQP
AWIRETAYAP DIPACADPQH FSYSLMRPFF TLYNRDGLSN MYTNQMYRFA SRPRCTAERP
TCGSPYLFCD TRGFPHCVSK IKLNGLCIGF EGFDACFNGT CQMGRCRPGP TPASFVPQTQ
LSQMQRAQIL QRQVRFVDCF NRHPCCETWA GIGECHRNGN FMRQYCQAAC HICSPSFNAN
SECVDRHISC RQWRINNQCR GNSDLFMEEN CRQSCGFCGT PKNASCPISV LIIIALYFSP
EKEKEKV
//
